Associate Professor Of Pharmacology
CurrentTeaching Pharmacology, Pharmacogenomics of Oncology & Drug Discovery and Development.Navigating the software package R in order to finish a paper.
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@lecom.edu
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Mchardy Smith is listed as Assoc Professor of Molecular Pharmacology at LECOM - Bradenton, a company with 96 employees, based in Bradenton, Florida, United States. AeroLeads shows a work email signal at lecom.edu, phone signal with area code 732, 908, and a matched LinkedIn profile for Mchardy Smith.
Mchardy Smith previously worked as Associate Professor of Pharmacology at Lecom - Bradenton and Visiting Full Professor at University Of The Sciences. Mchardy Smith holds Postdoctoral Fellow, Cell Biology/Biochemistry from Washington University School Of Medicine In St. Louis.
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Professor of Pharmacology. Teaching pharmacology and toxicology to graduate students, Pharm D candidates and to BS Pharmacology and Toxicology students. Focus is on communicating technical information by using student's existing frames of reference and active learning. Responsible for curriculum development and course design.Senior Research Scientist in Membrane Biochemistry & Biochemical Pharmacology. Skilled leader with over 20 years industry experience at Merck & Co. Committed to focused drug discovery and development through teamwork and critical thinking with a record of success from discovery to preclinical. Experienced in membrane based mechanisms across most therapeutic areas including animal health and crop protection applications. Major driver of Medicinal Chemistry and HTS campaigns.Relocation is not an issue.Specialties:HTS/uHTS assay development & follow-up for medicinal chemistry programsIndustrial grade statistical tools for assay quality controlDirecting, mentoring and guiding researchProtein purification: 1ary, 2ary, 3ary & 4ary structure determinationG-protein coupled receptorsLigand-gated & Voltage-gated ion channels Enzyme hysteresis, slow binding & irreversible inhibitorsLigand binding, ELISA & enzymatic assays, Immunochemistryhttp://www.ncbi.nlm.nih.gov/myncbi/1jaPhdKxmeiAi/cv/994/
Listed skills include Drug Discovery, Assay Development, Biochemistry, Pharmacology, and 33 others.
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Bradenton, FL
Teaching Pharmacology, Pharmacogenomics of Oncology & Drug Discovery and Development.Navigating the software package R in order to finish a paper.
Greater Philadelphia Area
Course Coordinator for Pharmacology I and for Biochemical Pharmacology and ToxicologyTeaching Pharmacology and Toxicology.Also taught at Middlesex County College, teaching Human Anatomy and Physiology.Navigating the software package R in order to finish a paper.Mentoring and curriculum development at Students2Science, a science-enrichment program giving.
Biochemical experimentation leading towards clinical drug discovery. Continued work on Nodulisporic acid receptor in invertebrates. Continued work on peptide toxin blockers of Kv2.1 (GxTx-I) and Nav 1.7 (ProTx-II). Finished up HTS campaign on Nav 1.7 using FLIPR and VIPR using FRET dyes. Started an N-type calcium channel screening campaign including.
Identified the mechanism of action of a novel fungal product (nodulisporic acid) with insecticidal activity - it potentiated the opening of the invertebrate glutamate-gated chloride channel. I also found that the Drosophila melanogaster Glutamate-gated chloride channel co-immunoprecipitated with a subunit of the GABA-gated chloride channel. Ran three HTS.
From spider venom, I identified several activities of interest. I purified to homogeneity an invertebrate-selective sodium channel activator and several calcium channel blockers. Activities were traced by functional assays, electrophysiological assays and by conotoxin binding assays. Proteins were purified by reverse phase and Ion exchange HPLC. Purified.
Biosynthesis and Assembly of the subunits of the nicotinic Acetylcholine receptor in the lab of Dr. John Paul Merlie. Also studied phosphorylation of the nicotinic acetylcholine receptor in intact cells in the lab of Dr. John Lawrence.
Studied Post-translational processing and phosphorlyation of the nicotinic Acetylcholine receptor
Activities and Societies: Graduate student Representative to Honor CourtDissertation Title: Muscarinic receptor-mediated attenuation of.
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Mchardy Smith works for LECOM - Bradenton.
Mchardy Smith is listed as Assoc Professor of Molecular Pharmacology at LECOM - Bradenton.
AeroLeads has found 1 work email signal at @lecom.edu for Mchardy Smith at LECOM - Bradenton.
AeroLeads has found 3 phone signal(s) with area code 732, 908 for Mchardy Smith at LECOM - Bradenton.
Mchardy Smith is based in Bradenton, Florida, United States while working with LECOM - Bradenton.
Mchardy Smith has worked for Lecom - Bradenton, University Of The Sciences, Merck, and Washington University School Of Medicine.
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Mchardy Smith holds Postdoctoral Fellow, Cell Biology/Biochemistry from Washington University School Of Medicine In St. Louis.
Mchardy Smith is listed with skills including Drug Discovery, Assay Development, Biochemistry, Pharmacology, Protein Chemistry, Cell, Enzyme Assays, and Western Blotting.
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