Mahbbat Ali Email and Phone Number
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-Motivated R&D group leader scientist in a biopharma industry with great experience of upstream and downstream process development that includes, but not limited to mammalian and bacterial cell culture, large-scale protein expression and purification using UPLC, HPLC, along with several other chromatographic techniques.-Highly experienced in bio-physical characterization of different enzymes using several bio-physical techniques such as time-resolved UV-Vis spectropotentiometry, EPR, Mass spectrometry, and biochemical characterization using different spectrophotometric, fluorometric and chemiluminescent assays such as Transcreener, ADP glow, Nano glow.-Experienced in characterizing small molecules, proteins, protein fragments and peptides using different analytical instrumentation such as HPLC, GC, and mass spectroscopy.-Highly skilled and experienced in method development and validation along with biochemical, cellular assays development and validation.-Handful experienced in protocol, MoA, and tech manual writing and reviewing.-Extensively knowledgeable and experienced in data processing and analysis of experimental results obtained from the aforementioned instruments. -Proven ability to work as an independent researcher in a dynamic setting and at the same time able to work smoothly in a collaborative environment. Excellent communication skill with proven strong leadership potential.-Always eager to improve and highly capable of adapting into new working environments and open to accept new challenges.
Bellbrook Labs
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Senior ScientistBellbrook Labs Jan 2022 - PresentMadison, Wisconsin, Us1. Enzymatic assay development using Transcreener® assay platform• Developed and validated several enzymatic assay systems using Transcreener® assay platform.• Performed purification of CMP polyclonal antibodies from serum bleed and ran assays to determine the selectivity, sensitivity, and specificity of that purified antibody. • Performed immunoglobulin titration against different flours to prepare tracers for the Transcreener® assay.• Performed ELISA and other assays to determine the dose response inhibition, toxicity, viability, selectivity and specificity of drug molecules.• Train several scientists and associate scientists. 2. Drug development for autoimmune disease• Performed many biochemical and cell based (THP1, PBMC) assays for internal drug development program to discover drug for the autoimmune disease.• Grown and maintained the THP1 and PBMC cell to perform assay including dose response inhibition, specificity, selectivity, toxicity, and viability.
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Postdoctoral Research AssociateIndiana University Bloomington Jan 2021 - Dec 2021Bloomington, Indiana, Us•Performed the incorporation unnatural amino acid into different sites of FynSH3 protein by amber codon suppression and characterization of the ligand bound FynSH3 protein by mass spectra.•Accomplished the purification and characterization of human membrane protein and membrane scaffold protein (MSP) using Bio-Rad chromatography system -
Postdoctoral Research AssociateThe Johns Hopkins University Jan 2020 - Dec 2020Baltimore, Md, Us•Performed the docking the substrate into the active site of the enzyme Polyoxin Dihydroxylase (Po1L) and screened the better active variant of Po1L by harnessing the directed evolution•Accomplished site saturation and point mutation of azurin to get more variants of azurin. Constructed a new vector and clone the mutating azurin into new vector. -
Research And Teaching AssistantUniversity Of Wisconsin-Milwaukee Jan 2014 - Jan 2020Milwaukee, Wi, Us•Designed and executed extensive spectro-potentiometric experiments to characterize cytochrome c nitrite reductase (ccNiR), and trapped and characterized the putative intermediates of ccNiR-catalyzed nitrite reduction.•Performed steady-state kinetics analysis of ccNiR-catalyzed nitrite reduction by weak reducing agents.•Improved the protocol for culturing Shewanella oneidensis on a 50 L scale, and for purifying ccNiR from these large-scale cultures using AKTA chromatography system
Mahbbat Ali Skills
Mahbbat Ali Education Details
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University Of Wisconsin-MilwaukeeBiochemistry And Structural Biology -
University Of DhakaAnalytical/Physical Chemistry
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University Of DhakaChemistry
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Shailakupa Govt Degree CollegeScience
Frequently Asked Questions about Mahbbat Ali
What company does Mahbbat Ali work for?
Mahbbat Ali works for Bellbrook Labs
What is Mahbbat Ali's role at the current company?
Mahbbat Ali's current role is Senior scientist at BellBrook Lab l Drug Discovery and Development I Enzymatic Assay Development l Bio-analytical chemistry I Chemical Biology I Enzymology.
What is Mahbbat Ali's email address?
Mahbbat Ali's email address is ma****@****iub.edu
What schools did Mahbbat Ali attend?
Mahbbat Ali attended University Of Wisconsin-Milwaukee, University Of Dhaka, University Of Dhaka, Shailakupa Govt Degree College.
What are some of Mahbbat Ali's interests?
Mahbbat Ali has interest in Social Services, Development Work, Economic Empowerment, Civil Rights And Social Action, Politics, Traveling, Education, Environment, Poverty Alleviation, Science And Technology.
What skills is Mahbbat Ali known for?
Mahbbat Ali has skills like Research, Teaching, Data Analysis, Microsoft Office, Powerpoint, Leadership, Public Speaking, English, Quantum Chemistry, Reaction Kinetics, Management, Project Management.
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