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Experienced drug development professional with over 15 years dedicated to cardiovascular and diabetes research in the pharmaceutical industry. Throughout my bench scientist career, I honed my expertise in assay development, target validation, and pre-clinical drug development. In my current role as a project manager, I excel in collaborating with cross-functional teams to develop and execute project strategies while fostering effective communication and teamwork.My extensive background in cardiovascular drug development encompasses various pillars, including heart failure, Atrial fibrillation, anti-obesity, diabetes, and more. With a deep understanding of these therapeutic areas, I have consistently contributed to the advancement of innovative treatments and therapies.My commitment to research excellence extends beyond technical expertise. I am passionate about building and maintaining effective teams and employing a collaborative approach to problem-solving. By integrating diverse perspectives and leveraging collective strengths, I have successfully delivered on project objectives and exceeded organizational goals.
Novartis Institutes For Biomedical Research (Nibr)
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Global Project ManagerNovartis Institutes For Biomedical Research (Nibr) Feb 2023 - PresentCambridge, Massachusetts, United StatesI have successfully led and managed diverse cardiovascular projects throughout their lifecycle - from early discovery to IND approval and into the clinic. My expertise lies in effectively collaborating with cross-functional teams, developing and executing program strategies, and fostering effective communication and teamwork, all with a unified goal in mind. -
Senior Scientist IiNovartis Institutes For Biomedical Research (Nibr) Jun 2020 - Apr 2023Cambridge, Massachusetts, United States -
Scientist IiNovartis Institutes For Biomedical Research (Nibr) Apr 2018 - Jun 2020Cambridge, Massachusetts -
Scientist INovartis Institutes For Biomedical Research Mar 2013 - Apr 2018Cambridge, Massachusetts -
Research Associate IiNovartis Institutes For Biomedical Research (Nibr) Dec 2008 - Mar 2013Cambridge MassachusettsImbedded within analytical biochemistry group of CVM, my efforts were focused on supporting target/drug discovery for therapeutics aimed at treating cardiovascular disorders/diabetes. My specializations were lipid profiling, Immunoassays and assay development. Pioneered new methods including custom ELISAs, automation and robotics.I was also a member of the trials of the future initiative (TotF) which was a team tasked with evaluating and integrating point-of-care devices (POC) into clinical trials. -
Senior Technical Research AssistantHarvard Medical School 2007 - 2008Boston, MaWorking in the Bonventre Lab, I helped develop/optimize novel kidney injury analytes (ie. KIM-1) and/or integrate them with ELISA-variant assays. I routinely quantified/analyzed both pre-clinical and clinical samples in support of major studies and publications.I also routinely ran concentration/purification assays to collect and later concentrate unique antibody clones which were later used in ELISA-variant assays (ie. Luminex) -
Research Associate IiBrigham And Women'S Hospital 2007 - 2008Boston, MaWorking in the Vaidya lab, I helped drive many efforts. I developed/evaluated a POC renal diagnostic device by coupling novel kidney injury antibodies (KIM-1 and/or Cystatin C) with gold nano-particles.Evaluated various kidney function tests (BUN, sCr, Kim-1, Cystatin C, NGAL....others) to support publications.Directed in vivo dosing, organ harvesting and blood collection as part of an evaluation of the KIM-2 KO profile. Performed regular tissue collection and homogenization for IHC, RT-PCR and western blots.Publications:RenaStick: A Rapid Urine Test for Early Detection of Kidney Injury. Kidney Int. 2009;76(1):108-114.Comparative analysis of novel noninvasive renal biomarkers and metabonomic changes in a rat model of gentamicin nephrotoxicity. Toxicol Sci. 2009;109(2):336-349.TIM2 gene deletion results in susceptibility to cisplatin induced kidney toxicity. Tox Sci. 2010:118(1):298-306. -
Research AssistantThermo Fisher Scientific (Pierce Biotechnology) 2005 - 2007Woburn, MaDeveloped and validated assays for an ELISA-variant multiplexed chemiluminescence system. During my time in the research and development department, I validated over 10 analytes and developed 3 multiplexed panels.
Matt Clement Skills
Matt Clement Education Details
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Pharmacology - Drug Discovery & Development -
Biotechnology: Life Sciences -
Biology, Chemistry
Frequently Asked Questions about Matt Clement
What company does Matt Clement work for?
Matt Clement works for Novartis Institutes For Biomedical Research (Nibr)
What is Matt Clement's role at the current company?
Matt Clement's current role is Global Project Manager at Novartis Institutes for BioMedical Research (NIBR).
What is Matt Clement's email address?
Matt Clement's email address is ma****@****hoo.com
What schools did Matt Clement attend?
Matt Clement attended Harvard Medical School, Harvard University, Gardner-Webb University.
What are some of Matt Clement's interests?
Matt Clement has interest in Snowboarding, Soccer, Surfing And Jeeping.
What skills is Matt Clement known for?
Matt Clement has skills like Assay Development, Biochemistry, In Vivo, Immunohistochemistry, Elisa, Immunoassays, Molecular Biology, Cell Culture, Rt Pcr, Life Sciences, Antibodies, Biomarkers.
Who are Matt Clement's colleagues?
Matt Clement's colleagues are Ajay Tiwari, Ahreum Noh, Nadine Mihan Msn Rn Mscn, Katherine Lander, Brian Brandenburger, Fabio Grillo, Abanoub Samy.
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