Daniel Martel, Phd Email & Phone Number

Île-De-France, France

Île-De-France, France

Assigned to multiple roles and responsibilities: • R&D project management: development of new real-time PCR tests for the diagnosis of infectious diseases.• Quality Management: application, updating and management of the QMS (ISO 13485 certified system).• Manufacturing: production of CE-marked PCR kits.• Regulatory affairs: working towards IVD compliance with Regulation 2017/746 (IVDR).• Scientific support to customers.About the company: BIO-EVOLUTION is a French IVD manufacturer owned by EUROIMMUN France, a subsidiary of the EUROIMMUN Group, a Revvity company.

Paris, France

• Investigated the role of an essential protein kinase of the Leishmania parasite in parasite biology and host cell subversion.• Adapted a pre-existing CRISPR-Cas9 toolkit to a field-relevant Leishmania species and shared the technique with several laboratories in Europe and endemic areas within the international network of the Institut Pasteur. --> This method has increased the speed of Leishmania genome editing by more than 12-fold, dramatically accelerating discoveries about this deadly disease.• Wrote and participated in the submission process of 3 articles as first author, resulting in one being published and two others to be published soon.• Presented and discussed my research at 6 international conferences.• Trained new team members in sophisticated microscopy methods and molecular or biochemical techniques.• Supervised masters and undergraduate students.• Demonstrated a strong ability to adapt to change and take on challenges to achieve set goals, with excellent problem solving skills and self-discipline.Supervisor: Dr Najma RachidiLab: Dr Gerald Spaeth's Molecular Parasitology and Signalisation unit @ Institut Pasteur (Paris, France)

Paris, France

• Awarded a 3-year LabEx IBEID PhD Fellowship for promising preliminary results on a Leishmania protein kinase.

Paris, France

• Investigation of the immune evasion strategies of two parasites responsible for Chagas disease and animal sleeping sickness.• Development of parasitic cell lines expressing double fusion proteins with a bioluminescent and fluorescent marker to track parasite infection in a mouse model using an in vivo imaging system.Lab: Dr Paola Minoprio's Trypanosomatids Infectious Processes unit

Paris Area, France

• Investigated the possibility of adding a nanofiltration step to an existing process for the purification of a plasma protein.• Conducted pilot-scale experiments of fluidised bed chromatography for the high-efficiency purification of an immunoglobulin.• Ensured that all laboratory equipment was properly maintained and that safety and SOPs were followed.

Paris Area, France

• Optimised an existing chromatography method to purify the inter-alpha-trypsin inhibitor (ITI) protein from human plasma, which could be developed for the treatment of sepsis.

Liège, Belgium

• Development of a high throughput screening and production of engineered enzymes to study protein-protein domain interactions in a CMO/CRO biotechnology company.

Doctor Of Philosophy (Phd), Infectious Diseases

Activities and Societies: PhD students representative in the Parasites and Insect Vectors Department at the Pasteur Institute (2017-2019).

Master'S Degree, Infectious Diseases - Microbiology, Virology, Immunology

Master 2: Infectious Diseases - Fundamental Microbiology (with Microbiology course at Institut Pasteur) Master 1: Infectious Diseases.

Bachelor'S Degree In Biotechnologies, Cellular And Molecular Biology

Associate'S Degree, Biological Engineering - Food Industries And Biology