Matthew J Bottomley

Matthew J Bottomley Email and Phone Number

Executive Director, Project Leader and Head of Antigen Design, Vaccines R&D, Dynavax. @ Dynavax Technologies
Matthew J Bottomley's Location
Brookline, Massachusetts, United States, United States
Matthew J Bottomley's Contact Details

Matthew J Bottomley personal email

n/a
About Matthew J Bottomley

I work in Vaccines Research and Development at Dynavax Technologies. I have over 20 years industry experience in both pharmaceuticals and vaccines, previously leading and developing teams at GSK of up to 35 professionals to advance vaccines against multiple bacterial and viral pathogens. My background was initially in structural biology and biochemistry. I aim to drive research through collaborative teams using the best science and technology to accelerate vaccine design and development, with a fundamental passion to improve human health on a global scale.

Matthew J Bottomley's Current Company Details
Dynavax Technologies

Dynavax Technologies

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Executive Director, Project Leader and Head of Antigen Design, Vaccines R&D, Dynavax.
Matthew J Bottomley Work Experience Details
  • Dynavax Technologies
    Executive Director
    Dynavax Technologies Aug 2021 - Present
    Emeryville, Ca, Us
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  • Gsk
    Function Head, Vaccine Design And Cellular Immunology (Preclinical R&D, Us)
    Gsk Jul 2020 - Jul 2021
    Brentford, Middlesex, Gb
    Leadership and management of teams (up to 35 professionals) delivering molecular biology, protein expression, protein purification, protein characterization, protein biophysics, structural biology (x-ray, cryoEM), computational biophysics, cellular immunology, in vivo sciences and high-parametric flow cytometry, all coordinated to support a portfolio of prophylactic and therapeutic vaccines in discovery, development and life-cycle management phases.
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  • Gsk
    Function Head, Vaccine Design And Characterization (Preclinical R&D, Us)
    Gsk Nov 2016 - Jun 2020
    Brentford, Middlesex, Gb
    Leadership and management of teams (up to 16 professionals) delivering protein expression, protein purification and characterization, biophysics and structural biology, to support a portfolio of prophylactic and therapeutic vaccines.
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  • Gsk
    Laboratory Head, Structure-Based Antigen Design, Gsk Vaccines (Preclinical R&D, Italy)
    Gsk Mar 2015 - Nov 2016
    Brentford, Middlesex, Gb
    I led and managed a team of about 10 research scientists. My aim was to apply deep expertise in structural biology to drive the development of novel vaccines to prevent against infectious disease, with a focus on serogroup B meningococcus, C. difficile, staphylococcus aureus, groups A and B streptococcus (GAS, GBS).
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  • Novartis Vaccines And Diagnostics
    Unit Head, Structural Biology
    Novartis Vaccines And Diagnostics Mar 2010 - Feb 2015
    Basel, Baselstadt, Ch
    Leadership and management of a research laboratory focused on structure-based antigen design for vaccines protecting against infectious disease
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  • Merck
    Senior Research Biochemist
    Merck Jan 2006 - Dec 2009
    Rahway, New Jersey, Us
    Structural and functional studies of proteins involved in human disease with the aim to develop therapeutic interventions (e.g. PCSK9).
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  • Irbm
    Research Biochemist
    Irbm 2004 - 2005
    Pomezia, Rome, It
    Structural and functional studies of proteins involved in human disease (e.g. HDAC4).
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  • Irbm
    Marie Curie Research Fellowship (Post-Doc)
    Irbm 2001 - 2003
    Pomezia, Rome, It
    Investigations of the structure and inhibition of bacterial quorum-sensing proteins.
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  • Embl - Heidelberg
    Embo Fellowship (Post-Doc)
    Embl - Heidelberg 1998 - 2001
    Heidelberg, De
    Structural and functional studies of protein domains involved in chromatin structure and regulation.
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Matthew J Bottomley Skills

Protein Chemistry Biochemistry Molecular Biology Protein Expression Purification Structural Biology Vaccines Drug Discovery Protein Purification X Ray Crystallography Signal Transduction Life Sciences Biotechnology Biophysics Surface Plasmon Resonance Nmr Assay Development Nmr Spectroscopy Cell Culture Scientific Writing Lifesciences

Matthew J Bottomley Education Details

  • Ucl
    Ucl
    Biochemistry
  • University Of Oxford
    University Of Oxford
    Biochemistry

Frequently Asked Questions about Matthew J Bottomley

What company does Matthew J Bottomley work for?

Matthew J Bottomley works for Dynavax Technologies

What is Matthew J Bottomley's role at the current company?

Matthew J Bottomley's current role is Executive Director, Project Leader and Head of Antigen Design, Vaccines R&D, Dynavax..

What is Matthew J Bottomley's email address?

Matthew J Bottomley's email address is mj****@****bero.it

What schools did Matthew J Bottomley attend?

Matthew J Bottomley attended Ucl, University Of Oxford.

What skills is Matthew J Bottomley known for?

Matthew J Bottomley has skills like Protein Chemistry, Biochemistry, Molecular Biology, Protein Expression, Purification, Structural Biology, Vaccines, Drug Discovery, Protein Purification, X Ray Crystallography, Signal Transduction, Life Sciences.

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