Mark Eagle Email & Phone Number

Current scientific development for R&D department of Tissue and Eye Services within the NHS Blood & Transplant. Developing new and existing human tissue allografts supplied to patients from NHS Blood & Transplant to either improve or save patients lives, and improve tissue safety. Examples of tissues supplied include bone, cartilage, skin, tendon, heart valves, cornea and amnion.Development and testing of processes, for example to demineralise cortical/cancellous bone and decellularisation of pulmonary vessel patches.Extensive knowledge and experience of tissue dissection and human anatomy, with working knowledge of ethics and HTA regulations. Use of human tissues in biochemical and cell based assays.Testing allograft integrity after treatment regimens applied to the tissues pre and post storage at ambient or low temperatures.Input into R&D lab management from health and safety to GLP/GMP related aspects, including maintenance of quality database, validation of equipment, temperature mapping, COSHH and risk assessment.Laboratory equipment maintenance and problem solving.Project management from conception to completion with reporting of results in meetings, peer reviewed journals and conferences.Previous experience of running functional pharmacology assays on human tissue such as cerebral and coronary arteries, bronchus, cardiac muscle, colonic smooth muscle and mucosa. Running projects for both internal and external clients.Specialties: Human tissue dissection and manipulationBiochemical and cell based assays.Histology.Low temperature storage of viable and non-viable allografts.Project managment.Problem solving.Development and Validation.Data handling and analysis.Writing for peer reviewed journals and presentations at conferences.Working towards and within a GLP/GMP environment.

Listed skills include Cell, R&D, Glp, Research, and 17 others.