Led a team through pooled screening based discovery campaigns to identify novel engineering modalities (i.e. switch receptors, endodomains, CRISPR) in NK and T cells to overcome therapeutic limitations in oncology and autoimmune disease spaces.

*Managed a direct report*Optimized transient delivery conditions for, and later executed, CRISPRa/i pooled screens in primary T cells

*Led a cross-functional team through a discovery campaign to ID synthetic signaling domains that improved CAR-T persistence in solid tumor settings*Designed functional assays to vet safety profile and performance of designs in primary T-cells*Binder discovery lead, responsible for the management of four separate binder discovery campaigns through collaborations with external and internal partners*COVID ambassador that contributed to building framework for lab-centric RTW policies, managed COVID-prevention compliance for 1/2 of Seattle site

*Developed a pooled screening method for the identification of promising VHH binding domains for CARs isolated from alpaca-derived PBMCs*Responsible for executing the entire CAR discovery pipeline from the selection of promising scFv sequences derived from in-house BCR sequencing pipeline -> functional assessments in immortalized T-cell line*Improved throughput by automating of existing methods methods on Lynx (Dynamic Devices) and Biomek (Beckman)

As a part of a group, helped build a high throughput screening platform to evaluate the therapeutic efficacy of antibody sequences derived from deep sequencing repertoires of tumor infiltrating lymphocytes (TILS), in a larger effort to discovery novel target antigens on solid tumor.Responsible for initial assay development of components of screening pipeline through tailoring established assays to fit our needs

Worked closely with Dr Steven Biller to determine why Prochlorococcus, the most abundant photosynthetic organism in the world, produces vesicles despite high energy expenditure and limited access to nutrients.Assisted large scale metagenomic project geared towards evaluating cyanobacterial diversity through developing a pipeline to process hundreds of filtered samples for sequencing; and in building a database both tracking sample progress in the pipeline/connecting sequences to how each sample was collected

Developed and maintained a database to house incoming patient survey data regarding recovery from ACL reconstructive surgery Took charge of scanning and correcting patient surveys based on operative reports and other patient intake informationOverhauled the system of the organization of patient information by electronically sorting data based on patient recovery

Focused on developing strategies to reduce glycerin glut associated with increased biodiesel productionAttempted to create new products from glycerin to increase its value by use of biological and chemical catalystsTrained and mentored a new undergraduate student to take my place upon graduation

Led a team of undergraduate students in the design of multiple T-cell therapies to target different subsets of B-cell lymphoma while overcoming the toxic tumor microenvironmentDeveloped mouse model to adequately test therapies: validated constructs will be moved to clinical trialsBecame proficient at completing several immunoengineering and microbiological techniques including ELISA, flow cytometry, Western Blotting, PCR, etcManaged and assigned projects to undergraduate studentsTaught mentees common laboratory techniques and basic microbiologyTrained newly hired post-doctoral associates in immunoengineering laboratory techniques