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Highly accomplished molecular biologist in the field of neuroscience. Research has primarily utilized genetically engineered mice to discover the function of a particular gene in the brain. Capable of being an independent, as well as team-oriented researcher, that is proficient in a wide variety of experimental techniques used in neuroscience research. My Google Scholar Profile: https://scholar.google.com/citations?hl=en&user=CyS9tTkAAAAJ&view_op=list_works
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Senior Research AssociateAltos Labs May 2024 - Present -
Research Associate IiAltos Labs Jan 2023 - Apr 2024
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Research Associate IAltos Labs Aug 2022 - Dec 2022
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SpecialistUniversity Of California, San Francisco Oct 2017 - Jun 2022San Francisco, California, Us- Created several mutant mouse lines and demonstrated that two Familial Natural Short Sleepers (FNSS) alleles are strong genetic modifiers of Alzheimer’s Disease pathology and may confer resilience to the progression of neurodegeneration- Designed and performed in vitro assay to validate the mutation found in human FNSS and investigate their mechanism of action- Contributed to many high-quality peer-reviewed publications, not only from the lab, but also collaborative projects- Supervised and mentored graduate students, summer school students, and research associates -
Postdoctoral ScholarUniversity Of California, San Francisco Jan 2015 - Oct 2017San Francisco, California, Us- Created several Cre knock-in and point mutation mouse lines by CRISPR technology to study short sleep phenotype in vivo- Established high-throughput (384-well plate format) genotyping system using qPCR- Acquired mouse brain surgery technique for EEG and in vivo calcium imaging to record sleep/wake state in mouse brain
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Postdoctoral ScholarUniversity Of California, San Francisco Oct 2011 - Dec 2014San Francisco, California, Us- Participated in a research project to understand the molecular mechanism of synaptic plasticity based on the regulation of glutamate receptors- Created conditional knockout mice by crossing with Purkinje cell specific Cre mouse and performed electrophysiological experiments. The project was completed in collaboration with Genentech.- Trained in electrophysiological techniques (whole-cell patch clamp) to record synaptic responses from mouse neurons- Acquired the skill of mouse cerebellar acute slices and neuronal primary culture for electrophysiological recording- First authored a research article which appeared in top peer-reviewed scientific journals
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Assistant Professor (Instructor)Brain Research Institute, Niigata University Apr 2005 - Sep 2011- Participated in a research project involving the molecular mechanism of synaptic plasticity based on the interaction of AMPA-type glutamate receptors and TARPs (transmembrane AMPA receptor regulatory proteins)- Generated TARPs gamma-2 and gamma-7 knockout mice and demonstrated that both proteins cooperatively promote synaptic expression of cerebellar AMPA receptors- Created Diacylglycerol lipase (DGL) alpha and beta knockout mice and demonstrated first that 2-AG produced by DGLalpha is a ubiquitous retrograde messenger at central synapses - Involved in teaching at the bench, supervising/mentoring graduate students and technicians- Collaborated with researchers in Japan and abroad on multiple projects (mostly related to the generation of genetically engineered mice)
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Research Fellow Of The Japan Society For The Promotion Of ScienceHokkaido University School Of Medicine Apr 2004 - Mar 2005Jp
Maya Yamazaki Skills
Maya Yamazaki Education Details
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Niigata UniversityNeuroscience -
Niigata UniversityMolecular Biology
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Niigata UniversityBiology
Frequently Asked Questions about Maya Yamazaki
What company does Maya Yamazaki work for?
Maya Yamazaki works for Altos Labs
What is Maya Yamazaki's role at the current company?
Maya Yamazaki's current role is Senior Research Associate at Altos Labs.
What is Maya Yamazaki's email address?
Maya Yamazaki's email address is ma****@****csf.edu
What schools did Maya Yamazaki attend?
Maya Yamazaki attended Niigata University, Niigata University, Niigata University.
What skills is Maya Yamazaki known for?
Maya Yamazaki has skills like Molecular Biology, Cell Biology, Fluorescence Microscopy, Biochemistry, Neuroscience, Immunohistochemistry, In Vivo, Genetic Engineering, Transgenic Mice, Animal Behavior, Mouse Handling, Cell Culture.
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