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Mark Bures is listed as Molecular Modeling and Computational Chemistry Practitioner at Self-employed, based in Zionsville, Indiana, United States. AeroLeads shows a work email signal at silicontx.com and a matched LinkedIn profile for Mark Bures.
Mark Bures previously worked as Molecular Modeling and Computational Chemistry Consultant at Self-Employed and Director of Modeling and Simulations at Silicon Therapeutics. Mark Bures holds Ph.D., Organic Chemistry from Purdue University.
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Accomplished molecule designer responsible for supporting and leading cross-functional teams delivering multiple LG, LO and candidate milestones.Specialties: drug design, computational chemistry, molecular modeling, structure-based drug design, target assessment, diabetes and antiviral research, cheminformatics, six sigma and lean, cross-functional team leadership
Listed skills include Drug Design, Cheminformatics, Drug Discovery, Computational Chemistry, and 44 others.
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Partners include four biotechnology companies. Contributions include hit identification and optimization for new drug discovery projects, designing novel scaffolds for multiple efforts, triaging an HTS and selection of best starting points, data analyses for drug discovery projects, helping a start-up get off the ground.
Led design teams and worked with chemistry leads to prioritize compounds for synthesis. Implementation and optimization of design cycle processes. Used structure-based design to deliver drug-like ligands for several portfolio projects. Defined and led hit-finding campaigns to find new starting points for several drug discovery efforts. Carried out multi-faceted target druggability assessments, to help select targets for portfolio entry. Supervision, mentoring and coaching of group members. Provided organizational scientific strategy through interactions with leadership and management teams. Project lead for a drug discovery effort, responsible for setting strategy and directing a multi-disciplinary team.
South San Francisco, California, Us
Responsible for the application of molecular design and computational chemistry to help teams achieve drug discovery milestones. Extensive experience in structure- and property-based drug design, from ideation through drug candidate selection. Co-inventor of three clinical compounds.
Indianapolis, Indiana, Us
Highly skilled in iterative structure/fragment-based ligand design and directing the syntheses of drug-like compounds, using both internal and external resources. Led a computational chemistry collaboration with an external service provider. Responsible for deciding and directing the LG activities of seven external scientists.
Indianapolis, Indiana, Us
Certified Six Sigma and Lean black belt. Led the Discovery Six Sigma Task Force, responsible for vetting new project ideas.
Indianapolis, Indiana, Us
Supervised three research scientists. Extensive experience in developing GPCR protein-structure models that were used prospectively to help design two clinical candidate molecules.
Abbott Park, Illinois, Us
Part of the team that developed the DISCO pharmacophore mapping program, distributed by Tripos.
Abbott Park, Illinois, Us
Part of the team that discovered Ritonavir, one of the first marketed HIV protease inhibitors.
Abbott Park, Illinois, Us
Supported LG and LO efforts, including developing new tools for pharmacophore exploration.
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Mark Bures works for Self-employed.
Mark Bures is listed as Molecular Modeling and Computational Chemistry Practitioner at Self-employed.
AeroLeads has found 1 work email signal at @silicontx.com for Mark Bures at Self-employed.
Mark Bures is based in Zionsville, Indiana, United States while working with Self-employed.
Mark Bures has worked for Self-Employed, Silicon Therapeutics, Assembly Biosciences, Eli Lilly, and Abbott Laboratories.
You can use AeroLeads to view verified contact signals for Mark Bures at Self-employed, including work email, phone, and LinkedIn data when available.
Mark Bures holds Ph.D., Organic Chemistry from Purdue University.
Mark Bures is listed with skills including Drug Design, Cheminformatics, Drug Discovery, Computational Chemistry, Molecular Modeling, Chemistry, Organic Chemistry, and Medicinal Chemistry.
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