Mario Vieweger Email & Phone Number

Woodridge, Il, Us

Aachen, De

Exeter, Devon, Gb

Consulting on biotech startup strategy, oligonucleotide therapeutics, platform discovery and drug discovery.

Cambridge, Massachusetts, Us

Chicago, Illinois, Us

Team Lead for R&D discovery. • Subject matter expert (SME) for oligonucleotide chemistry. • Cross-functional process development and implementation. • R&D operations and workflow development and integration. • Drug discovery supervision and process standardization.

Chicago, Illinois, Us

Team Lead for platform discovery. • Subject matter expert (SME) for oligonucleotide chemistry. • SAR studies in oligonucleotide therapeutics and SNA delivery. • Process improvements in oligo production, quality control and in vitro screening. • New modalities and therapeutic platforms.

Chicago, Illinois, Us

Lead scientist in oligonucleotide chemistry. • Subject matter expert (SME) for oligonucleotide chemistry. • Method development in oligonucleotide production, purification and characterization. • Process development for new oligonucleotide modalities.

Columbus, Ohio, Us

Business operations and development for biotech and oligo therapeutics products. • Led growth of a biotech startup from installing the first lab to mid 6-figures in Year 2. • Managed business operations and strategy from product development to commercialization of two first-to-market biotech product lines. • Established standard operating procedures (SOPs) for oligo production, purification, and quality control of therapeutic oligonucleotides. • Managed development programs with external partners. • Managed sales programs as CDMO. • Led sales projects and customer support for key accounts. • Managed IP, legal, HR, compliance, licensing, and accounting with external stakeholders.

Columbus, Ohio, Us

Platform development for targeted delivery of oligonucleotide therapeutics.• Led research teams in development of targeted drug delivery platforms for oligo therapeutics and small chemicals. • Filed two technology patent that received licensing agreements and 7-figure angel-funding for an oligo therapeutics startup.• Managed operations of a 20-member research team with $3M capital equipment and $10M in external research funding.• Organized conferences, IP filings, grant applications, budgets, and an NIH site visit.

Lexington, Ky, Us

Platform development for targeted delivery of oligonucleotide therapeutics.• Designed and developed drug delivery platforms based on micelle, dendrimer and nanoparticle technologies.• Established protocols for oligo modification, bioconjugation, and purification to optimize oligo hybridization and ligand binding affinities. • Developed assays for in vitro characterization of physical parameters, stability, duplex formation and degradation.

Boulder, Colorado, Us

Antisense inhibition of viral gene expression. • Developed biochemical and biophysical assays to study structure activity relationships (SAR) affecting viral gene expression.• Designed antisense oligonucleotides for inhibition of viral gene expression. • Established procedures for synthesis, conjugation, purification and activity screening of oligonucleotide inhibitors.

Bloomington, Indiana, Us

Structure activity relationships of organic and bio-inorganic probes. • Developed assays to screen capsid assembly of virus-like nanoparticles. • Development a microscopy technique for imaging and tracking of single virus-like nanoparticles. • Elucidated structure activity relationships (SAR) of a series of organic molecules using fluorescence assays to improve ligand binding affinity.

Mba, Master Of Business Administration

Phd, Physical Chemistry

B.S.(Equiv.), Chemistry