Heading up the lab at Edinburgh Genomics. I have a wonderful team of fantastic scientists, built from scratch mostly through various lockdowns; we've come through some tough times but are all the stronger for it.

Managing genomics projects (NGS, arrays, etc.) at Edinburgh Genomics. Upwards of 300 projects per year (~80-100 concurrent projects). Range of Illumina, PacBio, Nanopore projects.

I was responsible for launching Genomics core services at King's College London. Since 2003 I have grown a simple genomics lab into a successful, well-maintained, sustainable, cost-recovering research facility, used by hundreds of researchers, and employing numerous technicians.I provide expert and comprehensive support to dozens of diverse research groups within and external to King's College London, from initial project design through to management and delivery of results. I lead and develop a team of technicians working across multiple campuses to deliver these projects.Recent projects include:Analysis of transcriptional signals in stem cell-derived models of an epidermal barrier - I was able to use powerful software to demonstrate similarities in gene expression patterns between these in vitro cultured cells and their natural counterparts. These models will lead to a better understanding of disease processes and pathologies and may also aid the development of drug development and testing.MicroRNA profiling of liver regeneration - we showed that regulatory microRNA (miRNA) patterns differ significantly between post-transplantation liver regeneration and failure. Processes involving the immune system and cell-cycle/proliferation were found to be most perturbed in this dichotomy of regeneration, allowing a first insight into the molecular nature of liver regeneration.I am solely responsible for experimental design, project management and bioinformatic analysis of resulting genomics data for most of my published studies.

Initiated expression profiling of various haematological malignancies including 5q- MDS, in Dept of Haematological Medicine at King's College Hospital. Liaised with clinicians to organise sample collection with accompanying clinical data. Processing and analysis of samples for whole genome expression profiling using Affymetrix GeneChip microarrays. Developed data analysis skills using genomics software packages. Successfully optimised processing protocols for working with very small clinical samples.