Marcela González Granillo, Msc Phd Email & Phone Number

Stockholm County, Sweden

Stockholm, Stockholm County, Sweden

✓ Actively participate in cross-functional Virtual Plant Team, collaborating across Drug Substance (DS), Drug Product (DP), and Contract Lab Operations (CLO).✓ Manage coordination of shipments and logistics to ensure timely and accurate delivery.✓ Lead and coordinate Change Controls and Deviations, maintaining compliance with regulatory standards.✓ Support Quality Assurance by migrating records to new QA systems, optimizing data integrity and accessibility.✓ Participate in key meetings with Contract Manufacturing Organizations (CMO) and Contract Lab Operations (CLO).✓ Conduct DS and DP allocations and calculations, enhancing inventory and production accuracy.✓ Direct internal activities in external manufacturing, including change management, deviations, and CAPAs.✓ Issue and reviewe Standard Operating Procedures (SOPs) and manufacturing instructions to uphold quality standards.✓ Spearhead or contribute to continuous improvement projects, driving efficiency both internally and with external partners.✓ Facilitate administrative tasks, including quote submissions and purchase order creation.

Stockholm, Stockholm County, Sweden

Working at Sobi in the Global Manufacturing & Supply (GMS) division, within the External Drug Substance (DS) / Drug Product (DP) Manufacturing department.

Solna, Stockholm County, Sweden

✓ Inaugurating the New Manufacturing Wet Lab Unit:Spearheading the establishment of a cutting-edge manufacturing wet lab unit, overseeing operations, and orchestrating the procurement of essential consumables.✓ Standardizing Manufacturing Protocols:Crafting meticulous manufacturing protocols by extrapolating from R&D advancements. This endeavor aims to facilitate seamless technology transfer and fortify Pixelgen's commitment to a reliable customer supply✓ Optimizing Product Logistics:Cultivating strategic partnerships with suppliers to design Pixelgen kit reagent boxes with a focus on high-quality labeling for easy component identification. Overseeing the logistics of shipping components, ensuring precise temperature control throughout the Pixelgen kit distribution chain.✓ Quality Control Procedures and Documentation:Instituting rigorous Quality Control (Q.C.) procedures for both incoming supplies and the production of reagents. Rigorously maintaining comprehensive documentation to uphold stringent quality standards.✓ Budget Forecasting for Manufacturing Department:Undertaking meticulous budget forecasting for the manufacturing department to enhance resource allocation and streamline operational efficiency.✓ Facilitating Product Transfer and Stability Studies:Orchestrating the seamless transition of products from R&D to Manufacturing. Conducting rigorous stability studies for kit components to ascertain sustained efficacy over time

Uppsala, Uppsala County, Sweden

✓ Client Engagement Throughout the Product Lifecycle:Establishing a close and continuous relationship with the customer, starting from the early stages of designing fit-for-purpose panels and extending through to product delivery.✓ Analytical Validation of Clinical Biomarkers:Conducting thorough analytical validation of clinical biomarkers to ensure accuracy and reliability.✓ Laboratory Protocol Restructuring for Global Expansion:Taking a hands-on approach in restructuring laboratory protocols and practices, facilitating technology transfer, and ensuring the seamless global expansion of Olink.✓ Scalability and Optimization of Customized Products:Spearheading the scalability and optimization efforts for customized products, leveraging existing Proximity Extension Assay technology to enhance efficiency.

Uppsala County, Sweden

★ Daily Resource Management in the COVID-19 Lab:✓ Overseeing day-to-day resource management encompassing personnel, technology, and consumables to ensure smooth operations in the laboratory.✓ Personnel: Communicating resource needs to the staff manager for optimal workflow, enhancing efficiency in laboratory operations.✓ Technology: Collaborating with the technology department by providing input on instrument or assay issues and advocating for additional technology resources, thereby improving efficiency and reducing delivery times.✓ Consumables: Managing inventory and coordinating with purchasing to place orders for supplies, preventing disruptions in delivering results to customers.★ Communication with COO for Additional Resources:✓ Informing the Chief Operating Officer (COO) about the need for additional resources and offering insights into the lab's capacity and customer compliance. This proactive approach ensures continuous improvement in lab capabilities and adherence to customer requirements.

Uppsala, Uppsala County, Sweden

✓ Laboratory Practices and Safety Protocols in Biosafety Level III Lab (GLP, GMP):Overseeing the organization of laboratory practices and safety protocols in a biosafety level class III lab, adhering to Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP), particularly in the processing of human fluid samples.✓ Implementation of Inventory System:Establishing and structuring an efficient inventory system within the company to optimize resource management and streamline operations.✓ Daily Tracking of Consumables and Product Movement:Maintaining a daily record of consumables and product movement to align team efforts with customer needs, contributing significantly to the company's strength and growth.✓ Organizing and Coordinating Laboratory Members:Orchestrating, coordinating, and scheduling laboratory members to ensure seamless workflow and productivity.✓ GDPR Compliance and Documentation:Ensuring compliance with GDPR regulations and crafting Standard Operating Procedures (SOPs), reports, and technical documents for Quality Control (QC) processes.✓ Assay Optimization for COVID-19 Diagnosis:Demonstrating a firm dedication to the team by optimizing assays, enabling a scalable and efficient diagnosis of COVID-19, with a remarkable capacity of approximately 2000 diagnoses per day.

Huddinge, Stockholm County, Sweden

Professional Development in Mentoring and Communication as Postdoctoral Researcher, Department of Medicine, Huddinge - ICMC. Project: Epigenomic Effects of Mother's Diet on Offspring Metabolism✓ Expert Communication of Complex Topics:Proficiently communicated intricate subjects to diverse audiences, evidenced by seven scientific presentations, including a talk and six posters. Complemented by a published paper, showcasing a capacity to convey complex ideas effectively.✓ Leadership in Pre-Clinical Research Projects:Spearheaded pre-clinical research endeavors focused on the therapeutic approach to obesity and associated diseases. Employed advanced methodologies such as functional genomics, in vivo and in vitro models, and various analytical techniques, encompassing molecular, cellular, and cutting-edge imaging modalities like Microscopy and MRI-MRS.✓ Effective Group Meeting Coordination:Skillfully coordinated group meetings, fostering a collaborative environment and facilitating knowledge exchange among team members engaged in the Epigenomic Effects project.✓ Mentoring Excellence for Student Projects:Played a central role in mentoring master and bachelor students, providing guidance for their projects and contributing significantly to their academic and research advancement.

Stockholm, Sweden

Leadership Skills Developed During Principal Investigator Sabbatical Year, Department of Medicine - ICMC✓ Effective Management of Collaborative Research Projects:Successfully led and managed a team of research professionals in collaborative projects, fostering international partnerships with Portugal and the USA. This collaborative effort resulted in two publications, with one as the corresponding author, demonstrating effective project leadership.✓ Lecturer in Human Nutrition Course at Karolinska Institute:Contributed expertise as a lecturer in the Human Nutrition course at the prestigious Karolinska Institute, showcasing the ability to convey knowledge and insights to students.✓ Dynamic Presentation of Research Findings:Conducted both internal and external presentations, showcasing our research in the field of metabolism to professionals. This included engaging presentations to both internal teams and external experts, highlighting effective communication skills and the ability to disseminate research outcomes.

Huddinge, Stockholm County, Sweden

Project Management Expertise Developed as Postdoctoral Research Fellow, Department of Biosciences and Nutrition. Projects: Characterization of ERβ activation by a synthetic ligand during Obesity | Gender-Specific Response towards Obesity✓ Holistic Project Leadership:Led both pre-clinical projects with responsibility for planning, organization, and effective teamwork, showcasing strong project management and collaboration skills.✓ Diverse Analytical Proficiency:Demonstrated proficiency in utilizing a wide array of analytical tools, employing in vivo and in vitro models, as well as molecular, cellular, and imaging techniques.✓ Publication and Presentation Achievements:Contributed to the field with three published works, delivered three talks, and presented six posters, highlighting a comprehensive understanding of the subject matter and effective communication skills.✓ Expertise in Scientific Data Analysis:Applied knowledge and experience in analyzing large scientific datasets, resulting in meaningful contributions to the literature and advancements in understanding the projects.✓ Integration of Techniques for Comprehensive Understanding:Applied a combination of physiologic, metabolic, and genetic techniques, providing an integral overview and understanding of the therapeutic effects in the context of the projects.

Stockholm, Sweden

Innovative Postdoctoral Fellow at the Department of Clinical Science, Intervention and Technology (CLINTEC) Project: Characterization of Tendon Biology and Pathology✓ Innovative Protocol Development:Pioneered the development of a novel protocol using mesenchymal stem cells, demonstrating innovation in differentiating them into tenocytes for the advancement of tendon biology research.✓ Biological Degradation Process for Soft Tissue Adhesive:Led the development and evaluation of the biological degradation process for a biomaterial soft tissue adhesive in collaboration with KTH, resulting in a significant contribution to the field with one publication.✓ Cross-Functional Collaboration and Relationship Building:Established and nurtured cross-functional collaboration with clinics, facilitating the collection of bone marrow and injured-tendon samples. Applied diverse molecular and cellular techniques to study these samples further, showcasing excellent relationship-building skills and a commitment to advancing research through collaborative efforts.

Grenoble Area, France

✓ Versatility Demonstrated Through Ph.D. Journey in a Multicultural Environment:Showcased adaptability by initiating my Ph.D. in a new country, culture, and language, thriving in a multicultural environment.✓ Effective Project Management in Cardiac Muscle Cells:Functioned as a project manager, conducting studies on the structure-function relationship in the regulation of compartmentalized energy metabolism in cardiac muscle cells.✓ Information Management and Rapid Learning of Precision Techniques:Exhibited information management skills and quick learning abilities, mastering high-precision techniques such as isolated heart perfusion at Langerdorff system, respiratory activity measurements by oxygraphy, immunofluorescence in isolated-fixed cardiomyocytes, and transfection of isolated cardiomyocytes.✓ Attention to Detail in Specialized Imaging:Demonstrated meticulous attention to detail and a driven approach in utilizing highly specialized imaging equipment for in vivo-in situ and in vitro-in situ scanning of cardiomyocytes and cardiac tissue. Analyzed mitochondrial movements and localization to generate movies and 3D images.✓ Effective Communication, Teamwork, and Collaboration:Leveraged strong communication skills, teamwork, and collaboration to meet deadlines and explore the mechanisms controlling energy fluxes and the role of structure-function relationships in metabolic regulation.✓ Innovation and Creative Problem Solving:Exhibited innovation and creative problem-solving skills by discovering a specific distribution of beta-tubulin isotypes in healthy adult cardiomyocytes, influencing energy metabolism regulation.✓ Professional Awareness Through Global Presentations and Publications:Demonstrated professional awareness by presenting work at three international and three national meetings and publishing six articles in recognized international journals, contributing significantly to the scientific community.

Mexico City Area, Mexico

✓ Patient-Centered Relationship Building and Organizational Skills:Established strong patient relationships through nutritional assessments, fostering patient commitment to treatment plans. Demonstrated organizational prowess in ensuring effective nutritional care.✓ Effective Communication to General Public:Utilized effective communication skills in delivering several talks to the general public, educating them about nutrition and its profound effects on overall health status.

Stockholm, Sweden

★ Proficiency in Cellular and In Vivo Research:✓ Demonstrated advanced expertise in utilizing immortal cell lines, specifically HepG2 and HuH7 cells, highlighting proficiency in cell-based research.★ In-Depth In Vivo Metabolism Studies:✓ Applied sophisticated in vivo models to meticulously study metabolism, employing longitudinal tests such as Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT). Contributed significantly to advancing our understanding of metabolic dynamics.★ Mastery of Molecular Techniques:✓ Showcased a high level of proficiency in diverse molecular techniques, including:✓ Precision in RNA extraction to ensure top-tier genetic material for subsequent analyses.✓ Skillful implementation of qPCR (quantitative Polymerase Chain Reaction) for accurate quantification of gene expression levels.✓ Conducted luciferase assays, a sophisticated method for in-depth exploration of gene regulation and expression.✓ Expertise in transfections and co-transfections, illustrating a command of manipulating genetic material within cellular systems.

Project Management Master, Digital Project Manager, Certified

A Master program that includes the following main courses: - PMP : Project Management Professional - PDU 35h - Agile Scrum Master (ASM).

Phd, Bioenergetics

Activities and Societies: Biochemical Society | American Society for Cell BiologyDoctoral Thesis: Molecular System Bioenergetics of Muscle.

Master Of Science - Ms, Biochemistry

Activities and Societies: FASEB societyMaster thesis: Regulation of the bile acids metabolism by soy protein through LXRalpha, at Inst..

Bachelor, Nutrition And Food Science

Clinical Nutrition background and field practice Food Science: Regulation | HACCP | Microbiology Undergraduate thesis (2005-2006): Effect.