Associate Professor Of Pharmacology
CurrentTeaching Pharmacology, Pharmacogenomics of Oncology & Drug Discovery and Development.Navigating the software package R in order to finish a paper.
Jun 2013 - Present
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Mchardy Smith Email & Phone Number
Assoc Professor of Molecular Pharmacology
at
LECOM - Bradenton
1 work email found
@lecom.edu
3 phones found area 732 and 908
LinkedIn matched
✓ Verified August 2026
4 data sources
Profile completeness 100%
Current company
Role
Assoc Professor of Molecular Pharmacology
Location
Bradenton, Florida, United States
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Who is Mchardy Smith? Overview
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Mchardy Smith is listed as Assoc Professor of Molecular Pharmacology at LECOM - Bradenton, a with 96 employees, based in Bradenton, Florida, United States. AeroLeads shows a work email signal at lecom.edu, phone signal with area code 732, 908, and a matched LinkedIn profile for Mchardy Smith.
Mchardy Smith previously worked as Associate Professor of Pharmacology at Lecom - Bradenton and Visiting Full Professor at University Of The Sciences. Mchardy Smith holds Postdoctoral Fellow, Cell Biology/Biochemistry from Washington University School Of Medicine In St. Louis.
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{first_initial}{last}@lecom.edu
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Profile bio
About Mchardy Smith
Professor of Pharmacology. Teaching pharmacology and toxicology to graduate students, Pharm D candidates and to BS Pharmacology and Toxicology students. Focus is on communicating technical information by using student's existing frames of reference and active learning. Responsible for curriculum development and course design.Senior Research Scientist in Membrane Biochemistry & Biochemical Pharmacology. Skilled leader with over 20 years industry experience at Merck & Co. Committed to focused drug discovery and development through teamwork and critical thinking with a record of success from discovery to preclinical. Experienced in membrane based mechanisms across most therapeutic areas including animal health and crop protection applications. Major driver of Medicinal Chemistry and HTS campaigns.Relocation is not an issue.Specialties:HTS/uHTS assay development & follow-up for medicinal chemistry programsIndustrial grade statistical tools for assay quality controlDirecting, mentoring and guiding researchProtein purification: 1ary, 2ary, 3ary & 4ary structure determinationG-protein coupled receptorsLigand-gated & Voltage-gated ion channels Enzyme hysteresis, slow binding & irreversible inhibitorsLigand binding, ELISA & enzymatic assays, Immunochemistryhttp://www.ncbi.nlm.nih.gov/myncbi/1jaPhdKxmeiAi/cv/994/
Listed skills include Drug Discovery, Assay Development, Biochemistry, Pharmacology, and 33 others.
Current workplace
Mchardy Smith's current company
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6 roles · 33 years
Mchardy Smith work experience
A career timeline built from the work history available for this profile.
Visiting Full Professor
Course Coordinator for Pharmacology I and for Biochemical Pharmacology and ToxicologyTeaching Pharmacology and Toxicology.Also taught at Middlesex County College, teaching Human Anatomy and Physiology.Navigating the software package R in order to finish a paper.Mentoring and curriculum development at Students2Science, a science-enrichment program giving middle and high school students real laboratory experiences.
Aug 2011 - Jun 2013
Sr Research Fellow
Biochemical experimentation leading towards clinical drug discovery. Continued work on Nodulisporic acid receptor in invertebrates. Continued work on peptide toxin blockers of Kv2.1 (GxTx-I) and Nav 1.7 (ProTx-II). Finished up HTS campaign on Nav 1.7 using FLIPR and VIPR using FRET dyes. Started an N-type calcium channel screening campaign including counterscreening using FLIPR 384 and Ca dyes.Scientific lead in developing a basic research data analysis tool adopted company-wide. Major driver in writing "Fluorescent plate readers: Merck Best Practices".
2000 - 2008
~8 yrs
Research Fellow
Identified the mechanism of action of a novel fungal product (nodulisporic acid) with insecticidal activity - it potentiated the opening of the invertebrate glutamate-gated chloride channel. I also found that the Drosophila melanogaster Glutamate-gated chloride channel co-immunoprecipitated with a subunit of the GABA-gated chloride channel. Ran three HTS campaigns on nodulisporic acid and Ivermectin binding sites in invertebrates.Setup and ran a high-throughput screening (HTS) assay using the human sodium channels Nav 1.7 and 1.8 on a VIPR using FRET dyes. Purified and determined the primary and secondary structure of spider toxins blocking Nav 1.7 and Kv2.1. They are cystine-knot peptides that block by shifting the voltage-dependence of channel activation to a more positive potential.Led program to automate reading of larval death assays. Ended a 6 yr term on Merck Research Laboratories Rahway Site Safety Committee with last yr as Chair of same.
1994 - 2000
~6 yrs
Senior Research Biochemist
From spider venom, I identified several activities of interest. I purified to homogeneity an invertebrate-selective sodium channel activator and several calcium channel blockers. Activities were traced by functional assays, electrophysiological assays and by conotoxin binding assays. Proteins were purified by reverse phase and Ion exchange HPLC. Purified peptides and proteins were used as proof-of-concept molecules and as tools for basic science research. Purified proteins were sequenced.The HPLC data was acquired using a program built in LabVIEW. The program monitored and recorded absorbance (up to 4 wavelengths), back pressure and %B, and controlled 2 fraction collectors.
Sep 1988 - 1994
Postdoctoral Fellow
Biosynthesis and Assembly of the subunits of the nicotinic Acetylcholine receptor in the lab of Dr. John Paul Merlie. Also studied phosphorylation of the nicotinic acetylcholine receptor in intact cells in the lab of Dr. John Lawrence.
Jun 1984 - Aug 1988
3 education records
Mchardy Smith education
Postdoctoral Fellow, Cell Biology/Biochemistry
Ph.D., Pharmacology
B. A., Psychology
FAQ
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What company does Mchardy Smith work for?
Mchardy Smith works for LECOM - Bradenton.
What is Mchardy Smith's role at LECOM - Bradenton?
Mchardy Smith is listed as Assoc Professor of Molecular Pharmacology at LECOM - Bradenton.
What is Mchardy Smith's email address?
AeroLeads has found 1 work email signal at @lecom.edu for Mchardy Smith at LECOM - Bradenton.
What is Mchardy Smith's phone number?
AeroLeads has found 3 phone signal(s) with area code 732, 908 for Mchardy Smith at LECOM - Bradenton.
Where is Mchardy Smith based?
Mchardy Smith is based in Bradenton, Florida, United States while working with LECOM - Bradenton.
What companies has Mchardy Smith worked for?
Mchardy Smith has worked for Lecom - Bradenton, University Of The Sciences, Merck, and Washington University School Of Medicine.
How can I contact Mchardy Smith?
You can use AeroLeads to view verified contact signals for Mchardy Smith at LECOM - Bradenton, including work email, phone, and LinkedIn data when available.
What schools did Mchardy Smith attend?
Mchardy Smith holds Postdoctoral Fellow, Cell Biology/Biochemistry from Washington University School Of Medicine In St. Louis.
What skills is Mchardy Smith known for?
Mchardy Smith is listed with skills including Drug Discovery, Assay Development, Biochemistry, Pharmacology, Protein Chemistry, Cell, Enzyme Assays, and Western Blotting.
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