Mathen Kumar Email & Phone Number

Ooty, Tamil Nadu, India

Planning and execution of Breeding scheduled as per the organisation requirment.Scheduling change of bedding, cage and water bottle in routine basis.Monitoring and recording of humidity, tempertature, pest control in breeding, quarantine, procedure, acclimatization, post mortem and storage rooms.Conducting health monitoring programme periodically for mice, guinea pigs and rabbits.Follow quarantine procedures for external animals purchased from approved vendor.Stock… Show more Planning and execution of Breeding scheduled as per the organisation requirment.Scheduling change of bedding, cage and water bottle in routine basis.Monitoring and recording of humidity, tempertature, pest control in breeding, quarantine, procedure, acclimatization, post mortem and storage rooms.Conducting health monitoring programme periodically for mice, guinea pigs and rabbits.Follow quarantine procedures for external animals purchased from approved vendor.Stock maintanence of animal, feed and bedding materials.Procurement of materials and animals from approved vendors.Monitoring micro and macro environment of the animal house facility.Ensure the sterilization of animal cages, water bottles and bedding materials routinelySending feed and test sample for analysis for third party testing.Selection of animals for test procedures by weight, gender and age.Perform preclinical test for rabies vaccine as per protocol.(Potency test, LD50 test, Abnormal Toxicity test, Intracerebral test for absence of Living virus as per I.P and B.P) for regular, stablity batches.Perform analytical method validation and stability studies as per ICH guidelines.Preparation of Challenge Virus standard bank for potency assay.Coordinate with validation team for equipment calibration.Write log sheets and raw data sheets for each experiments for batch submission.Prepare SOP's, STP's, TRENDS, Summary report, revalidation report, reverification and establishment oreport for assays and Standards.Handle Quality Management System (QMS) works like Change control, deviation and CAPA.Proper updation of FORM B, FORM C & FORM D for related experimentation protocol.As incharge - Animal house facility (GLP CERTIFIED), prepare consolidated documents related to CPCSEA and IBSC minutes of meetings, Customer and Regulatory Audits (CDCSO and CDL).Monitoring of disposal of Biomedical waste management programme.Perform GLP training to qualify the analyst. Show less

Chennai Area, India

Working for the production of parental solution of Anti snake Venom Serum against Big Four snakes of India.Planning and execution of immunization and bleeding program in horses for manufacturing anti snake venom serum for therapeutic use (Parental solution - Sterile liquid).Ensuring sterile preparations of materials and reagents.Maintenance of records, registers regarding animal health, hematological, biochemical parameters details to ensure fitness of animals for biological… Show more Working for the production of parental solution of Anti snake Venom Serum against Big Four snakes of India.Planning and execution of immunization and bleeding program in horses for manufacturing anti snake venom serum for therapeutic use (Parental solution - Sterile liquid).Ensuring sterile preparations of materials and reagents.Maintenance of records, registers regarding animal health, hematological, biochemical parameters details to ensure fitness of animals for biological production of antiserum against snake toxins.Procurement of snake toxins and estimates its lethal dose level in vivo.PCollection of blood from sheep and horses guided by veterinarian.Perform Median lethal dose test, neutralization test for snake toxins against its antibodies to estimate effective dose (Potency)Monitoring and recording horse blood collection, plasma separation and preservation.Ensuring all utilities and reagent requirement for plasma processingConvert plasma lots to therapeutic biomolecules through digestion, concentration and maturation of antiserum.Estimation of protein, phenol, caprilic acid and pH as per the Indian pharmacopeia in snake venom antiserum.Sterile filtration and filling (primary packing) of manufactured batches.Batch coding, label coding of batches.Writing Batch Manufacturing Record, Batch Packing Record, process records.Prepare SOP's, STP’s, and Trends.Coordinating validation of lab equipment’s by third party agents. Show less