Phd Candidate - Molenaar Lab (Prinses Máxima Centrum Voor Kinderoncologie)
CurrentThis PhD project aims at finding drug sensitivities for neuroblastoma by combining data of neuroblastoma tumors and in vitro models. Furthermore, this project aims to create new in vitro models to study neuroblastoma in more detail. In a new project within the ITCC-P4 partner consortium, we will compare tumoroids and patient-derived xenografts (PDX) as model systems and aim to build a connected repository for both in vitro and in vivo studies. We will examine correlations of drug sensitivities with specific neuroblastoma subtypes, different target expression levels or genomic aberrations.