Mehrdad (Mike) Shadmehr

Mehrdad (Mike) Shadmehr Email and Phone Number

Supervisor of Formulation and Manufacturing at Thermo Fisher Scientific @ Thermo Fisher Scientific
Mehrdad (Mike) Shadmehr's Location
Pleasanton, California, United States, United States
Mehrdad (Mike) Shadmehr's Contact Details

Mehrdad (Mike) Shadmehr personal email

About Mehrdad (Mike) Shadmehr

I am an organic chemist with extensive experience with design, synthesis, purification (including different types of chromatography), and characterization (including different types of instrumental analysis) of small molecules and fluorescent probes for chemical biology, drug delivery, and medicinal chemistry purposes. ​I also have experience with bioconjugation of small molecules for fluorescent labeling of peptides and proteins.

Mehrdad (Mike) Shadmehr's Current Company Details
Thermo Fisher Scientific

Thermo Fisher Scientific

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Supervisor of Formulation and Manufacturing at Thermo Fisher Scientific
Mehrdad (Mike) Shadmehr Work Experience Details
  • Thermo Fisher Scientific
    Supervisor Of Formulation And Manufacturing
    Thermo Fisher Scientific Sep 2023 - Present
    Waltham, Ma, Us
    •Lead and manage a team of fifteen senior and junior chemists in production and process development of fluorescent dyes, quenchers, nucleotides, and linkers for multiple projects in the genetic science division of Thermo Fisher Scientific and external customers.
  • Theracea Pharma
    Technology Consultant
    Theracea Pharma Dec 2022 - Present
    Oro Valley, Arizona, Us
  • International Journal Of Nanomedicine
    Editorial Board Member
    International Journal Of Nanomedicine Jun 2020 - Present
  • Asian Journal Of Nanosciences And Materials
    Member Of Review Panel
    Asian Journal Of Nanosciences And Materials Jun 2018 - Present
  • Proteogenomics Research Institute For Systems Medicine (Prism)
    Research Scientist (Bioconjugation Chemistry)
    Proteogenomics Research Institute For Systems Medicine (Prism) Apr 2023 - Sep 2023
    La Jolla , Us
    •Design and synthesis of novel linker for Antibody-drug conjugates (ADCs).•Synthesis, purification, and characterization of ADCs via Dialysis, SEC-UV, MALDI, etc.
  • Thermo Fisher Scientific
    Scientist Iii
    Thermo Fisher Scientific Nov 2021 - Dec 2022
    Waltham, Ma, Us
    •Design and synthesis of small molecules fluorophores and quenchers (multi-step synthesis).•Purification of small molecules applying different types of chromatography methods including TLC, Flash Chromatography, HPLC, UPLC, UPLC-MS.•Characterization of small molecules by different types of instrumental spectroscopy methods including NMR, MS, UV-Vis, Fluorometry.
  • University Of Virginia
    Postdoctoral Research Associate
    University Of Virginia Aug 2019 - Nov 2021
    Charlottesville, Va, Us
    • Design and synthesis of small molecule fluorogenic fluorophores.• Design and synthesis of second window near-infrared fluorophores.
  • Cient Periodique Medicine (Cpq Medicine)
    Member Of The Editorial Board
    Cient Periodique Medicine (Cpq Medicine) Jul 2018 - Jun 2020
  • University Of Nebraska-Lincoln
    Postdoctoral Research Associate
    University Of Nebraska-Lincoln Jan 2018 - Jul 2019
    Lincoln, Ne, Us
    • Design and synthesis of small molecule fluorogenic fluorophores.• Design and synthesis of second window near-infrared fluorophores.• Design and synthesis of photoactivatable fluorogenic prodrug fluorophores as a drug delivery system for small anticancer molecules.• Purification of small molecules applying different types of chromatography methods including TLC, Flash Chromatography, HPLC, LCQ.• Characterization of small molecules by different types of instrumental spectroscopy methods including NMR, MS, UV-Vis, Fluorometry, IR.• Toxicity test of small molecules on different types of cell lines including Hela, Cho, and Raw cells.• Scale-up synthesis of different types of small molecule up to 50 grams.• Applying different types of software for interpretation data and prediction including ChemDraw, Chem3D, Mestrenova, Excel, etc. • Applying scientific search engines for design and discovery of new and economical synthetic routes including SciFinder, Reaxys, PubMed, etc.• Volunteer Judge of undergraduate research symposium.
  • Herald Scholarly Open Access Journal Of Medicine
    Member Of The Editorial Board
    Herald Scholarly Open Access Journal Of Medicine Jun 2018 - Jun 2019
  • Journal Of Scientia Iranica
    Member Of Review Panel Section C (Chemistry)
    Journal Of Scientia Iranica Mar 2018 - Mar 2019
  • The University Of Arizona
    Research And Teaching Assistant
    The University Of Arizona Aug 2011 - Dec 2017
    Tucson, Arizona, Us
    • Design and synthesis of the Triazabutadiene-based coumarins and its application for fluorescent labeling of Tyrosine residues of proteins.• Design and synthesis of the coumarin-triazabutadiene as a cross-linker and a fluorophore pull-down system for characterization and purification of peptides, proteins, and Nucleic acids.• Design and synthesis of Dual-Functional triazabutadiene for surface modification. • Design and synthesis of cleavable bioorthogonal affinity tag for protein purification.• Design and synthesis of the smallest photoactive cyclooctadiyne.• Design and synthesis of a borane protected phosphine triazabutadiene as a new Staudinger reagent for Tyrosine labeling of proteins.• Design and synthesis of a cleavable fluorogenic system including Cyclooctyne triazabutadiene and azido coumarin for Tyrosine modification of proteins.• Scale-up synthesis of small molecules and fluorophores into gram scale up to 100 grams.• Purification of small organic molecules by different methods including Recrystallization, Flash chromatography, Prep-TLC, GC, HPLC, Lyophilization. • Characterization of organic small molecules by different types of instrumental analysis methods including NMR, 2D NMR, IR, GC, GC-MS, React-IR, MS, LC-MS, UV-Vis• Scale-up synthesis of different types of small molecule up to 50 grams.• Applying different types of software for interpretation data and prediction including ChemDraw, Chem3D, Mestrenova, Excel, etc. • Applying scientific search engines for design and discovery of new and economic synthetic routes including SciFinder, Reaxys, PubMed, etc.• Mentoring and training undergraduate researcher and new graduate students• Research assistant of NMR facility, helping for the maintenance of all of the NMR machines of chemistry and biochemistry department, running samples of undergraduate and graduate level teaching labs.• Teaching undergraduate and graduate level of organic chemistry and organic chemistry labs
  • Icagen
    Organic Chemist Intern
    Icagen Jul 2016 - Aug 2016
  • Sanofi
    Organic Chemist Intern
    Sanofi May 2016 - Aug 2016
    Paris, France, Fr
    • Synthesis of a library of drug candidate organic small molecules (piperazinone derivatives) for PMP22 inhibition as a therapeutic approach for Charco-Marie-Tooth disease type 1A.• Purification and characterization of organic small molecules applying different instrumental methods including Chromatography, HPLC, LC-MS, NMR.• Applying different types of software for interpretation data and prediction including ChemDraw, Chem3D, Mestrenova, Excel, etc. • Applying scientific search engines for design and discovery of new and economical synthetic routes including SciFinder, Reaxys, PubMed, etc.
  • Southern Illinois University Edwardsville
    Research And Teaching Assistant
    Southern Illinois University Edwardsville Feb 2009 - Jun 2011
    Edwardsville, Illinois, Us
    • Design and synthesis of a library of a fluorinated bioactive small heterocyclic molecule (fluoro-isoxalidine and fluoro-pyrrolidine).• Purification of small organic molecules by different methods including Recrystallization, Flash chromatography, Prep-TLC, GC. • Characterization of small organic molecules by different types of instrumental analysis methods including NMR, 2D NMR, IR, GC, MS, UV-Vis.• Applying different types of software for interpretation data and prediction including ChemDraw, Chem3D, Mestrenova, Excel, ACD lab. • Applying scientific search engines for design and discovery of new and economic synthetic routes including SciFinder, Reaxys, PubMed, etc.• Mentoring and training undergraduate researcher and new graduate students.• Teaching undergraduate level of general chemistry and organic chemistry labs.
  • University Of Tehran
    Research And Teaching Assistant
    University Of Tehran Oct 2004 - Aug 2008
    Tehran, Tehran, Ir
    Research Assistant Synthesis of Azalactone Via Darzene type reactions Teaching Assistant, Biochemistry lab, undergraduate levelTeaching Assistant Nutrition Chemistry lab, undergraduate level

Mehrdad (Mike) Shadmehr Skills

Nmr Organic Chemistry Uv/vis Chemistry Organic Synthesis Spectroscopy Analytical Chemistry Mass Spectrometry Hplc Medicinal Chemistry Chromatography Biochemistry Bioorthogonal Chemistry Research Bioorganic Chemistry Assistant Teaching Fluorescence Science Microsoft Office React Ir Nuclear Magnetic Resonance Characterization Uv/vis Spectroscopy Lc Ms Drug Discovery Microwave Purification High Performance Liquid Chromatography Liquid Chromatography Mass Spectrometry Synthetic Organic Chemistry Higher Education Mentoring Teaching Pharmaceutical Industry Teamwork Leadership Training Cell Culture Toxicity Lyophilization

Mehrdad (Mike) Shadmehr Education Details

  • University Of Arizona
    University Of Arizona
    Organic Chemistry
  • Southern Illinois University Edwardsville
    Southern Illinois University Edwardsville
    Fluorine Chemistry
  • University Of Tehran
    University Of Tehran
    Chemistry

Frequently Asked Questions about Mehrdad (Mike) Shadmehr

What company does Mehrdad (Mike) Shadmehr work for?

Mehrdad (Mike) Shadmehr works for Thermo Fisher Scientific

What is Mehrdad (Mike) Shadmehr's role at the current company?

Mehrdad (Mike) Shadmehr's current role is Supervisor of Formulation and Manufacturing at Thermo Fisher Scientific.

What is Mehrdad (Mike) Shadmehr's email address?

Mehrdad (Mike) Shadmehr's email address is me****@****her.com

What schools did Mehrdad (Mike) Shadmehr attend?

Mehrdad (Mike) Shadmehr attended University Of Arizona, Southern Illinois University Edwardsville, University Of Tehran.

What are some of Mehrdad (Mike) Shadmehr's interests?

Mehrdad (Mike) Shadmehr has interest in Science And Technology, Education, Chemistry.

What skills is Mehrdad (Mike) Shadmehr known for?

Mehrdad (Mike) Shadmehr has skills like Nmr, Organic Chemistry, Uv/vis, Chemistry, Organic Synthesis, Spectroscopy, Analytical Chemistry, Mass Spectrometry, Hplc, Medicinal Chemistry, Chromatography, Biochemistry.

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