Maneesh Kumar, Ph.D. Email & Phone Number

San Diego, California, Us

San Diego, California, Us

Lawrence Township, Nj, Us

Lawrence Township, Nj, Us

Lawrence Township, Nj, Us

As a Scientist, I implement robust research methodologies for IND enabling studies aligned with standard policies and procedures while ensuring timely and cost-effective accomplishment of overall projects. My utmost priority is to achieve research goals with mutual consensus and for this, I build a strong collaboration with internal and external groups.Key Achievements:- Spearheaded CRISPR-Cas9-mediated gene editing in primary immune cell types, such as monocytes, macrophages, dendritic cells, myeloid-derived suppressor cells, t-cells, and cancer cell lines through the implementation of multiple protocols.- Employed analytical techniques for gene editing readouts for verification/validation of potential drug targets in cancer and immune cells in the context of tumor micro-environment.- Developed and transferred assays for gene edited drug products in cell therapy space

Albany, N.Y., Us

In my role, I designed, executed pertinent experiments, analyzed the data, as well as prepared comprehensive reports for recording research findings and facilitating informed decision making. I also contributed to grant proposal submissions securing continuous financing for research projects.Key Achievements:- Led four cancer-centered research projects from conception to successful completion, ultimately resulting in grants, publications, and off-shoot projects.- Played a key role in diiscovering oncogenic and cancer driving RNA biomarkers acting pan-cancer.- Developed a novel method for targeted therapeutics in breast and lung cancers by re-purposing existing FDA-approved drugs conjugating with RNA aptamers.- Improved skill set of junior scientists through effective training and guidance that enabled scientists to work independently.

In

Protein-protein interaction, Cancer Biology, Telomerase biology, Cancer Metastasis, protein phosphorylationAchievements: * Discovered novel molecular mechanism behind regulation of telomerase in cancer* Helped establish non-canonical roles of the gene NME2 in genomic regulation* Established many novel tools and techniques in the lab Responsibilities:* Leading the team, designing experiments, executing, troubleshooting and documentation/presentation for the project* Advise graduate students, provide insight into other projects running in the lab * Helping in managing the lab, occasionally conducting staff meetings on behalf of lab head* Coordinating between lab group and the medical coordinators for availing patient tumor samples

Delhi, Delhi, In

Achievements: * Pioneered the research demonstrating non-cholinergic functions of the erstwhile neuro-transmitter gene acetylcholinesterase in insect system * Developed a novel method to reduce the application of harmful chemical pesticides in crop plants by harnessing RNAi mechanism induced in insects but generated by host plants* Secured many fellowships for self and also research grants for the lab with P.I.Responsibilities: * Leading the RNAi group in the lab * Designing, executing, troubleshooting and documentation/presentation for the project, * Advise five junior graduate students and many undergraduate students * Helping in other projects running in the lab, reviewing manuscripts * Helping in managing the lab, occasionally conducting staff meetings on behalf of lab head, * Coordinating between different collaborating groups * Person-in-charge for many equipment for departmental Central Instrumentation Facility * Seminar coordinator for the department

Doctor Of Philosophy - Phd, Molecular Biology

Master'S Degree, Genetics