Matthew Guo Email & Phone Number

Baltimore, Maryland, United States

Internal Medicine resident interested in Hematology/Medical Oncology and Medical Education at the Osler Medical Residency of the Johns Hopkins Hospital

Jarushka Naidoo Laboratory- Elucidated burden of infectious diseases in patients with non-small cell lung cancer treated with immune checkpoint inhibitors to better understand the adverse events that limit treatment with immunotherapy- Presented research findings at the Society for Immunotherapy of Cancer 36th Annual Meeting in 2021

Josephine Feliciano Laboratory- Studied inequalities in care deliveries for newly diagnosed cancer patients transitioning from the inpatient setting to the outpatient clinic at the Johns Hopkins Hospital to better understand areas of improvement for patient care coordination- Characterized the physical, emotional, spiritual, and financial needs for long-term lung cancer survivors to improve knowledge regarding holistic survivorship needs of patients

Kristen Marrone Laboratory- Characterized genomic determinants of response to therapy with definitive chemoradiation and consolidation durvalumab for stage III non-small cell lung cancer to generate improved therapy recommendations by patient tumor mutational landscape- Presented research findings at the Society for Immunotherapy of Cancer 36th Annual Meeting in 2021

Baltimore, Maryland, United States

Lukasz Gondek Laboratory- Investigated patient outcomes following bone marrow transplant for acute myeloid leukemia, correlating patient genotypes of clonal minimal residual disease with relapse-free survival, overall survival, and GvHD-free survival to identify better MRD screening criteria for patients at risk for relapse following BMT- Studied HLA loss of heterozygosity as a mechanism for immune escape and relapse following bone marrow transplant for acute myeloid leukemia- Honored as an American Society of Hematology (ASH) Hematology Opportunities for the Next Generation of Research Scientists (HONORS) awardee for my research in the Gondek lab

Ithaca, New York Area

Robert Weiss Laboratory-Researched the role of the RAD9-HUS1-RAD1 DNA damage repair protein complexes in somatic and meiotic chromosomal maintenance.-Studied the unique chemosensitivity of testicular germ cell tumors to determine underlying mechanisms contributing to chemoresistance in cancers-Maintained mouse colonies and Weiss lab website-Spearheaded the transition of all of the Weiss lab mouse colony records from paper to digital, utilizing the Soft Mouse software. Taught graduate students in the lab how to use software for future mouse colony maintenance

Ithaca, New York

Robert Weiss LaboratoryResearched the role of the RAD9-HUS1-RAD1 DNA damage repair protein complexes in somatic and meiotic chromosomal maintenance.-Wrote senior thesis titled: Canonical and Noncanonical Mammalian 9-1-1 DNA Damage Response Complexes Have Distinct Roles in Both Meiotic and Somatic Chromosomal Maintenance-Analyzed the effects of Rad1 conditional knockout in the testes of mouse using mouse handling and care, immunohistochemistry, and immunofluorescence techniques to determine the role of RAD1 in mammalian meiosis and spermatogenesis.-Characterized mutant-Rad9a mouse embryonic fibroblasts to study the role of the RAD9A protein in DNA damage repair and checkpoint signaling using short term survival, Western blot, clonogenic assay, immunofluorescence staining, and metaphase spread techniques.-Characterized the formation of the noncanonical RAD9-HUS1-RAD1 clamps using molecular cloning, transfection, and co-immunoprecipitation techniques.-Developed a CRISPR-mediated knock-out of ETAA1 in mouse embryonic fibroblasts to study the function of ETAA1-mediated ATR activation in DNA damage repair using lentiCRISPR cloning, viral generation and transduction, and single-cell selection techniques-Presented research findings at the National Conference of Undergraduate Research, the University at Buffalo DNA Replication and Repair Symposium, the Cornell University Undergraduate Research Forum, and the Cornell Inter-Campus Genome Instability, Repair and Editing Symposium-Built and maintained Weiss lab website

Ithaca, New York, United States

Scribed in the emergency department of Cayuga Medical Center, assisting physicians with managing patient flow and completing electronic medical records.-Documented patient history, symptoms, review of systems, diagnosis, lab and imaging results, and medical decision making for input to electronic medical record in the fast paced and professional environment of the emergency room-Assisted physicians in accessing old medical records, laboratory/radiology results, and other important documents relevant for patient care-Received extensive training on medical terminology, proper documentation of medical records, and the work-flow organization within an emergency care facility

Ithaca, New York

Undergraduate teaching assistant for BIOG1445: Introduction to Comparative Anatomy and Physiology, Individualized Instruction-Taught a weekly discussion section-Wrote and proctored oral exam quizzes for one-on-one evaluation of student mastery of material-Tutored students on course material-Led lab session experimenting on plant photosynthesis, led students on rat dissection

Bethesda, Maryland

Yihong Ye LaboratoryResearched the misfolded-associated protein secretion (MAPS) unconventional protein secretion pathway by studying galectin-3 secretion.-Developed a quantitative method to study galectin-3 secretion using cloning techniques-Investigated the regulation of galectin-3 unconventional secretion using cell culture, transfection, siRNA knockdown, Western blot, and CPRG assay techniques-Characterized the signal sequence responsible for unconventional protein secretion using cloning, transfection, and Western blot techniques.-Presented my findings at the NIH Summer Poster Day.

Lectured, held discussion/answer sessions, drafted quizzes and exams, proctored exams, oversaw class labs, graded lab reports and homework assignments

Doctor Of Medicine - Md, Medicine

Activities and Societies: Medical Student Senate, lung cancer and leukemia outcomes research

Bachelor Of Arts (B.A.), Biological Sciences, Summa Cum Laude With Distinction In All Subjects

Activities and Societies: Research Assistant; Cornell Club Swimming; Medicine, Education, and Development for Low Income Families.

Advanced Studies Diploma, Biotechnology Research

Activities and Societies: American Cancer Society Relay for Life, National Honor Society, Varsity Swimming, Science Olympiad