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Martin C. is listed as Research Scientist - Medicinal Chemistry (Contractor) at Vertex Pharmaceuticals, based in San Diego, California, United States. AeroLeads shows a work email signal at gnf.org and a matched LinkedIn profile for Martin C..
Martin C. previously worked as Scientist I - NMR Spectroscopy at Gnf and Associate Scientist - Analytical Chemistry (Contractor) at Celgene. Martin C. holds Bachelor Of Science, Chemistry, Minor In German from Uc Irvine.
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AeroLeads found 1 current-domain work email signal for Martin C.. Compare company email patterns before reaching out.
A Research Chemist with expertise in Medicinal and Analytical Chemistry involved in drug discovery within the Biotech and Pharmaceuticals industries.KEY TECHNICAL SKILLS• Multi-Step Small Molecule & Oligo Organic Synthesis • HPLC, UPLC, SFC, LC-MS, LC-MS/MS, NMR• GC, GC-MS, CE (with dynamic coating), CGE, FT-IR(ATR), XRD, KF, TGA-DTA/DSC• Structure Elucidation by NMR Spectroscopy • Software: ChemStation, Empower Pro, MassHunter, Chromeleon, Analyst, Xcalibur, Bruker TopSpin, ACD/NMR Workbook, MestReNova, ChemBioDraw, E-Notebook • Extensive work in the synthesis of novel Small-Molecule Heterocyclic Organic Compounds, Carbohydrate Chemistry, Nucleosides/Nucleotides, and Oligonucleotide/DNA synthesis• Experienced in Drug Design, Synthetic Method Development, Hit-to-Lead & Lead-Optimization processes with a firm understanding of biology• Ability to analyze SAR and ADME-Tox data to improve potency and efficacy of compounds as modulators of GPCRs• Wide experience ranging from small scale Parallel Synthesis of compound libraries to large scale (2 kg) syntheses of Product Development Candidates.• Synthesized heterocyclic compound libraries targeting GPCRs involved in cardiovascular, central nervous system, inflammatory, and metabolic (obesity, diabetes) diseases. • Performed Structure Elucidation by NMR Spectroscopy (H, C, HMQC, COSY, NOESY, ROESY, HMBC experiments and interpretations) (400MHz, 500MHz, & 600MHz).Analytical Chemistry: Developed and Validated analytical testing methods to identify Small Molecules utilizing modern analytical techniques including HPLC, UPLC, LC-MS/MS, NMR, GC, GC-IR/MS, FT-IR(ATR), IR-Microscopy, Raman, CE (with dynamic coating), and XRD in an ISO/IEC 17025:2005 accredited laboratory. Maintained instruments. Federal Security Clearance Level: Top Secret Extensive publication record in peer reviewed Journals and Patents.Interested in Medicinal Chemistry, Synthetic Organic Chemistry, Analytical Chemistry and R&D.Specialties: • Agilent 1100/1200 Series HPLC• Waters ACQUITY UPLC• Thermo Finnigan LCQ Advantage MAX Quadrupole Ion-Trap MS, ESI + APCI source, Surveyor HPLC, Xcalibur software (LC-MS/MS, LC-MSn)• Agilent 6890N Series GC, GC-MS• Varian Pro/Prep Star HPLC• Shimadzu-AB/MDS Sciex LC-MS• Bruker Avance 400/500/600MHz NMR• Biotage Initiator Microwave SynthesizerMedicinal/Synthetic/Analytical/Process Chemistry; Structure Elucidation by NMR; Drug Discovery; Parallel Synthesis; Nucleoside, Nucleotide, DNA Synthesis; R&D
Listed skills include Gc, Spectroscopy, Drug Design, Gas Chromatography, and 25 others.
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Boston, MA, US
Planned and conducted multi-step organic syntheses incorporating modern lab bench techniques to produce heterocyclic small molecules for SAR studies in order to research Competitive Intelligence of lead compounds in the area of pain management (NaV1.8).
San Diego, CA, US
Performed molecular measurements and analysis utilizing 400MHz, 500MHz, & 600MHz NMR Spectroscopy (Proton, Carbon, HMQC, COSY, ROESY, NOESY, HMBC) for Structure Elucidation of small molecules in support of GNF Medicinal Chemistry, maintained open access Bruker 400MHz, 500MHz, & 600MHz NMR instruments, incorporated LC/MS and HPLC in amino acid analysis..
Summit, New Jersey, US
Performed Analytical Method Development, Purification, and Analysis of small molecule chiral and achiral compounds using HPLC and SFC with multiple detectors including UV, ELSD and MS (single Quad & QQQ) to assist Medicinal Chemistry efforts. Conducted quantitative analysis of compounds and stability studies using HPLC techniques with existing methods.
ALD/CVD Semiconductor Materials Chemistry. Synthetic Organometallic Chemistry under inert atmosphere conditions (glovebox, Schlenk lines, high vacuum systems). Synthesized, purified, and analyzed organic ligands and their metal complexes for use in ALD/CVD within the semiconductor industry. Incorporated GC, GC-MS, HPLC with ChemStation, NMR, Karl-Fischer.
San Diego, CA, US
Performed molecular measurements and analysis utilizing 400MHz & 600MHz NMR Spectroscopy (Proton, Carbon, HMQC, COSY, ROESY, HMBC) for Structure Elucidation in support of GNF Chemistry, maintained Bruker 400MHz NMR instrument and BIAcore instrument for protein interaction analysis, executed Protein Expression and Purification incorporating SDS-PAGE and.
Developed and validated analytical testing methods to identify and quantify small molecules/controlled substances utilizing modern analytical techniques including UPLC, HPLC, LC-MS/MS, GC, GC-IR/MS, FT-IR(ATR), IR-Microscopy, Raman, CE (with dynamic coating), NMR, and XRD in an ISO/IEC 17025:2005 accredited laboratory. Maintained instruments. Instrument.
San Diego, CA, US
Performed research in new Oligonucleotide/DNA synthesis methods; DNA shearing; Surface Chemistry and contact angle measurementsutilizing Waters - ACQUITY UPLC®, HPLC, PerSeptive Biosciences - Expedite™ 8909 Nucleic Acid Synthesis System, Agilent 2100 Bioanalyzer with DNA 12000 Kit (DNA Chip), NanoDrop Spectrophotometry. Instrument software: Chromeleon.
San Diego, CA, US
Planned and conducted multi-step organic syntheses incorporating modern lab bench and microwave assisted synthesis techniques to produce heterocyclic compound libraries for SAR studies of lead compounds targeting GPCRs to identify their SAR trends and interpret their data, utilized online databases to search scientific literature to determine synthetic.
Conducted chemical process research for the scale-up of Arena compound AR234442. Utilized Powder X-Ray Diffraction, TGA-DTA/DSC, and Microscope techniques to characterize crystal structures of target compounds.
Conducted multi-step organic syntheses of ribosyl and heterocyclic modified nucleosides, nucleotides, and DNA sequences (utilizing Expedite 8909 Nucleic Acid Synthesis Systems) with enhanced antisense properties and RNA-cleaving functionalities for inhibiting RNA activity, as well as combinatorial chemistry libraries and examined SARs of active compounds.
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Martin C. works for Vertex Pharmaceuticals.
Martin C. is listed as Research Scientist - Medicinal Chemistry (Contractor) at Vertex Pharmaceuticals.
AeroLeads has found 1 work email signal at @gnf.org for Martin C. at Vertex Pharmaceuticals.
Martin C. is based in San Diego, California, United States while working with Vertex Pharmaceuticals.
Martin C. has worked for Vertex Pharmaceuticals, Gnf, Celgene, Air Products & Chemicals, Inc., and Genomics Institute Of The Novartis Research Foundation (Gnf).
You can use AeroLeads to view verified contact signals for Martin C. at Vertex Pharmaceuticals, including work email, phone, and LinkedIn data when available.
Martin C. holds Bachelor Of Science, Chemistry, Minor In German from Uc Irvine.
Martin C. is listed with skills including Gc, Spectroscopy, Drug Design, Gas Chromatography, Sfc, Hplc, Organic Synthesis, and Uplc.
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