Mark Doring Email & Phone Number

New Jersey, United States

London, Gb

Titian's Mosaic software is the leading laboratory sample management software solution for life science laboratories. My consultant role here involves collaborative Project Management with Pharma and Biotech clients to customize the Titian suite of Mosaic software products to their individual sample management needs. This includes:• In-depth analysis and documentation of laboratory procedures to accurately capture client requirements• Initiating development projects as necessary to provide new or augmented functionality• Working with programming staff to follow through on system configuration• Using my laboratory experience to test the system to ensure that the configuration meets the needs of the client• End-user training• Coordination of deployment and UAT involving the laboratory staff and instrumentation • Final acceptance and hyper-care after the system is moved into Production

A professional services consulting company, ResultWorks specializes in transforming the business strategies of Life Sciences companies into successful technology and process harmonization initiatives.The work entailed performance of in-depth analysis of laboratory procedures and processes to accurately capture client efficiencies, pain points, gaps and new requirements. The reports generated were to enable the client (mostly Big Pharma) to make informed decisions on where they needed to focus their efforts, as well as to suggest the best solutions for meeting their requirements based on budgetary and technical data. Summary findings were presented to upper management using easy to understand tables, diagrams and animation tools.

PMI certified coursework in project management.

Rahway, New Jersey, Us

Lead identification and optimization support of medicinal chemistry and pre-clinical discovery efforts through application of lab automation and IT tools within a secondary screening group. Responsible for a group of automation and IT scientists to develop and validate liquid and materials handling procedures in support of dose-dependant compound testing. Assay validation performed in accordance with published NIH guidelines. • Informatic support included SQL updates and maintenance of a database that linked to a SharePoint TeamSite, and specification and development of custom software products for compound management operations. • Discovery and evaluation of new technologies (instruments, software tools) to increase data quality and integrity and reduce manual efforts. • Initiated and managed vendor negotiations to upgrade and maintain laboratory instrumentation, while saving Merck more than $60K through securing various discounts. • Coordinated presentations by vendor experts in promulgating the proper use of their technologies to drive results and manage expectations.

Kenilworth, New Jersey, Us

Held positions of increasing scientific and managerial responsibility that enabled me to contribute significantly to meeting or exceeding High Throughput Screening (HTS, uHTS) departmental goals. * Our screening goals increased yearly to culminate with the successful evaluation of approximately 2 million chemical entities through a battery of 20 – 30 novel biochemical and cellular assays each year* I played a key role in bringing in new technological improvements to transition screening from test tubes to 96 to 384 to 1536-well formats* I’ve evaluated talent since early in my career and built and managed teams of up to 13 FTE’s in support of biochemical and cell-based screening. I have used many methods and tools for personnel assessment, and have supervised temporary, part-time, contract and full-time employees• Liquid handling methods programmingTransition of assays from the bench to automated platforms by working closely with bench scientists, and developing specific reagent handling methods• Application of Project Management techniques to determine appropriate process and automation needs• Assay development and performanceCharacterization and execution of a wide variety of in vitro assays, statistical review of data and report generation• Compound management for various sample sets (Natural Products, CombiChem, Synthetics)Sample acquisition, storage, prep, and formatting. Method development for mixture creation(orthogonal, etc.), hit picking, and rearray to meet assay needs• IT development and supportProgramming (liquid handling, microplate processing, supervisory scheduling software, etc.)• Management of vendor interactions to specify systems, critically review products, instruct staff and resolve issues• Management of interactions with site facilities staffWorked as a department rep and key decision maker for a wide variety of facilities projects.Work with SPRI R&D engineering to design and build peripherals specific to our needs

Kenilworth, New Jersey, Us

Supervision of three BS level scientists in the development, optimization and performance of a wide variety of in vitro biochemical assays using radioisotopic and colorimetric tracers. Assay types included ELISA, enzyme inhibition, and receptor binding assays. Biochemical techniques included: determination of enzyme kinetics, characterization of receptor binding systems, enzyme and receptor isolation and preparation, protein purification through affinity chromatography, radioligand synthesis and purification, tissue culture of mammalian carcinoma cell lines, and small animal handling. Coordinated testing of unique structure compound files through all biochemical and microbiological assays running at the Bloomfield facility. Data analysis and reporting was handled using RS/1 software. Created custom software products for data analysis by programming using RPL.Developed automated liquid handling procedures (using Tecan robotics) for natural product sample preparation, and for biochemical assay performance. Developed various specialized protocols to facilitate labor-intensive assay steps: organic phase separation for a cholesterol transferase assay (ACAT), anion chromatography for the HIV reverse transcriptase, and homogeneous, temperature controlled cell suspension additions for phospholipase assays.Assisted in the design and integration of a gantry robotic system for the automation of sample preparation and sample transfer procedures. Provided all automated liquid handling code, and collaborated closely with Schering’s R&D engineering staff for fabrication and modification of various custom components.

Kenilworth, New Jersey, Us

Performance and troubleshooting of established HPLC separation procedures for the detection of antifungal agents (everninomycin and ketoconazole). Development of solid phase extraction techniques for serum samples. Independent design of in vitro experimental protocols by adapting techniques obtained from the existing literature (myosin light chain kinase, phosphodiesterase type I). In addition, I performed quality control (RIA) on α-interferon samples, and biochemical screening of fermentation products and plant extracts for possible cell wall (chitin, glucan) synthetase inhibitors.

Geneva, Geneva, Ch

AA, GC, and UV/VIS spectroscopic analysis of agricultural and petroleum products performed as a service to outside clientele. Quality control services following ASTM procedures included:• Wet chemical analysis of reagents, petrochemicals and petroleum distillates.• Gasoline octane rating and residual fuel oil analysis.• Moisture and fat content determinations of agricultural products.• Recommendation of cargo acceptance according to industrial specifications.Assignments also included performance of job responsibilities on second shift, and 24-hour on-call service on an alternating schedule.

Master Of Science (Ms), Biology

Bachelor Of Science (Bs), Biochemistry

Education record