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Martin Tolar, MD, PhD, Founder, President & CEO at Alzheon, Inc., Founder & Director at Tolion Health, Inc.Prior to founding Alzheon in 2013, Dr. Tolar has held executive positions in life sciences companies, where he has successfully established and grown new companies, business areas and product opportunities. Dr. Tolar served as President & CEO of Knome, Inc., where he pioneered human genome interpretation systems and services, as President & CEO at NormOxys, Inc., where he built and financed the business for novel cancer therapeutics, and as CSO and CBO at CoMentis, Inc., where he developed the first clinical beta secretase inhibitor platform and negotiated a landmark deal for the program for $1.1 billion with Astellas Pharma in 2008. Dr. Tolar held clinical development and business leadership positions at Pfizer, where he was instrumental in a wide range of business transactions, including acquisition of Rinat Neuroscience for $500 million in 2006, and directed programs through all stages of clinical development.During his academic career, Dr. Tolar served as an Assistant Professor in the Department of Neurology at Yale University School of Medicine, where he focused on movement disorders. Dr. Tolar trained in Neurology at the Boston Medical Center, received a Ph.D. in Neuroscience for his work on the role of apolipoprotein E in Alzheimer’s disease, and published many scientific publications in the area of neuroscience and neurodegenerative disorders. Dr. Tolar received his M.D. from Charles University in Prague, where, as a medical student, he helped organize and lead the Velvet Revolution that toppled the communist regime in the former Czechoslovakia in November 1989.In 2021, Dr. Tolar founded the International Neurodegenerative Disorders Research Center, INDRC, a global institute applying artificial intelligence and machine learning solutions to identify therapeutic interventions for Alzheimer’s disease and other neurodegenerative disorders. He served as the Chairman of the INDRC Executive Board through 2024. Dr. Tolar also serves on business and scientific boards including the Alzheimer’s Drug Discovery Foundation, the Alzheimer Foundation and Advance Healthcare Management Institute.Dr. Tolar was recognized as one of the Top 100 Most Influential People in the world of drug development and manufacture by The Medicine Maker Magazine’s Power Lists for 2016, 2017, 2018 and 2019. In 2021, Dr. Tolar received the Czech Laurels Award from the Czech Chamber of Commerce in recognition of his leadership in Alzheimer disease therapeutics.
Tolion Health, Inc.
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Founder & DirectorTolion Health, Inc. 2023 - PresentTolion Health, Inc. provides preventive, predictive and personalized brain health and longevity guidance based on science and enabled by AI.We utilize novel AI technology to help people at increased risk of dementia maintain brain health and top performance, prevent disability and onset of symptoms by providing personalized life-long preventive and predictive health and longevity guidance.Our goal is to improve brain health and longevity through targeted interventions and personalized recommendations towards better health management to lengthen and improve quality of life using measurable achievements that incorporate evolving personal goals and needs.
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Founder, President & CeoAlzheon, Inc. 2013 - PresentFramingham, Ma, UsAlzheon, Inc. is a clinical-stage biopharmaceutical company developing a broad portfolio of product candidates and diagnostic assays for patients suffering from Alzheimer’s disease and other neurodegenerative disorders. We are committed to developing innovative medicines by directly addressing the underlying pathology of neurodegeneration.Our lead Alzheimer’s clinical candidate, ALZ-801 (valiltramiprosate), is an oral agent in Phase 3 development as a potentially disease modifying treatment for AD. ALZ-801 is an oral small molecule that fully blocks formation of neurotoxic soluble amyloid oligomers in the brain.Our clinical expertise and technology platform are focused on developing drug candidates and diagnostic assays using a precision medicine approach based on individual genetic and biomarker information to advance therapies with the greatest impact for patients. -
Business Advisory Board & Scientific Review BoardAlzheimer'S Drug Discovery Foundation 2013 - PresentNew York, Ny, UsThe Alzheimer’s Drug Discovery Foundation is non-profit organization whose mission is to accelerate the discovery and development of drugs to prevent, treat and cure Alzheimer’s disease, related dementias and cognitive aging. The Foundation raises and awards funds to academic and biotechnology scientists conducting drug discovery research in this field, using a venture philanthropy model to bridge the worldwide funding gap between basic research and later-stage drug development, using any return on investment to support new research. -
Scientific BoardThe Alzheimer Foundation 2011 - PresentThe Alzheimer Foundation supports research of Alzheimer disease and other neurodegenerative and brain vascular diseases that lead to cognitive malfunctions and dementia, and strives to improve quality of patient care, extend the framework of care offered, and improve conditions under which it is provided. Foundation enables: a) expansion of diagnostic, medical and therapeutic methods; b) cooperation and support among scientists, medical doctors and other health care professional in the Czech Republic and abroad; c) scientific research and education of medical doctors and staff in patient care and treatment.
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Academic BoardAdvance Healthcare Management Institute 2009 - PresentPraha 4, Praha, CzAdvance Healthcare Management Institute strives to improve the management of health care in the Czech Republic, especially at the management level of organizations, with focus on rational decision-making based on facts and needs of patients and insured, thereby increasing both quality and efficiency of health services. Institute's mission is to provide exceptional educational programs focused on the practical needs of healthcare managers and supply them with the experience of the best run organizations in the Czech Republic and abroad by establishing strategic partnerships with renowned educational institutions. -
Founder, Chairman Of Executive BoardIndrc - International Neurodegenerative Disorders Research Center Sep 2021 - Sep 2024Praha 6, Prague, CzThe INDRC, International Neurodegenerative Disorders Research Center, is a private, non-profit, global research institute based in Prague, Czech Republic, that for the first time combines biological sciences and medicine with big data and artificial intelligence approaches to study and treat Alzheimer’s disease and other neurodegenerative disorders.The INDRC goal is to merge and advance the globally dispersed knowledge in brain systems and neurodegeneration through research training fellowship programs of excellence, delivering outstanding independent research programs, building a world-class research community, and enabling technological and therapeutic innovations with genuine impact on society and humanity. INDRC is interdisciplinary by design, addressing research bottlenecks and developing new analytical approaches to discover and model the non-linear dynamics between biology, disease, man, and environment. The Institute uses a transparent governance model that includes committed international partners from European Union, North America and around the world, including universities, research institutes, clinical centers, and for-profit/non-profit companies. INDRC projects apply artificial intelligence and machine learning to address the challenges facing the identification and validation of new therapeutic interventions in Alzheimer´s and other neurodegenerative disorders to advance therapies with the greatest impact for patients. -
Board Of DirectorsBellus Health 2010 - 2017Laval, Quebec, CaBellus Health is a public development-focused healthcare company concentrating on products that provide innovative health solutions and address critical unmet medical needs. Bellus Health is based in Laval, Quebec and its shares trade under the ticker BLU on the Toronto Stock Exchange. -
President & CeoKnome, Inc. 2011 - 2013Cambridge, Ma, UsKnome is a leading provider of human genome interpretation systems and services, helping academic, pharmaceutical and clinical clients in two dozen countries identify the genetic basis of disease, tumor growth, drug response and treatment. Company’s big data technologies accelerate and industrialize the process of interpreting whole human genomes, facilitating the healthcare industry’s transition to molecular-based, precision medicine. Knome is headquartered in Cambridge, Massachusetts, with IT facilities in Hyderabad, India. -
Board Of DirectorsSuven Life Sciences Ltd. 2007 - 2013Hyderabad, Telangana, InSuven is a public biopharmaceutical company focused on innovative drug development and commercialization of novel first-in-class or best-in-class therapies for neuropsychiatric, inflammatory and metabolic disorders through the use of GPCR targets. The company is a leading provider of full spectrum services in drug discovery, development and manufacturing under collaboration with global life science companies. -
President & CeoNormoxys Inc. 2009 - 2011UsNormOxys is a private biotechnology company founded by Nobel Laureate Jean-Marie Lehn. NormOxys is developing a novel class of small molecule drugs, oxyrens, which enhance the body’s ability to deliver oxygen more efficiently to hypoxic diseased tissues, such as may be present in cancer, cardiovascular diseases, anemia, Alzheimer's disease, stroke and diabetic retinopathy. -
Executive Vice President & Chief Business OfficerComentis, Inc. 2008 - 2009South San Francisco, Ca, UsCoMentis is a private biotechnology company engaged in the discovery and development of small molecule drugs to treat Alzheimer's disease, age-related macular degeneration and cognitive disorders utilizing two versatile technology platforms: (i) aspartic protease inhibitors for Alzheimer's disease and infectious disorders; and (ii) nicotinic acetylcholine receptor agonists and antagonists for the treatment of angiogenesis-mediated diseases, as well as cognitive and inflammatory disorders. -
Chief Scientific OfficerComentis, Inc. 2007 - 2008South San Francisco, Ca, Us
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Worldwide Business DevelopmentPfizer 2005 - 2007New York, New York, Us -
Neuroscience Clinical DevelopmentPfizer 2001 - 2005New York, New York, Us
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Assistant ProfessorYale University School Of Medicine 2002 - 2007New Haven, Ct, Us
Martin Tolar, Md, Phd Skills
Martin Tolar, Md, Phd Education Details
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University Of Michigan - Stephen M. Ross School Of BusinessExecutive Management -
Boston Medical CenterResidency In Neurology
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University Of Cincinnati College Of MedicineNeuroscience
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Charles UniversityMedicine
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Czech Technical University In PragueComputer Science
Frequently Asked Questions about Martin Tolar, Md, Phd
What company does Martin Tolar, Md, Phd work for?
Martin Tolar, Md, Phd works for Tolion Health, Inc.
What is Martin Tolar, Md, Phd's role at the current company?
Martin Tolar, Md, Phd's current role is Founder, President & CEO at Alzheon, Inc. | Founder & Director at Tolion Health, Inc. | Founder at INDRC | Alzheimer’s Disease Research.
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What schools did Martin Tolar, Md, Phd attend?
Martin Tolar, Md, Phd attended University Of Michigan - Stephen M. Ross School Of Business, Boston Medical Center, University Of Cincinnati College Of Medicine, Charles University, Czech Technical University In Prague.
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Martin Tolar, Md, Phd has skills like Sales Management, Business Strategy, Solution Selling, Key Account Management, Product Marketing, Marketing Strategy, Cloud Computing, Business Development, Sales Operations, New Business Development, Go To Market Strategy, Channel.
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