Marion Hoffmann Email & Phone Number

Basel, Bs, Ch

Basel, Switzerland

- Planning, execution and reporting of long-term stability, freeze/thaw, in-use, and forced degradation studies- Responsible for inter- and intra-company analytical method transfers- Coordination of analytical activities for client projects

Basel, Switzerland

QC activities: - Review of analytical raw data, preparation of specifications, sampling plans, batch records, and COAs AD activities: - Development and optimization of CE methods, generation of SOPs and form sheets- Authoring and review of feasibility, development, qualification, and validation documents- Coordination of analytical activities for client projects from process development to GMP release

Edmonton, Canada

Department of Physics, Woodside labMisfolding and aggregation of alpha-synuclein: Design, cloning, and purification of tandem constructs; biophysical characterization of the native state, early oligomers, and aggregated states.

Lethbridge, Canada

Department of Chemistry and Biochemistry, Wieden labRole of the universally conserved protein YchF in ribosome function: Purification of YchF, bacterial ribosomes and RNAs; identification of interaction partners, characterization of binding modes, and effects on enzymatic activity.

Potsdam, Germany

Institute of Biology and Biochemistry, Seckler labSide chain stacking in the P22 tailspike protein β-helix: Design and production of 20+ protein variants; biochemical and biophysical characterization of in vivo and in vitro protein stability and folding.

Berlin Und Umgebung, Deutschland

Macromolecular Structure and Interaction, Heinemann labCrystallography and X-ray structure determination of P22 tailspike protein variants.

Witten/Herdecke, Germany

Institute for Physical Biochemistry, Rodnina labRole of the elongation factor Tu in ribosome function: purification of protein variants; biochemical and kinetic characterization of the interaction with bacterial ribosomes and tRNAs.

Cambridge, Großbritannien

Department of Biochemistry, Paoli labProduction and characterization of NF-kappaB variants.

Dr. Rer. Nat., Physical Biochemistry

„Bedeutung eines hydrophoben Seitenkettenstapels für Stabilität, Faltung und Struktur des P22 Tailspikeproteins“, November 2009

Diplom, Biochemistry

„GTPase activation of elongation factor Tu on the ribosome: role of residues Arg58 and His66“, April 2004

Vordiplom, Biology