I am an excited protein scientist who wishes to understand how diverse chemical reactions are catalysed by macromolecular catalysts (enzymes) evolved in living creatures. To this end, I combine molecular biology, biochemistry, and structural biology (X-ray crystallography and cryo-electron microscopy) to obtain atomic-level molecular insights into the three-dimensional structure, function, and regulation of enzymes. I also develop protein engineering strategies and chemical tools that selectively modulate molecular functions of enzymes; exploitable in basic research as well as in environmentally friendly cutting-edge biotechnologies. The long-term goal of my research is to address an unanswered fundamental question: how do enzymes acquire the structural diversity and conformational flexibility that allow them to evolve towards new molecular function?