Matt Williams Email & Phone Number

Hillsboro, Oregon, United States

Switzerland 🇨🇭 , Ch

As a seasoned Enterprise Architect, I serve as the key architecture partner for the Pharma Technical Operations division, which encompasses 10 manufacturing sites across North America, Europe, and Asia. My role involves shaping and guiding the architectural vision for these sites, ensuring alignment with broader business goals, and driving innovation and standardization in manufacturing systems and IT processes.Key Responsibilities:• Architectural Strategy & Leadership: Lead the development and execution of current and future architectural landscapes, collaborating closely with ITOT site leaders to align site-specific roadmaps with division-wide strategic objectives.• Manufacturing Execution System (MES) Strategy: Spearhead the MES strategy for the Pharma division, focusing on a core model that ensures centralized development and deployment across multiple sites. Platforms include Rockwell PharmaSuite, Emerson Syncade and Siemens OpCenter.• Standardization & Process Improvement: Drive standardization efforts in both technology platforms and IT processes across global manufacturing sites, enhancing operational efficiency and consistency.• Technical Expertise & Guidance: Act as a thought leader in manufacturing systems, offering strategic guidance on IT solution selection, design, and implementation, while collaborating with stakeholders and external partners to ensure scalability and sustainability.

Switzerland 🇨🇭 , Ch

Ad Interim IT Site Head for Hillsboro Campus, supporting the Drug Product and Cell and Gene Therapies sites, . Performed this role in addition to my architecture responsibilities. - Strategic partner for the business; served as the site liaison to Roche global IT application and service teams. Served as the lead IT member of the Leadership teams for both manufacturing organizations. Served on the regional leadership team for Genentech for the state of Oregon. - Established support models and operational improvements with cloud computing and cybersecurity infrastructure teams. Ensured high availability for IT/OT solutions including MES, Data Historian, Serialization, SCADA, and Building Automation. - Provided IT site leadership in a matrix-environment of IT groups that supported manufacturing applications, intrastructure, devices, and back office infrastruture. Parterned with each distint group in Global IT to ensure operational continuity, and address issues and escaltions. - Collaborated with Site Quality and Engineering to develop local CSV validation processes to support integration with equipment qualification.- Led onboarding and off-boarding activities for local IT members. Key decision maker in the hiring process for open IT positions. - Provided remote IT leadership for the Roched Distribution center in Louisville, Kentucky. Ensured the site maintained overall IT operational status and partnering on new technology initiatives. Provided a single IT contact for issues and escaltions.Key Projects:- Led successful implementation for Industry 4.0 / Cloud computing, including the migration of the Serialization system from legacy infrastructure. - Successfully led Operational Support transition from local site to Global Operations in a "follow the sun" model for manufacturing and quality systems. Negotiated an expedited timeline to address local resource gaps.- Served as IT lead for internal and external audits at both Manufacturing sites.

Switzerland 🇨🇭 , Ch

As a Solution Architect at Roche, I played a pivotal role in supporting the pharmaceutical manufacturing sites. My responsibilities included:- Oversight and Leadership: Supervised consulting resources, providing technical guidance, and ensuring project alignment. Partnered with program leadership to build a sustainable operational support organization.- System Implementation & Optimization: Led the design, implementation, and continuous optimization of MES in drug substance sites worldwide.- Stakeholder Collaboration: Collaborated with Global IT, manufacturing operations, and quality control teams to ensure robust system integration and compliance with industry regulations. Fostered a collaborative environment, driving teamwork and knowledge-sharing.- System Validation: Conducted validation activities, including requirements gathering, change and configuration management, and risk assessments. Ensured implementations complied with regulatory standards.- Core Team Membership: As an original member of the Drug Substance MES Core team, I contributed to strategy development, system enhancements, and best practices for multi-site implementation of MES Syncade.- MES Solution Design: Participated in designing MES solutions to meet operational requirements and improve system capabilities. Key decision-maker in infrastructure design and system integration with enterprise applications (e.g. ERP, LIMS).- Site Infrastructure Implementation: Partnered with the Global Infrastructure team to implement IT and OT systems on the next generation manufacturing infrastructure. Leveraged Nutanix for hyper-converged infrastructure, microsegmentation design, and Roche cybersecurity standards.- Evaluation of AR/VR Solutions: Partnered with Global IT teams to evaluate AR/VR solutions for Roche, collaborating with manufacturing sites, technology providers, and determining key use cases and requirements.

Switzerland 🇨🇭 , Ch

In this role, I supported Genentech Manufacturing sites in Hillsboro, Oregon (Drug Product, Cell and Gene Therapies) as well as the Kentucky Distribution center. - Provided operational support for Manufacturing applications (MES, Serialization) and QC Labs- Stakeholder management with Manufacturing, Quality, Supply Chain, and Automation teams- Developed a strong collaborative partnership with Global Engineering and IT functions to implement infrastructure and applications in the new facility. - Provided leadership to the local Manufacturing IT team. Instituted new ways of working, leveraging agile methodologies. Implemented and facilitated weekly sprint reviews with the team, providing improved transparency to our overall team’s efforts. Evangelized Roche standard collaboration tools to improve team-wide communication. Main Projects: Implementation of Rockwell PhramaSuite MES – key technical resource responsible for delivery of the application to the site. Responsible for design of business services, security authorization strategy, testing strategy, and release management. Implementation of OSIsoft PI Data Historian – partnered with the Global PI team and key influencer to establish a standard Roche platform for PI. Collaborated on common templates for the CSV approach and standard design (leveraging the Global Manufacturing standard infrastructure on Nutanix). Successfully implemented the first site in the manufacturing network. The approach adopted for global implementation, which will provide company savings for 3.8MM CHF per yearCertified in Agile Scrum Master and Product Owner

Lake Oswego, Oregon, Us

- Returned to manufacturing-focused role within newly established Digital Factory Systems team- Program manager for factory’s Manufacturing Execution System (MES) running on the Siemens Camstar platform. - Project Lead for MES upgrade from Camstar 5.8 to Version 7, which includes conversion of UI from Web application to portal, Open Adaptor to CIO, and Oracle 11 to Oracle 12 conversion. - Implemented Oracle Golden Gate on the MES database. which sent MES data to the corporate data lake. Led design of the system to ensure requirements were met and sensitive company information was protected.- Liaison to Regional IT team supporting next-generation technology implementations.- Valued team player; provided extensive knowledge transition before exiting. The knowledge I transferred influenced design and implementation decisions months after I left the organization.

Lake Oswego, Oregon, Us

- Member of IT PMO; responsible for management of the IT project portfolio.- Drove improves to IT project management quality and project on-time delivery. - Mentored junior project leads to improve overall consistency of project management. - Maintained key business relationships with R&D department (SPOC), partnering with leadership to implement IT solutions for next-generation product development - partnered with corporate IT teams including Service Delivery, Collaboration, Infrastructure Services, and Manufacturing to influence local interests.Key Projects:- Project Manager to replace all Oracle Database Hardware for the region. Led a team of internal and consulting resources on project execution to ensure accuracy and delivery. Coordinated with multiple business teams to ensure accuracy of cutover with minimal system downtime.- Regional Lead for the corporate upgrade to Windows 10. Worked with corporate teams to ensure regional interests were covered. Advised global teams on best practices and global design aspects, ensuring overall success for the project.

Lake Oswego, Oregon, Us

- Served as MES (Siemens Camstar) Lead functional consultant and adminstrator in a highly automated environment. - Level 1 DBA support for the company's Oracle (11g) and SQL Server environments, including support for the MES transactional and reporting databases. Administrator for Business Objects environment (3.1 and 4.2), used for MES Reporting- Project Manager and Lead Architect to upgrade MES from Camstar 4.3 to Camstar 5.8. Led a cross-functional team from the Quality, IT, Engineering, Supply Chain, and Operations. Responsible for test design and execution. Transitioned infrastructure from physical to virtual machines. Executed factory-wide cutover with minimal downtime and impact to operations. Directly responsible for ensuring the project was delivered on time and in budget.- Developed a MES training program to support all functions (basic and advanced), aligning with role-based security.- Co-project lead to select next-generation equipment integration platform (ZNT pac). Led vendor selection process, developed user requirements, and partnered with the Global MES team to standardize the solution.Additionally took on responsibilities outside of MES for the IT Operations team- Led a team of IT analysts to implement improvements in IT operations. Led standardization efforts for an organization of ~1500 end users and ~3000 endpoints. - IT Process owner for departmental Change Management Board. Oversaw and led change management process covering Infrastructure and Enterprise Applications. - Developed and implemented Global IT processes in areas including Security, Onboarding, Change Management, Software testing and Computer Systems Validation.

Fridley, Minnesota, Us

- Program manager for implementation of a Global SPC application built on the Camstar MES Platform. Supported 2000+ users at 30+ sites in NA, EMEA, and APAC. Led team of internal and consulting resources on the initial implementation and software upgrade projects. - Developed and maintained key relationships with the Global Operational Excellence Team. Provided voice of customer to the IT organization, and successfully advocated for funding to improve the global SPC solution.- Worked with internal customers to develop reporting requirements for operational excellence initiatives. Designed and implemented a BI Solutions using SQL Server Reporting Services integrated with SharePoint. - Responsible for functional and user requirements gathering, as well as use case and test development for FDA for multiple regulated computer systems. Responsible for the Computer Systems Validation plan, and led the overall execution (IQ/OQ/PQ) on multiple projects and applications. - Presented at multiple conferences and user groups on topics related to MES, SPC, and Software Validation.

Fridley, Minnesota, Us

- IT Site Lead for manufacturing applications in a highly automated 24x7 environment.- Direct management for a team that included FT and PT employees. Responsible for hiring, firing, goal, and objective setting, performance reviews- Implemented a custom factory automation application. Led an external consulting team through multiple iterations of development and enhancements to provide a robust solution for the factory.- Implemented a custom factory-wide automation application reporting on downtime and waste. - Developed custom BI applications implemented in 4 factories in the division - Supported corporate selection and implementation teams for Maximo and Warehouse Management- Primary administrator for the site ERP (BPCS)

Bachelor Of Science - Bs, Computer And Systems Engineering

Master Of Science - Ms, Business Intelligence And Analytics