Led a growing, diverse team of computational biologists and software engineers on federal projects at the leading edge of research methodology and technical practice. Responsible for technology development, domestication, and support to make Linux HPC and cloud services eminently accessible to novice and expert customers alike. Drove center-wide adoption of and integration with public and private cloud computing. Principal investigator or leadership role on over $170M in federal grants and contracts.- Worked on DARPA SHADE, building an HPC-powered OpenAI Gym where researchers built and tested AI bots that to competitively play the strategy game "Diplomacy"- Worked on NIH Acute to Chronic Pain Signatures (a2cps.org), building HIPAA-compliant tracking, logistics, and analysis infrastructure for biological samples from thousands of human subjects - Co-led (2016-2022) Jetstream OpenStack private cloud, which provided user-friendly, self-service interactive computing and data analysis resources to over 3000 users - Co-led CyVerse.org (2008-2022) which provided life sciences data management, collaborative analysis, and resource federation to 100,000+ users- Led infrastructure (2017-21) engineering, development and operations for DARPA Synergistic Discovery and Design (sd2e.org), building scalable, provenance-centered data management and analysis systems that enabled 200+ researchers to develop AI-assisted Design-Build-Test-Learn loops for synthetic biology and solar cell chemistry- Led development and operations of the Araport (2014-2016) federated data ecosystem for unified discovery and query across technically heterogeneous plant genomics and phenotyping resources- Led NSF basic research grants on epigenetic natural diversity, mechanisms of epigenetic gene silencing, and role of heterochromatin in regulating chromosome replication

Responsible for user onboarding and support for University of Texas Research Cyberinfrastructure, covering 13 UT System Institutions across Texas. Led ongoing requirements analysis and prototyping of web service APIs for CyVerse national life sciences infrastructure. Supported life sciences researchers of TeraGrid/XSEDE HPC resources. Led a research group focused on epigenetic natural diversity and mechanisms of epigenetic regulation.

Led ongoing requirements analysis and prototyping of web service APIs for CyVerse national life sciences infrastructure. Supported life sciences researchers of TeraGrid/XSEDE HPC resources.

Led requirements analysis and prototyping efforts for the CyVerse national life sciences infrastructure. Deployed and maintained an HPC-integrated Galaxy server for CSHL Plant Genetics department. Led research on epigenetic natural diversity, mechanisms of epigenetic gene silencing, and role of heterochromatin in regulating plant chromosome replication programs.

Led foundational research on microRNA target prediction and mechanism of molecular silencing, role of small interfering RNA, mechanism and role of gene body DNA methylation, and epigenetic natural diversity. Developed processing and analytical pipelines in support of whole-genome sequencing for variant detection and polyploid genome assembly. Developed large-scale comparative genomics pipelines to drive discovery of candidate genes involved in RNAi and heritable gene silencing.

Recipient of a National Science Foundation Fellowship in Interdisciplinary Informatics. Designed and executed a data-driven research program centered on genome architecture and genetic regulation. Developed processing and visualization pipelines for chromosome-scale genomic tiling microarray data.