Maggie Tang Email & Phone Number

Utrecht, Utrecht, Netherlands

Rotterdam Area, Netherlands

A job which allows me to gain more experience in an environmental analytic laboratory. I am working with the LIMS system Nautilus to report the results of GC-FID analyses. Having problem-solving and organizing skills is a must-have to report the results within a given time. The measured samples includes Mineral Oil and Volatiles in water samples and ground extraction. Secondly, I am also responsible for the maintenance of the GC-FID apparatuses and keeping the troubleshooting guide updated so colleagues can solve errors easily within minutes. I am also the point of contact towards apparatus suppliers when bigger errors occur.Lastly, I have finished a yellow belt training (Lean Six Sigma) and have been in multiple continuous improvement projects. The outcome of these projects are mostly targeted to improve occuring practical problems, which are easily negated by small changes in working procedures.Tasks: preparing the standard solutions needed for the analysis of Mineral Oil; preparing the GC-FID; calculating, evaluating and reporting the obtained results in the LIMS system; troubleshooting of the analysis and the GC-FID system with backflush. Techniques/apparatuses: GC-FID, GC-MS, LTM, Backflush, LIMS (Nautilus).

Mijdrecht

Temporary job which mainly is about quality control on bulk raw materials and “special concretes”, fillers and plasters designated for the building industry. I have also been working on R&D for new products and also updated safety sheets of several products.

Rotterdam Area, Netherlands

A full-year job which allowed me to gain more experience in an environmental analytic laboratory. I have been working with the LIMS system Nautilus to report the results of GC-MS analyses. Having problem-solving and organizing skills was a must-have to report the results within a given time. The measured samples includes volatiles in water samples and ground extraction. Tasks: preparing the standard solutions for the calibration curve; preparing the head-space GC-MS; calculating, evaluating and reporting the obtained results in the LIMS system; trouble-shooting. Techniques/apparatuses: GC-MS (headspace), LIMS (Nautilus).

Amsterdam Area, Netherlands

Part-time job which requires me to show initiative with the customers, remain calm and professional in any kind of situation and taking orders of customers and execute these as well as I can.Tasks: preparing drinks and ice cream, bringing the orders to the customers, answering customer questions, receiving orders (by phone) and process them.

Rotterdam Area, Netherlands

Temporary job which allowed me to gain experience in an environmental analytic laboratory. I have been working with the LIMS system Nautilus to report the results of GC-MS analyses. Having problem-solving and organizing skills was a must-have to report the results within a given time. The measured samples includes water samples and ground extraction. Tasks: preparing the standard solutions for the calibration curve; preparing the head-space GC-MS; calculating, evaluating and reporting the obtained results in the LIMS system; trouble-shooting. Techniques/apparatuses: GC-MS(headspace), LIMS (Nautilus).

Amsterdam Area, Netherlands

Joining the kinase project provided by a PhD student at the Vrije Universiteit Amsterdam. I have been synthesising building blocks for the project and supervising interns. Optimizing synthesis steps by literature searching was also part of my job.Reactions: introduction of boronic acid pinacol-ester, aromatic substitution reaction, amide coupling, Suzuki couplings and ring closure (hydrazine).Techniques/apparatuses: TLC, manual/automated column, microwave, IR, 1H-NMR, 12C-NMR, HPLC-MS, melting point determination.

Nijmegen Area, Netherlands

Obtaining experience in a TI Pharma project by synthesising ligands for parasitic phosphodiesterases, which is found to be an excellent way to fight the African Sleeping Sickness. An explored synthesis route for the building block was used and refined to introduce variations on one site of the ligand. Amines, triazoles and tetrazoles were the interested moieties to be added to the scaffold.Other activities during this period were attending the weekly group meetings and monthly company meetings, working in teams on the lab, learning about the different aspects of medicinal chemistry and keeping the (electronic) labjournal up-to-date. One final presentation was given to conclude both Master’s internship periods.Reactions: Friedel-Crafts acylation, Ring closure (hydrazine), Alkylation reaction, Suzuki couplings, amide synthesis, click-chemistry with azide, Mitsunobu reaction, deprotection of TMS-group.Techniques/apparatuses: TLC, manual/automated reversed-phase column, automated normal-phase column, microwave, 1H-NMR, 12C-NMR, HPLC-MS.http://www.tipharma.com/pharmaceutical-research-results/research-details/result/jointly-fighting-neglected-diseases.html (06-11-2013)

Amsterdam Area, Netherlands

Obtaining experience in a TI Pharma project by synthesising ligands for parasitic phosphodiesterases, which is found to be an excellent way to fight the African Sleeping Sickness. A new synthesis route was scouted and optimized to obtain the interesting ligands.Other activities during this period were attending the weekly group meetings to discuss and learn from the other projects in the department, working in teams on the lab, learning about the different aspects of medicinal chemistry, supervising other interns and keeping the (electronic) labjournal up-to-date. Two presentations were given about this subproject I have been working on during the internship period.Reactions: esterification, ester hydrolysis, introduce a benzyl- and a ketal-clamp as protecting group.Techniques/apparatuses: TLC, Dean-Stark trap, Grignard reaction, manual/automated column, microwave, 1H-NMR, 12C-NMR, HPLC-MS, melting point determination.http://www.tipharma.com/pharmaceutical-research-results/research-details/result/jointly-fighting-neglected-diseases.html (06-11-2013)

De Meern

Analyzing starting materials, samples from the factory, final products and waste water according to the ISO norms by its physical and elemental properties. The samples were worked up according to the methods and analysed via different apparatuses and techniques. If different values were found than the expected values after a second and a third analysis performed by me and a co-worker, direct feedback was then given to the factory for immediate adjustments.Techniques/apparatuses: volumetric flasks, volume pipettes, high-temperature stoves, AAS, ICP, pore-volume determination (mercury), CHNS/O Elemental Analyzer, particle-size determination, manual and automatic titration.Note: I worked full-time during school vacations and part-time on weekends and summer 2009.

Amsterdam Area, Netherlands

Continuing with my project at the VU after HBO graduation, provided by my ex-supervisor. I synthesized more ligands and building blocks for the project and working side-by-side with my lab-partners.Reactions: protection/deprotection of a primary amine, converting a sulphonate to a sulfonylchloride, aromatic substitution, Suzuki couplings, ringclosure and deprotection of a Boc-protecting group.Techniques/apparatuses: TLC, manual/automated column, microwave, 1H-NMR, 12C-NMR, HPLC-MS, melting point determination.Note: I worked full-time during the summer holiday and part-time during the first period of my Master's.

Amsterdam Area, Netherlands

Obtaining experience in organic chemistry by synthesising ligands for a histamine receptor. During my internship I synthesized building blocks and performed parallel synthesis of the variation on the amines. After combining the two synthesis routes and performing two more reaction steps, the product of interest was synthesized. Two presentations were given about the project I have been working on during the internship period.Other activities during this period were attending the weekly group meetings to discuss and learn from the other projects in the department, working in teams on the lab, learning about the different aspects of medicinal chemistry, keeping the written labjournal up-to-date.This experience led to my love for the pharmacology branch of chemistry, which caught my full attention ever since.Reactions: protection/deprotection of a primary amine, converting a sulphonate to a sulfonylchloride, aromatic substitution, Suzuki couplings, ringclosure and deprotection of a Boc-protecting group.Techniques/apparatuses: TLC, manual/automated column, microwave, 1H-NMR, 12C-NMR, HPLC-MS, melting point determination.

Maarssen

Obtained knowledge about working with several ISO norms to conduct several analyses. Applied chemistry was used in the laboratory, which includes performing accurate and reproducible manual titrations, determining the flash point of new products and starting materials, and also working with pH indicators.My research project was concerning about the effect of new cleaning agents on polymers in a set period. The polymers used in several furniture and apparatuses might weaken on a longer time period due to the basic properties of these cleaning agents. Therefore a risk assessment, according to ISO norms, were conducted to determine the effect of these cleaning agents on commonly used polymers polymethylmetacrylate and polycarbonate.Other activities during this period were attending the introduction week by touring through the factory, fire emergency training (fire extinguishers) and writing reports about the research to find the source behind the returned products from international clients.

Master Of Science (Msc), Drug Discovery And Safety

Activities and Societies: VCSVU.Mandatory courses: - Physical-Organic Chemistry - Principles of Pharmaceutical Sciences/Pharmacochemistry.

Hbo, Chemie (Organische Chemie)

Activities and Societies: None.Verplichte vakken (Mandatory courses): - Biomoleculaire Chemie (Biomolecular Chemistry) - Gedrag en.

Havo, Natuur En Techniek + Natuur En Gezondheid

Activities and Societies: None.Verplichte vakken (Mandatory subjects): - Nederlands (Dutch) - Duits (German) - Engels (English) - Algemene.