Matt Applegate Email & Phone Number

Gainesville, GA, US

Auckland, New Zealand, NZ

-Oversee site P&L of ~$25m-Achieved inventory reduction of more than 50% YOY 2023 vs 2024-Achieved revenue growth of almost 40% YOY 2023 vs 2024-Oversee site staff with ~100 direct and 10 indirect staff-Oversaw staff growth of 20% YOY 2023 vs 2024-Responsible for all manufacturing attainment in the US-Responsible for supporting all business development.

-Active member of the Medgene Labs executive leadership and management team-Responsible for 7 departments and 26 FTEs: Viral and Bacterial Manufacturing, Fill and Finish, Process Development, Warehouse and Logistics, Quality Control, Facilities and Maintenance-Leading all manufacturing efforts for the company-Provides strategic oversight and direction to.

Burlingame, CA, US

Burlingame, CA, US

-Collaborate with commercial management teams to establish strategic commercialization plans.-Establish strategic site master plan.-Lead transition of site into an operational commercial manufacturing facility.-Drive process improvements to decrease manufacturing costs.-Perform detail cost analysis of manufacturing operations using process modeling.-Lead.

Burlingame, CA, US

Establish and direct all manufacturing site operations for the Elwood, KS manufacturing site. Manufacturing operations to include biologic and pharmaceutical manufacturing under regulation by USDA, FDA, and EMA.-Design and renovate manufacturing facility to enable large scale GMP manufacturing capabilities. -Design and renovate facility into state of the.

Blue Bell, PA, US

Lead Process Engineering for the Midwest region. Lead a group of 4 global oriented process engineers.Lead Process Engineering for facility expansions and modifications for companies in the animal health vaccine production facilities, animal health pharmaceutical production, food flavoring manufacturing, and microbiological testing.Projects encompassed.

Waltham, MA, US

Led multiple teams across operations, including two Product Performance laboratories, Process Control, Media and Process Development, Operations HSE, Blood Supply Chain and site Research and Development (7 departments with 52 FTE’s). Worked on internal and external product transfers, production lab design and build, new ISO 11133 adaptation/certification.

Libourne, FR

-directed operations for 10 production departments across two sites. Included Live and Inactivated Batching, Inactivated Filling, Live Filling/Lyophilization, Bacterial Antigen Production, Custom Vaccine Production, Tissue Culture Antigen Production, Chicken Embryo Antigen Production, Egg Pre-Incubation, CAV and Diluent Production. Consisted of 7.

Libourne, FR

-managed 6 departments (Live and Inactivated Batching, Inactivated Filling, Live Filling/Lyophilization, Bacterial Antigen Production, Custom Vaccine Production, and Tissue Culture Antigen Production) consisting of 6 Supervisors and 30 technicians-managing daily activities for all reporting production departments-reviewing and approving all formulations.

Libourne, FR

-managed 4 departments consisting of 4 Supervisors and 20 technicians-managed daily activities for all reporting production departments-reviewed all formulation templates to ensure accuracy-reviewed and approved all formulations for live and inactivated semi-finished goods-assisted in establishment of SIP processes throughout the site-lead the transition.

Libourne, FR

-managed 2 departments consisting of 2 Supervisors and 10 technicians-managed daily activities for standard licensed and custom bacterial antigen production-lead the project for design, development, installation, operation, validation, and process qualification of a bleed and feed tangential flow filtration skid to concentrate live bacterial.

Leverkusen, North Rhine-Westphalia, DE

In addition to previous duties:-performed human resource management responsibilities-maintained all production deviation events for HA production-organized all calibration and maintenance activities within the production schedule-performed product releases for raw materials-performed duties as assigned by the production manager-organized and supported all.

Leverkusen, North Rhine-Westphalia, DE

In addition to previous responsibilities: -supervised a team of four production technicians-coordinated production plant shutdowns-involved in hiring of new production technicians-created and maintained the area production schedule based on forecasted product needs-created and maintained sampling schedule with Quality Control-maintained inventory of.

Leverkusen, North Rhine-Westphalia, DE

In addition to previous responsibilities:-assisted in the development of an operator certification/development program-maintained batch production records and complete review of finished production records on a timely basis-assisted in the development and review of validation protocols-took part in the multi-week Bayer International Management Simulation.

Leverkusen, North Rhine-Westphalia, DE

In addition to previous responsibilities:-revised Batch Production Records and SOPs-reviewed batch production records and SOPs-trained coworkers-involved in process and equipment risk analysis-actively involved in installation qualification and operational qualification of numerous pieces of equipment including stainless steel fermentors, Carr P18.

Zurich, Zurich, CH

-Hyaluronic Acid production (consisted of multi-pass fermentation, flow through continuous pass centrifugation, cell removal microfiltration, bleed and feed plate and frame ultrafiltration, concentration, and diafiltration, clarifying filtration, sterile filtration, alkaline hydrolysis, and ethanol precipitation)-demonstrated a working knowledge of.

Emporia, KS, US

-prepared culture media-monitored and stored food product samples-maintained stock cultures for Microbiology and Pathogenic Microbiology Laboratory classes-performed ELISA and DNAH assays-monitored and maintained a mouse virulence study-observed and documented organism occurrence-performed statistical analysis of study data

Master'S Of Sciences, Microbiology

Bachelors Of Sciences, Microbiology