Manale Karam (Doldur) is a PhD, Oncology at IterOnco.
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Founder And Chief Executive OfficerIteronco Jul 2024 - PresentParis-Saclay -
Senior Scientific Officer / Research And Development ManagerAc Bioscience Sa 2019 - 2023Lausanne, Vaud, SwitzerlandResearch topic:- Modulation of the tumor microenvironment (vasculature and immune systems) to improve cancer treatment. -
ResearcherQatar Biomedical Research Institute - Qbri 2013 - 2019Doha, QatarResearch topics:- Cancer immunotherapy: Mechanisms and targeting strategies for breast cancer immune escape from NK cell cytotoxicity.- Generation and differentiation of human pluripotent stem cells (hESCs, hiPSCs) in diabetes research. -
Visiting LecturerHamad Bin Khalifa University 2015 - 2018Doha, QatarTaught the following topics in the graduate program at the College of Science and Engineering:- Role of NK lymphocytes in cancer immunosurveillance and immunotherapy- Signaling pathways in Cancer- Cancer stem cells- Hematopoietic stem cells- Mesenchymal stem cells- Toll-like receptors: signaling pathways- Capping and poly-adenylation mechanisms and their impact on mRNA fate- Techniques in biochemistry and molecular and cellular biology -
Visiting LecturerQatar University 2014 - 2017Doha, QatarTaught the following topics in the graduate program at the Department of Biomedical Sciences, College of Health Sciences:- Overview of the hallmarks of cancer biology and cancer signaling- Multistep tumorigenesis and evolution of cancer- Cancer metastasis- Cancer chemotherapy- Targeted cancer therapies- Endocrine disorders and functions- Molecular subtype-directed therapy in breast cancer: from chemotherapy and targeted therapy to immunotherapy- Regulation of the cell cycle and RB protein -
Postdoctoral ResearcherÉcole Normale Supérieure Paris-Saclay 2012 - 2013Cachan, Île-De-France, FranceResearch topics:- Protein kinase C isoforms in the regulation of the epithelial-mesenchymal transition in metastatic melanoma.- Pharmacological screening of protein kinase D1 (PKD1) inhibitors with antitumoral therapeutic potential. -
Visiting LecturerÉcole Normale Supérieure Paris-Saclay 2012 - 2013Cachan, Île-De-France, FranceTaught the following topic in the graduate program at the Department of Biology:- Role of the cytoskeleton in cancer: Cell adhesion and cancer -
Visiting LecturerUniversité Paris-Saclay 2012 - 2013Villejuif, Île-De-France, FranceTaught the following topics in the graduate program at the Faculty of Medicine:- The anti-tumoral pharmacology tools: Molecular and cellular models- Mechanisms of resistance and sensitivity to anti-cancer agents: genetic and biochemical analysis -
Doctoral ResearcherÉcole Normale Supérieure Paris-Saclay 2008 - 2011Cachan, Île-De-France, FranceResearch topics:- Role of PKD1 in ER-positive breast cancer cell dependence to estrogens and resistance to antiestrogen treatments.- Analysis of crosstalks between receptor tyrosine kinases (RTKs) to identify new regulatory mechanisms of the insulin-like growth factor (IGF) signaling pathway. -
Research Msc InternÉcole Normale Supérieure Paris-Saclay 2007 - 2008Cachan, Île-De-France, FranceResearch topic:- Role of protein kinase D1 in breast tumorigenesis.
Manale Karam (Doldur) Education Details
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Phd. Cellular And Molecular Biology (Doctoral School Of Oncology) -
Clinical Research Graduate Program -
Cancer Biology And Therapeutics Graduate Program -
Msc. Oncology - Pharmacology And Therapeutics -
Bsc. Biochemistry -
Collège Des Sœurs Des Saints-Cœurs SioufiBaccalaureate, Scientific Section
Frequently Asked Questions about Manale Karam (Doldur)
What company does Manale Karam (Doldur) work for?
Manale Karam (Doldur) works for Iteronco
What is Manale Karam (Doldur)'s role at the current company?
Manale Karam (Doldur)'s current role is PhD, Oncology.
What schools did Manale Karam (Doldur) attend?
Manale Karam (Doldur) attended Université Paris-Saclay, Boston University School Of Medicine, Harvard Medical School, École Normale Supérieure Paris-Saclay, Holy Spirit University Of Kaslik - Usek, Collège Des Sœurs Des Saints-Cœurs Sioufi.
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