Mareike Hoffmann Email & Phone Number

Heidelberg, Baden-Württemberg, Germany

Minneapolis, Minnesota, United States

As a postdoctoral associate at the University of Minnesota, I investigate the extent to which domain insertions in the AAV capsid can redirect viral cell tropism and I supervise the day-to-day experimental work of graduate students. Furthermore, I am involved in an industrial collaboration for which I design and produce AAV vectors.

Heidelberg Area, Germany

In my postdoc time at the University Hospital Heidelberg, I designed and optimized AAV vector DNA for cell type-specific gene therapy targeting and subsequently validated them in vivo in mice. I was also responsible for performing neutralizing AAV antibody screenings for industry collaboration partners.

Heidelberg Area, Germany

During my PhD I engineered light- and microRNA-dependent anti-CRISPR proteins for a conditional activation of CRISPR-Cas9 enzymes. Following a 3-year stipend from the German Cancer Research Center (DKFZ), I graduated in December 2019 and obtained my Dr. rer. nat. with summa cum laude from the University of Heidelberg.

Heidelberg, Baden-Württemberg, Germany

Successfully supervised the students team Heidelberg in the iGEM competition 2017 resulting in the 2nd runner up and 6 special prizes.

Dortmund, North Rhine-Westphalia, Germany

Learned protein purification and investigated the protein-protein interaction between SMAD3 and 14-3-3.

Philadelphia, Pennsylvania, United States

Explored the molecular link between hypoxia and glucose metabolism practicing standard molecular biology skills including cloning, DNA/RNA isolation, and RT-PCR.

Essen, North Rhine-Westphalia, Germany

Leader of a chemistry tutorial for first semester students in Medical Biology, discussing weekly exercises and preparing the students for the final exam.

Doctor Of Philosophy - Phd, Molecular Biology

Master Of Science - Ms, Medical Biology

Bachelor Of Science - Bs, Medical Biology