Marcel Thalen

Marcel Thalen Email and Phone Number

CEO at BioLyo Technologies @
Marcel Thalen's Location
Ghent, Flemish Region, Belgium, Belgium
Marcel Thalen's Contact Details

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About Marcel Thalen

I am currently employed as CEO BioLyo Technologies, a spin out of Iliad Biotechnologies. BioLyo is a CDMO solely focussed on live biologicals, i.e. live vaccines and microbiome derived products. At this point we offer medium development, fermentation and lyophilization development, process characterization. The GMP facility will be operational early 2024. Before Iliad, I worked at GT Biologics (now 4D Pharma) and Qu Biologics in similar roles, being responsible for process development and GMP manufacture of the lead products, both indications being Crohn's disease. Before Qu Biologics, I worked as Scientic Officer for SynCo Bio Partners (now Wacker), a leading Contract Manufacturing Organisation, as part of Business Development. I was involved in all incoming projects at SynCo from a scientific and a business perspective, designing cost-effective production processes whether for live or for protein biologicals. I've also acted as a consultant for SynCo's clients, helping the client with their in-house development prior to transfer of the production process to SynCo. Prior to working for SynCo l worked at the Netherlands Vaccine Institute for 14 years in various positions, the last position being the head of the Process Development Department. At the NVI I was involved in the optimization of the production processes of diphtheria, tetanus, pertussis, inactivated polio, meningitis vaccine, getting a PhD on pertussis, the causative agent of Whooping Cough "Whooping cough vaccines: production of virulent biomass"(ISBN number: 978-90-8504-953-1).Specialties: Fermentation and processing of pathogens, lactic acid bacteria, anaerobes, i.e. bugs with an impaired metabolism, preferably using disposable technology. Also, developing production processes for live organisms as the active ingredient, including lyo-development. My current Drug Development work at Iliad Biotechnologies focuses on the production of intact, live and active B. pertussis cells.

Marcel Thalen's Current Company Details
BioLyo Technologies

Biolyo Technologies

CEO at BioLyo Technologies
Marcel Thalen Work Experience Details
  • Biolyo Technologies
    Ceo
    Biolyo Technologies Apr 2020 - Present
    BioLyo Technologies: live bacterial products done right!
  • Iliad Biotechnologies
    General Manager International Operations
    Iliad Biotechnologies Jul 2014 - Nov 2021
    Iliad is a clinical stage biotech company, focussed on the eradication of whooping cough by developing a truly improved pertussis vaccine. As General Manager I am responsible for the Company’s International Operations, including process development, GMP manufacturing, and overseeing collaborative research at partner institutions. My role is to: • Create strategy and planning for process development to create stable and manufacturable vaccines• Direct Contract Manufacturing Organizations (CMO’s)• Supervise European R&D activities at partner research institutions• Company Liaison to European clinical research sites• Assist the VP of Development in reporting to the Scientific Advisory Board (SAB), Joint Steering Committee, and Investors on a regular basis• Work with regulatory affairs consultants to create the CMC portion of regulatory filings
  • Gt Biologics
    Director Drug Development
    Gt Biologics Nov 2013 - Jun 2014
    After consulting part time for GT Biologics for 4 months, I joined the company full time in November 2013. GT Biologics is a preclinical stage biotech company with a platform technology, that identifies human gut bacteria that have strong immunomodulatory activity with a defined mode of action. The presence or absence of these bacteria have been shown to be important in Crohn's disease as well as a number of autoimmune disorders. As part of the management team my main current role was to identify & select and project manage all CMOs delivering services to GT Biologics such as cell banking, process development and GMP manufacture (fermentation, lyophilization and encapsulation). Other responsibilities included writing the CMC sections for the CTA of GT's lead product Thetanix, meant to treat juvenile Crohn's disease.
  • Qu Biologics Inc
    Vice President Drug Development
    Qu Biologics Inc May 2012 - Sep 2013
    Burnaby, British Columbia, Ca
    After consulting part time for Qu Biologics for a year, I joined the company full time in May 2012, immigrating from the Netherlands to Vancouver, Canada. Qu Biologics is a clinical stage biotech company with a platform technology, Site Specific Immunomodulators (SSIs), that stimulate the body’s innate immune system to mount a response against various forms of cancer (Lung, Colon, Skin), as well as a number of autoimmune disorders (Crohn’s Disease, Ulcerative Colitis, Arthritis). The unique aspect of Qu Biologics is that a significant amount of data has been gathered in human subject by means of ‘named patient use’ programs in Austria and the Bahamas, i.e. there is a significant amount of data showing the potential of SSI’s to transform the way cancer and auto-immune diseases are treated.As Vice-President Drug Development, reporting to the CEO, I fulfilled a number of different roles:- Oversight and project management of all aspects of manufacturing and testing related to Qu’s drug products for use in clinical trials, including writing CMC sections.- Identification, establishment and management of relationships with CMOs for both non-GMP and GMP manufacturing- Set-up and manage an in-house fermentation laboratory, including purchasing equipment, supervising a qualified fermentation scientist and co-op students- Overseeing all aspects of research and development (R&D) around existing technologies, as well as R&D around optimizing immunological response and new administration technologies to be developed and tested in house.- In addition I contribute to the preclinical research, helping to identify and optimize suitable animal models that will correlate with the effects SSIs have in humans.
  • Synco Bio Partners
    Scientific Officer & Business Development Manager
    Synco Bio Partners Nov 2008 - Apr 2012
    Involved in all incoming projects from a scientific and business strategy perspectiveActively pursuiing and managing new and existing customers
  • Synco Bio Partners
    Scientific Officer & Project Manager
    Synco Bio Partners May 2004 - Oct 2008
    Involved in all incoming projects from a scientific perspectiveProject and accountmanagement for a number of clients
  • Netherlands Vaccine Institute
    Project Manager/Head Process Development
    Netherlands Vaccine Institute Oct 1999 - Apr 2004
    Nl
    head of process developmentproject manager removal of animal substances from production processes for diphtheria, tetanus and polioproject leader pertussis optimization & scale-up
  • Rivm
    Bio Process Engineer
    Rivm 1990 - 1999
    Bilthoven, Utrecht, Nl

Marcel Thalen Skills

Biotechnology Life Sciences Vaccines Fermentation Microbiology Research Cell Culture Biochemistry Science R&d Lifesciences Gmp Immunology Clinical Development Drug Development Biopharmaceuticals Genomics Protein Chemistry Technology Transfer Process Simulation Cancer Chromatography Molecular Biology

Marcel Thalen Education Details

  • Wageningen University & Research
    Wageningen University & Research
    Molecular Sciences & Biotechnology
  • Wageningen University & Research
    Wageningen University & Research
    Biotechnology

Frequently Asked Questions about Marcel Thalen

What company does Marcel Thalen work for?

Marcel Thalen works for Biolyo Technologies

What is Marcel Thalen's role at the current company?

Marcel Thalen's current role is CEO at BioLyo Technologies.

What is Marcel Thalen's email address?

Marcel Thalen's email address is m_****@****hoo.com

What is Marcel Thalen's direct phone number?

Marcel Thalen's direct phone number is +195433*****

What schools did Marcel Thalen attend?

Marcel Thalen attended Wageningen University & Research, Wageningen University & Research.

What skills is Marcel Thalen known for?

Marcel Thalen has skills like Biotechnology, Life Sciences, Vaccines, Fermentation, Microbiology, Research, Cell Culture, Biochemistry, Science, R&d, Lifesciences, Gmp.

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