Mathilde Couteaudier Email & Phone Number

Marigné-Laillé, Pays De La Loire, Fr

Tours, Centre-Val De Loire, France

In the U1259-MAVIVH team headed by Philippe Roingeard and under the supervision of Philippe CHOUTEAUStudy of the role of hypoxia-inducible factors (HIFs) on the assembly and morphogenesis of hepatitis C virus (HCV) in differentiated cells in prolonged hypoxia

Paris, Ile-De-France, France

In the Insect-Virus interactions unit headed by Dr Louis LAMBRECHTS.Topic: Study of the mechanisms used by flaviviruses against the antiviral response in mosquitoes. Study of antiviral immunity by RNA interference in the Aedes aegypti mosquito against the Dengue virus. Role of sfRNA (subgenomic flavivirus RNA) in the transmission of flaviviruses to humans by mosquitoes (Zika and West Nile viruses).

Paris Area, France

In the Epidemiology and Physiopathology of Oncogenic Viruses unit headed by Antoine Gessain and under the supervision of Florence BuseyneTopic: Human infection with zoonotic simian foamy viruses: role of virological and immunological factors in the restriction of viral emergence (ANR-REEMFOAMY project)Characterization of neutralizing antibodies against foamy retroviruses in humans. Mapping of neutralizing epitopes using chimeric foamy viral vectors. Study of viral cell-to-cell transmission mediated by the envelope glycoprotein. Role of neutralizing antibodies in such a transmission.

Tours Area, France

PhD Director : Jean-François Vautherot - PhD Co-Director : Caroline DenesvreTopic: Replication, dissemination and morphogenesis of Marek’s Disease Virus in differentiated cells of the dermo-epidermal lineage (ANR MADISPREAD project - EMIDA Era-Net) – (PhD obtained on October 19th 2015).Development of two new cell systems, one based on the differentiation of chicken embryonic stem cells into keratinocytes and the other one based on the organotypic culture of chicken embryonic skin at the air/liquid interface, in order to study Marek’s Disease Virus replication and morphogenesis.

Advisor: Dr. Noël Tordo (Pasteur Institute Paris) - Co-Advisors : Dr Philippe Marianneau (ANSES Lyon), Dr Frank Sauvage (Lyon I University)AFSSET Research project: Dynamics of Puumala virus in bank voles from endemic and non endemic regions for Hemorrhagic Fever with Renal Syndrome (HFRS) in France.Characterization of the circulation of hantaviruses in France: Health and environmental risks.Development of detection tests for hantaviruses in bank voles with traditional molecular methods and sequencing. Development of technics of viral culture and viral isolation.

Evaluation and Optimization of two cell systems for vaccinal virus productionVirology and vaccinology, Developement of cell culture systems in bioreactor.

Phd - Doctor Of Virology And Cell Biology, Virology And Cell Biology, Doctor Phd

Activities and Societies: INRA - ISP - Nouzilly - Tours Animal testing diploma of the university of Tours - Level 1 Animal testing diploma.

Biotechnology Engineer, Biotechnology

Activities and Societies: Member of student association

Education record