Matt Barrows, Mba Email & Phone Number

Duxbury, MA, US

Consulting services for Biotech and Pharmaceutical companies. Specializing in CMC, Manufacturing, Tech Transfer, Operational Excellence

Cambridge, Massachusetts, US

Cambridge, Massachusetts, US

Responsible for Large Scale Clinical and Personalized Cancer Vaccine manufacturing at Moderna's Norwood, MA facility. Including production of Moderna's coronavirus vaccine candidate

Cambridge, Massachusetts, US

• Leading Manufacturing team for 1st COVID-19 (corona virus) Vaccine as of early February 2020. Led the design and rapid startup of Moderna’s PVC operation at its innovative drug manufacturing facility in Norwood. As.
• Oversee design and build phases & run and maintain operations with a team of 30 quality and operations staff. Hired and trained all management and staff.
• Established operational excellence team: hiring and onboarding talent, setting targets, and developing KPIs.
• Built portfolio of Continuous Performance Improvement projects (CPI) & master Continuous Improvement Plan (CIP).
• Initiate Lean Value-stream mapping initiative – implementing material and information-flow mapping & new SOPs.
• Analyzed and revamped operational quality systems into alignment with cGMP guidelines and best-in-class ideals.

Boston, Massachusetts, US

• Head of Operational Readiness - Smithfield, RI March 2017 – July 2017Head of Alexion’s Operational Readiness Program for a major capital project with new capacity buildouts. Built and oversaw a cross-functional team.
• Scope: Manufacturing, Clean Utilities, Warehouse & Distribution, Validation post-commissioning & qualification.
• Collaborated with and provided executive leadership to Construction Project and Operational Project direct reports.Associate Director Commercial Upstream Operations Dec 2014 – March 2017Headed Alexion’s Commercial Cell.
• Optimized and ran a portfolio of 30 process improvement projects.
• Manufacturing Lead for capital expansion project.
• Member of the Site Safety Leadership Team for new buildout.

Paris, France, FR

• Associate Director Bulk Manufacturing Consent Decree March 2011 – Dec 2014Head of Bulk Manufacturing Consent Decree remediation teams. Full accountability for implementing the consent decree (CD) workplan for the.
• Applied Lean principles & ‘Systems Thinking’ to achieve Upstream and Downstream operational excellence for a rare disease product.
• Managed team of 4 Senior Managers, 10 Manufacturing Specialists, and 2 Quality Engineers.
• Prepared and delivered mission-critical presentations to senior leadership and to Third-Party Quality oversight teams.
• Successfully completed CD while re-establishing Production Controls Quality System

Paris, France, FR

• Manage a team of supervisors, MFG specialists and 20+ operators across 2 shifts 7 days a week overseeing the protein purification of Myozyme, Cerezyme and Fabrazyme. Responsibilities include adherence to a demanding.
• Worked directly with the Global Operation Excellence Group implementing Lean concepts to the manufacturing floor.
• Represented Protein Purification for multiple regulatory audits including FDA and European Medicines Agency (EMA).
• Responded to inquiries from regulatory agencies; developed and implemented responses to audit observations.

Paris, France, FR

• Supervise Process Engineers in the Automation Engineering department at Allston Landing. Duties include, managing and scheduling process improvements project work while maintaining around the clock automation support.
• Kept team cool and calm, and ran interference when undue pressures hit.
• Maintained around-the-clock automation support for Delta V and PLC systems for Cell Culture, Protein Purification, and Support Services.
• Functional role—Manager, Automation Engineering: Supervised 6 Process Engineers.

Paris, France, FR

• Automation Engineering Manager—Managed the development of Automation Software for Genzyme Belgium plant
• Coordinated transdisciplinary effort in Genzyme US; Genzyme Flanders; and Engineering firms in the U.S. and Ireland.
• Developed functional requirements specifications; and process model diagrams; and mapping of the brand-new facility.
• Engaged US & Flanders staff in achieving aggressive KPI metric targets.
• Learned Automation at rapid-fire speed. | Obtained crash-course in PMP project management.

Paris, France, FR

Executed validation protocols & managed Automation Specification documentation for Automation Engineering. Performed and led the validation effort, executing OQ protocols for newly developed automation software for Geel expansion. Partnered with Jacobs Engineering and Genzyme Belgium for Functional Requirements. Delta V and PLC software developmebt

Paris, France, FR

Performed multi-stage, large-scale column chromatography & microfiltration operations according to cGMP Guidelines.

Master Of Business Administration - Mba

Bs, Biotechnology