Megan Settle Email & Phone Number

• Direct the building and design of the R&D and microbiology laboratory from the ground up.
• Design laboratories to meet all biosafety, personal protective requirements and to maintain the stability of raw components and finished products.
• Oversee the selection of equipment and materials
• Develop and maintain work flow process to streamline batch production from raw materials to finished products to microbiological testing.
• Create FDA-compliant standard operating procedures from scratch
• Challenge test products to determine viability of the preservatives used.

Cleveland/Akron, Ohio Area

• Determine and execute methods for improving the safety, efficacy, tolerability, and overall quality of the compounded medications currently produced.
• Develop compliance guidelines and standard operating procedures according to Pharmacy State Board regulations, FDA regulations and the U.S. Pharmacopeia.
• Underwent FDA, California, and Ohio inspections, both for opening the pharmacy in a new location and annual inspections.
• Collaborative research with outside institutions. Ensuring all goals were accomplished according to grant proposals in correlation with our set compliance standards.
• Research, suggest and implement equipment and methods that improve efficiency in the preparation and packaging of medications; including capsules, emulsions/lotions and syrups.
• Work closely with outside testing laboratories to ensure that the potency and stability of the medications tested is performed correctly.

Cleveland/Akron, Ohio Area

• Human Heart transplant processing
• Performed and analyzed RT-PCR on Affymetrix platform
• Conducted biofeedback analysis
• Laboratory Techniques Gained & Utilized: ∙ Transporting and dissecting whole hearts and left ventricular device cores for experimentation and storage.∙ Removed trabecular muscles for experimentation∙ Performed.

Cleveland/Akron, Ohio Area

• Teaching undergraduate students molecular biology. Writing and implementing lectures and exams. Topics covered
• Mitosis
• Protein translation
• Meiosis
• Regulation of gene expression
• Chromosomal inheritance

• I performed various experiments in relation to molecular cardiology. The main focus of my laboratory research was studying kindlins 2 and 3 in relation to integrins. Working in a multicultural environment allowed me to.
• Manage mouse colony of over 60 specific backgrounds
• Handle adverse events within the colony regarding genomic problems, health issues and breeding issues
• Work with multiple doctors as support for transgenic design, experiment design and implementation
• Monitor and report the experimental progress
• Maintain colony records and report to Internal Review Board

• Coordinated execution of assigned protocols in accordance with research governing entity
• Collaborated with primary investigator, and research staff to plan, conduct and evaluate project protocols
• Monitor and report on progress of projects
• Assisted with recruitment, selection and monitoring of research project participants
• Trained in handling adverse events and compliance issues
• Assists with responding to and preparing for audits

Pathology And Laboratory Medicine Institute

• Skilled in Epic, Copath, and Navicare patient information systems
• Skilled in data analysis utilizing GraphPad Prism and Excel software
• Developed and implemented novel procedures for laboratory
• Skilled in writing standard operating procedures for laboratory
• Trained residents and fellows in laboratory procedures
• Trained in automated immunohistochemistry staining and manual staining

• Trained incoming employees and students
• Radioactive training
• Trained in the left arterial descending ligation surgery in mice
• Specifically trained in the removal and isolation of aortic endothelial and smooth muscle cells
• Laboratory Techniques Gained & Utilized: ∙Lipid metabolism ∙Cellular lipid efflux
• ELISA∙Primary mouse macrophage cultures ∙Immunohistochemistry∙Fluorescent microscopy ∙PCR cycle sequencing∙Fluorescent and chemiluminescence imaging ∙Western blotting∙Agarose gel electrophoresis ∙Sterile techniques for.

• Provided research support in molecular studies to determine the effects of Type I and Type II diabetes in transgenic mice
• Laboratory Techniques Gained & Utilized:∙DNA quantification ∙Labeled DNA probes ∙Non- radioactive DNA sequencing ∙cDNA library screening∙Non-radioactive signal detection ∙Made DIG probes by PCR∙Nucleic acid.

• Assisted thirty-five residents in a floor section
• Coordinated educational programs, promoted a community, and administered university policies

Masters Of Biology, Molecular Biology

Advancements in Molecular Biology Biochemistry Biomedical Physiology Chromosome Structure and Function - Graduate Seminar; Science in.

Bachelor Of Science, Microbiology

Molecular Genetics - Quantitative Analysis - Laboratory Genetics - Pathogenic Bacteriology - Microbial Physiology - Immunology - Microbial.