Mark Cradduck Email & Phone Number

Omaha, Nebraska, United States

Innovate, formulate new products, process scale-up, and manufacturing support of multiple pet care product lines. Reduce production costs and improve efficiency of existing pet care products. Adhere to applicable EPA and FDA policies and procedures.

Lincoln, Nebraska, United States

- Headed a team responsible for process development and manufacturing of a NIR dye, and within 6 months increased the reaction yield over 200% and increased the manufacturing scale by over 500 times.- Chief technical advisor for the transfer of intellectual property. Responsibilities included written reports, raw data transfers ensuring data integrity, meetings, and international travel to observe and assist chemical processes.- Identified and helped source large-scale process equipment in order to increase production capacity.

Lincoln, Nebraska, United States

Planned and conducted organic synthesis, analytical method development, process development, and process scale-up of NIR fluorescent dye reagents for use in research and clinical markets. Co-led the manufacturing team for kilo-scale production of a NIR dye within a GMP regulated environment. Performed impurity analysis, structural elucidation, and manufactured product reference standards. Synthesized custom silanes and siloxanes used to investigate dye process improvement and modifying glass surfaces and silica particles toward the binding of proteins and polymers. Collaborated with the Quality and Supply Chain teams evaluating chemical vendors to ensure critical quality attributes and delivery timelines. Coauthored requests for proposals and tech transfer reports to guide the sourcing of key starting materials from multiple CRO/CMO’s.

Lincoln, Nebraska, United States

Performed multistep organic synthesis, product purification, and analytical method development of near-infrared (NIR) fluorescent dyes (cyanine & phthalocyanine), quenchers, dye-labeled polymers, and related starting materials. Utilized HPLC, LC-MS, NMR, UV-Vis, and Fluorescence spectroscopy to characterize products, intermediates, and impurities. Authored standard operating procedures (SOP) for product manufacturing and analytical release testing. Performed tech transfer of SOP's to the Reagent Production and QC teams in accordance with ISO 9001 quality practices.

Bachelor Of Science - Bs, Chemistry

All M.S. Graduate Courses Completed, Organic Chemistry