Marieve Dupuis Email & Phone Number

Canada

Montreal, Canada Area

Responsible for PK and PK/PD analyses and reporting using state-of-the-art methods and software. Performs noncompartmental and compartmental PK/PD modeling in various phases of drug development.Performs PK/PD modeling, dose-reponse modeling and statistical analyses according to state-of-the-art methods and regulatory requirements. Collaborate with a team.

Montréal

• Review clinical and bioanalytical data, perform PK analyses, interpret results and incorporate the findings in high quality reports for FDA, EMA, Health Canada or ANVISA.
• Participation in the review process of new protocols to ensure that the study plans will allow achievement of PK objectives and to ensure general scientific quality.
• Author of statistical analysis plan in collaboration with biostatisticians.
• Participation in the generation of new template with Phoenix®… Show more
• Participation in the generation of new template with Phoenix® WinNonlinTM for generation of PK tables and figures for rapid generation of high quality reports, improving timing metrics for clinical pharmacology.
• Responsible of practical training sessions for peer colleagues on Phoenix® WinNonlinTM.

• Drug Discovery Support, Biological Sciences,Boehringer Ingelheim Canada Ltd
• Planned and executed all surgical procedures required for oral and intravenous automated pharmacokinetic (PK) studies in rodents. Performed raw data analysis, calculation of PK parameters and reported results to.
• Performed and taught various cannulation techniques in rodents (carotid, jugular vein and common bile… Show more Drug Discovery Support, Biological Sciences,Boehringer Ingelheim Canada Ltd
• Performed and taught various cannulation techniques in rodents (carotid, jugular vein and common bile duct).
• Evaluated, validated and recommended an automated PK samplers model allowing unattended sampling, leading to improved data quality, reduced animal stress and number study repeat improving efficiency of lead.
• Established a micro-sampling technique in mice to improve data quality and reduce number of animals (full profile per animal). Participated to the redaction and/or revision of SOPs (rodent surgeries and post approval.

Master'S Degree, Pharmacology

Master Degree, Pharmacology

Role of the NADPH-reductase in the diminution of CYP3A6 during an inflammatory reaction Rabbit hepatocytes isolation (primary culture)..

Bachelor Degree, Biomedicals Sciences