Mark Wenlock Email & Phone Number

Nether Alderley, England, United Kingdom

Managing the business expansion and diversification of world-class Physical Chemistry services

Alderley Park, United Kingdom

Leading a high-performing and diverse team of 20+ scientists delivering world-class and timely Physical Chemistry data to a varied and expanding customer base.

Manchester, United Kingdom

InSilicoLynx focus is the development of software that provides Medicinal Chemistry access to in-vivo exposure parameter estimates at the drug design stage.

Understanding the impact of experimental and prediction errors on drug design decisions.Developed automated data preparation, transformation, modelling, and presentation processes.Supported neglected tropical disease (NTD) organisations. Specifically Liverpool School of Tropical Medicines and Medicines for Malaria Venture.Collaborated with the European.

Overhauled internal dose-to-man prediction application used within early drug discovery.Developed hybrid QSA(P)R models for more advanced, and expensive, ADME endpoints. Provided timely and high-quality in silico predictions for such endpoints. Drug discovery projects were able to use these with confidence. Reducing demand for experimental resources.Expert.

Applied knowledge in the following areas to support respiratory and inflammation drug projects: - Predictive sciences (QSAR, computational chemistry) - Physical organic chemistry - ADME - Drug designExpert knowledge in the determination of aqueous solubility, hydrophobicity, pKa, and plasma protein binding. Using state-of-the-art automated and LC/MS/MS.

Phd, Organic Chemistry

Photochromic Fluors

Bsc, First; Applied Chemistry