Marion Philippe Email & Phone Number

Région De Toulouse, France

In charge of in vitro Immuno-oncology assay development to evaluate therapeutic candidates, from the protocol design and technical thinking to the analysis of the results and the communication to the clients.Currently involved in the implementation of a drug discovery shedding platformProcess optimization (automation and miniaturization)Management of human cells banking.Flow cytometry, ELISA, in vitro assays (proliferation, apoptosis, cytotoxicity, immunophenotyping, shedding assays, cell transfection and transduction, etc.)

Toulouse, Occitanie, France

Co-Leading a LEAN project (Yellow Belt Lean Six Sigma certification) on the implementation of sorting bins and waste management in Toulouse site by using LEAN SIGMA tools project planning, survey creation and analysis, pilot study, root cause analysis by using 5 why and fishbone tools, improvement and control stepsGlobal sustainability continuous improvement participation and communication for all EVOTEC sites.

Paris, France

Development and evaluation of pre-clinical immuno-oncology therapeutic candidates In charge of in-vitro assays development (cytotoxicity, proliferation, immunophenotyping)Immunomonitoring and evaluation of in vitro /in vivo cytotoxicity and anti-tumor efficacyManagement of cell culture and flow cytometry platforms (banking, phenotyping)Protocol design, realization and study follow-up of preclinical pharmacology studiesQA, regulatory documents and poster writing Animal experimentation, DNA vaccine, tumor models (subcutaneous / IV implantations) Immunomonitoring (IFNg and GRB ELISpots, ELISA, FACS, in vitro and in vivo cytotoxicity assays)

Paris, France

In charge of humanized mice model development using human hematopoietic progenitor cells for immunotherapies evaluationDevelopment of patient derived xenograft (PDX) melanoma panelDevelopment of murine breast and melanomas xenograft modelsTests of therapeutic monoclonal antibodiesStudy design, protocol writing, study follow-up of immunotherapy efficacyCell culture, ELISA, FACSIn vivo bioluminescenceExperimentations on human samples (tissues and blood)Collaboration with OREGA Biotech

Rennes, France

Development of in vitro and in vivo glioblastoma preclinical models Subcutaneous and intracerebral xenograft in immunodeficient mouse modelIn vivo pharmacological tests, surgeries in rodents, stereotaxyMRI, in vivo bioluminescenceCell culture, cytotoxicity, proliferation and clonogenicity assays Collaboration with Translational group Oncology

Vancouver, Canada

Sudy of Impact of neuronal leptin receptor attenuation on mice fed with high fat diet and low fat diet ADN and ARN extraction, PCR, RT-PCR, Immunochemistry

Université François Rabelais, Ufr De Pharmacie De Tours

Study of cerebral metabolism of Attention Deficit Hyperactivity Disorder (ADHD) animal models by scintigraphic imagingPositron Emission Tomography (PET)HPLC analysis

Z.A. De Glatigné, 53940 Le Genest Saint Isle

Study of Fluoxetine and Paroxetine withdrawal in ratsPharmacological tests Telemetry

Pôle Biologie Santé, Poitiers

Neurobiological studies of abuse drugs addiction, and reversibility of cognitive deficits induced by psychostimulants in enriched environments

Yellow Belt Lean Six Sigma, Continuous Improvement

Professional Master'S Degree, "Recherche Et Ingénierie En Biosanté, Spécialité Génie Cellulaire"

Bachelor'S Degree, Animal Physiology And Neurosciences

Diplome Universitaire Technologique, Analyses Biologiques Et Biochimiques

Habilitation À L'Experimentation Animale De Niveau 2, Zoologie / Biologie Animale