Mark Dell'Aringa Email & Phone Number

Durham, North Carolina, United States

• Leads a team of three in full validation of cell-based neutralizing antibody assay
• Writes validation plans, sample analysis plans, methods, and worksheets for GCP/GCLP and GLP studies
• Creates schedule for cell maintenance of three human cell lines used in six immunoassays
• Plans qualification and validation experiments for cell-based neutralizing antibody, pharmacokinetic, and toxicokinetic assays.
• Compiles data from in-study cut point, qualification, and validation experiments into summary tables in excel for presentation to client.
• Drafts reports for sample analysis, validation, and critical reagent bridging

Durham, North Carolina, United States

• Prepared and reviewed summary data tables, study binders, data packs, and assay and reagent preparation worksheets
• Sent summary data tables for bridging studies and method revisions to client for feedback and approval
• Led cell-based immunoassay work by updating method and method worksheets, tracking inventory, preparing new reagents, bridging controls, organizing study materials, and training new analysts
• Wrote training SOPs, data analysis templates, study reports, amendments, and addendums
• Collaborated with QC and QA to ensure accurate and timely review of data packs, study binders, and method revisions
• Ran cell-based neutralizing antibody and pharmacokinetic immunoassays on MSD-ECL sector imager and Synergy platforms for sample analysis and validation studies in accordance with GCP/GCLP regulations

Denver, Colorado

• Researched the role of specific epigenetic regulators in lymphocyte development and function
• Planned and performed in vitro and in vivo molecular biology and immunology experiments to drive four projects
• Generated and adapted protocols for ChIP-qPCR, ELISA, Western blotting, flow cytometry and other techniques
• Trained lab technicians in general lab practices, genotyping, ELISA, cell culture, and retroviral transduction
• Presented ongoing research at academic conferences, departmental seminars, and joint lab meetings

Greater Denver Area

Raleigh-Durham, North Carolina Area

• Conducted immunology research to identify the role of Notch signaling in T cells during type-2 immune responses
• Contributed to weekly lab meetings by presenting data, discussing scientific literature, and critiquing talks
• Collaborated with graduate students, post-doctorates, and faculty within and outside the Reinhardt Lab
• Trained new lab members in flow cytometry, ELISA, real-time PCR, mouse handling and husbandry, fluorescence and two-photon microscopy, mammalian cell culture, and general lab practices
• Maintained and organized the lab’s 300-cage mouse colony and digital database

Urbana-Champaign, Illinois Area

• Utilized computational tools for full genome assembly of methanogen organisms

Urbana-Champaign, Illinois Area

• Conducted microbiology research, data analysis, and literature review for senior thesis
• Collected methanogen specimens on weekend-long sampling trips

Doctor Of Philosophy - Phd, Immunology

Bachelor Of Science - Bs, Cell/Cellular And Molecular Biology