Marc Prindle Email and Phone Number
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I am a molecular and cellular biologist with a strong interest in cancer biology and DNA sequencing technologies. I am also very interested in the way we study disease, and the potential of nucleic acid sequencing in the clinic and the field.
Roche Diagnostics Seattle
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Roche Diagnostics SeattleSeattle, Wa, Us
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Director Of Protein EngineeringRoche Diagnostics Seattle May 2020 - PresentI lead the Protein Engineering team to continually improve the performance and quality of our polymerase, the key enzyme that makes Sequencing by Expansion work. The Seattle team is heavily focused on realizing the initial goal of Stratos Genomics: producing a robust chemistry for generating rapid, inexpensive sequencing that is the world standard for clinical diagnostics.
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ScientistStratos Genomics Sep 2014 - PresentSeattle, Wa, UsAs a member of the Protein Engineering group, I worked to advance our polymerase designs and purification methods in support of our Sequencing by Expansion technology.
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Director Of Protein EngineeringStratos Genomics Mar 2016 - May 2020Seattle, Wa, UsI lead a growing team performing R&D in support of Stratos Genomics' goal of creating a robust, reliable, and affordable platform for massively parallel nanopore DNA sequencing. My primary responsibilities are managing the work and direction of the group, communicating progress to our CEO, communicating changing company priorities back to the group, and coordinating efforts between Protein Engineering and the other development groups at Stratos Genomics.
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Senior ScientistStratos Genomics Jan 2015 - May 2020Seattle, Wa, UsI led a small team in efforts to improve our protein purification methods and to design new polymerase mutants, both in-house and in collaboration with our strategic partners.
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Research ScientistUniversity Of Washington Dec 2013 - Sep 2014Development of Duplex DNA Sequencing technology for applications such as subclonal detection of cancer-predisposing mutations, and highly accurate sequencing of formalin-fixed archival samples.
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Post-Doctoral FellowUniversity Of Washington Nov 2008 - Dec 2013As a graduate student, I characterized the function of a novel DNA damage signaling protein, ultimately placing it in the 53BP1/SMC1 axis. As a postdoctoral fellow in the Loeb laboratory, I have explored the contributions of replicative DNA polymerases to mutagenesis, contributed to the development and evaluation of a platform for directed molecular evolution, and initiated an ongoing project to identify compounds to kill cancer cells by modulating the mutation rate. Over the past year, I have been developing Duplex Sequencing, a highly accurate next-gen sequencing technology that was conceived in the Loeb lab, for use on the following projects: 1) Probing DNA derived from primary tumors for rare subclones that could be sentinels of relapse; 2)Obtaining reliable sequence from FFPE archival samples; 3)Assessing very short-term mutation accrual as a consequence of environmental exposure.
Marc Prindle Skills
Marc Prindle Education Details
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University Of MichiganCell/Cellular And Molecular Biology -
University Of North Carolina At CharlotteBiology
Frequently Asked Questions about Marc Prindle
What company does Marc Prindle work for?
Marc Prindle works for Roche Diagnostics Seattle
What is Marc Prindle's role at the current company?
Marc Prindle's current role is Director of Protein Engineering at Roche Diagnostics Seattle.
What is Marc Prindle's email address?
Marc Prindle's email address is mp****@****ics.com
What is Marc Prindle's direct phone number?
Marc Prindle's direct phone number is +120644*****
What schools did Marc Prindle attend?
Marc Prindle attended University Of Michigan, University Of North Carolina At Charlotte.
What are some of Marc Prindle's interests?
Marc Prindle has interest in Cooking, I Enjoy Spending Time With My Family, Traveling, Politics, Environment, Poverty Alleviation, Science And Technology, Camping, Board Games.
What skills is Marc Prindle known for?
Marc Prindle has skills like Cell, Molecular Biology, Genomics, Biochemistry, Dna, Protein Chemistry, Mutagenesis, Protein Purification, Cancer, Dna Sequencing, Sequencing, Molecular Cloning.
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