Maria De Mieri

Maria De Mieri Email and Phone Number

Team Leader Analytical Development and Validation @ Syngenta
basel, basel-city, switzerland
Maria De Mieri's Location
Azzate, Lombardy, Italy, Italy
Maria De Mieri's Contact Details

Maria De Mieri personal email

About Maria De Mieri

I am a passionate, hardworking chemist with 11 years of experience in the chemistry of small organic molecules, in either academia and industry. I’ve started my career in the field of enzymatic and organic synthesis, with a strong focus on method development for purification, analysis and structural elucidation of biologically active molecules by LC-PDA/ELSD/MS, GC-MS, NMR and IR. Later on, I’ve been responsible for the NMR-structure elucidation laboratory at the Pharmazentrum (University of Basel, CH), working on the isolation and structure elucidation of natural products from plants. Since December 2016 I’ve joined Syngenta AG, (Munchwilen, CH) as team leader in the analytical development and product chemistry department, where I am leading a team of 5 analysts. My daily job consists in all analytical activities required to develop, register and commercialize products with herbicidal activity. Alongside to my current position, I am collaborating as reviewer of scientific journals and I am always interested in new scientific innovations.

Maria De Mieri's Current Company Details
Syngenta

Syngenta

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Team Leader Analytical Development and Validation
basel, basel-city, switzerland
Website:
syngenta.com
Employees:
25828
Maria De Mieri Work Experience Details
  • Syngenta
    Team Leader Analytical Development
    Syngenta May 2017 - Present
    Switzerland
    • Leading in a cost effective way a team of 5 analysts • Developing and optimizing together with my team analytical methods for the determination of the assay, level of impurities and stability of active substances, formulations, and raw materials • Qualified as GLP Study Director • Generating analytical data - following GLP (Good Laboratory Practice) – and issuing documents in support of the registration of active substances and formulations (e.g. leading the “quality strategy” for new active substances to issuing the registration specification) • Providing global support for requests related to the assessment and sustainability of the quality during the whole life-cycle of 10 herbicides (e.g. analysis of generic and/or counterfeit products) • Providing business benefit, through scientific and technical innovation in the area of analytical chemistry and measurement science (establishment of a 2D-LC heart-cutting platform for peak purity assessment)
  • Micro-Sphere Sa
    Qc - As&T Team Leader
    Micro-Sphere Sa Apr 2022 - Present
    Monteggio, Switzerland
    • To lead the AS&T group and ensures the development of the team members in technical and leadership skills while maintaining a good communication culture within the team • To lead the development and validation according to ICH and GMP guidelines analytical methods for the determination of the assay, level of impurities and stability of APIs, formulations and raw materials • To lead the development and validation of analytical methods for cleaning verification • To perform qualification of computerized systems (CSV) • To support the introduction of new projects by discussing with clients on the analytical aspects and requirements • To outsource analytical activities to CROs • To evaluate and implement new technologies required to maintain state-of-the-art analytical methods for development and market products • To prepare and participate in quality audits
  • Syngenta
    Analytical Development
    Syngenta Dec 2016 - Mar 2017
    Munchwilen, Switzerland
    -Development and optimization of analytical methods for the determination of the assay, level of impurities and stability of active substances, formulations, and raw materials-Analytical Characterization and re-analysis of chemical substances and formulation under GLP-Validation of analytical methods and instrumentation under GLP
  • University Of Basel, Switzerland
    Post-Doc In Charge For The Nmr Laboratory
    University Of Basel, Switzerland Apr 2012 - Nov 2016
    Http://Www.Pharma.Unibas.Ch/Index.Php?Id=Institutes&Subid=Pharmaceuticalbiology
    • Responsible for the NMR-structure elucidation laboratory (BRUKER AV III 500 MHz overall maintenance) • PhDs and MSc students (12) supervision and training on natural product isolation (PDA/ELSD/MS-HPLC, GC-MS/MS) and identification from natural extracts by NMR (more than 200 identified compounds) • Semi-synthesis of natural-products derived bioactive compounds • Conformational analysis and ECD calculation for absolute configuration assignment • Writing of publication for peer-reviewed international journals • Presentation of research projects to national and international chemistry conference.
  • Università Degli Studi Di Milano, Euticals
    Postdoctoral Fellow
    Università Degli Studi Di Milano, Euticals Feb 2011 - Mar 2012
    Milan, Italy
    Projects Synthesis of compounds with anti-Parkinson activity through biotransformationsTasks• Biocatalyzed reactions (with purified enzymes and yeasts) planning and execution at lab scale• Synthetic reactions planning and execution at lab scale• Organic compounds purification (flash chromatography, HPLC on reverse and chiral phases)• Compounds characterization by NMR, MS, PDA-HPLC, GC, optical rotation• Supervision of one MSc student in practical laboratory work
  • Universitè Laval, Quebec, Canada
    Phd Visiting Student
    Universitè Laval, Quebec, Canada Sep 2009 - Jul 2010
    Quebec City, Canada
    Project:Synthesis of amidotransferase inhibitors related to chloramphenicol, Supervised by Prof. Robert Chênevert.Tasks:• Optimization of enantioselective synthesis• Resolution of racemates through lipases catalyzed reactions• Development of HPLC separation on chiral phases
  • Università Vita-Salute San Raffaele Milano
    Teaching Associate Professional
    Università Vita-Salute San Raffaele Milano Oct 2008 - Jan 2009
    Milan, Italy
    Task:Practical training for the course of "Chemistry and Biochemistry", MSc in Medicine, 1st year
  • Università Degli Studi Di Milano, Cosmo Pharmaceuticals
    Grant Recipient
    Università Degli Studi Di Milano, Cosmo Pharmaceuticals Apr 2007 - Oct 2007
    Milan, Italy
    Project:Derivatives of cortexolone with antiandrogen activity: synthesis, purification and development of analytical methodologies.

Maria De Mieri Skills

Purification By Chromatography Of Organic Molecules Execution And Interpretation Of 1d And 2d Nmr Experiments Determination Of The Impurity Profile Of Drugs Risonanza Magnetica Nucleare Chimica Hplc Biochimica Medicinal Chemistry Analytical Methods Development Purificazione Caratterizzazione Laboratorio Gascromatografia Laboratory Skills Chemistry Scienza Sintesi Organica

Maria De Mieri Education Details

Frequently Asked Questions about Maria De Mieri

What company does Maria De Mieri work for?

Maria De Mieri works for Syngenta

What is Maria De Mieri's role at the current company?

Maria De Mieri's current role is Team Leader Analytical Development and Validation.

What is Maria De Mieri's email address?

Maria De Mieri's email address is ma****@****ail.com

What schools did Maria De Mieri attend?

Maria De Mieri attended Università Degli Studi Di Milano, Università Degli Studi Di Milano.

What are some of Maria De Mieri's interests?

Maria De Mieri has interest in To Read, Children, To Travel, To Cook.

What skills is Maria De Mieri known for?

Maria De Mieri has skills like Purification By Chromatography Of Organic Molecules, Execution And Interpretation Of 1d And 2d Nmr Experiments, Determination Of The Impurity Profile Of Drugs, Risonanza Magnetica Nucleare, Chimica, Hplc, Biochimica, Medicinal Chemistry, Analytical Methods Development, Purificazione, Caratterizzazione, Laboratorio.

Who are Maria De Mieri's colleagues?

Maria De Mieri's colleagues are Courtney Holdt, Numan Ejaz, Sibu Dutta, Simone Aramaki, Mustafa Alper Köseli, Peter Campbell, Rogers Inacio.

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