Michael Cicirelli, Phd
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Michael Cicirelli, Phd Email & Phone Number

Senior Director, Small Molecule Discovery at Omeros Corporation at Omeros Corporation
Location: Seattle, Washington, United States 8 work roles 3 schools
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Role
Senior Director, Small Molecule Discovery at Omeros Corporation
Location
Seattle, Washington, United States
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Who is Michael Cicirelli, Phd? Overview

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Michael Cicirelli, Phd is listed as Senior Director, Small Molecule Discovery at Omeros Corporation at Omeros Corporation, a company with 279 employees, based in Seattle, Washington, United States. AeroLeads shows a matched LinkedIn profile for Michael Cicirelli, Phd.

Michael Cicirelli, Phd previously worked as Senior Director, Small Molecule Discovery at Omeros Corporation and Director of High Throughput Screening at Theroclone Sciences (Formerly Spaltudaq). Michael Cicirelli, Phd holds Post-Doc With Ed Krebs At The Howard Hughes Medical Institute, Protein Biochemistry from University Of Washington.

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Omeros Corporation

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About Michael Cicirelli, Phd

I have been working for over 30 years in the Biotechnology industry, applying laboratory automation to high throughput screening of small molecules libraries, developing rapid turnaround assay panels for selectivity & ADMET to speed SAR cycle times, building custom auxiliary devices and writing custom programs for automating data analysis, data management and compound inventory/distribution. I have worked on developing microarray applications for HT SPR instrumentation, applied microarrays for antibody screening and have developed research products for the biotech industry.

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Michael Cicirelli, Phd's current company

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Omeros Corporation
Omeros Corporation
Senior Director, Small Molecule Discovery at Omeros Corporation
seattle, washington, united states
Website
Employees
279
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8 roles · 36 years

Michael Cicirelli, Phd work experience

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Senior Director, Small Molecule Discovery

Current

Seattle, Washington, United States

- Directed a small team of scientists to screen a 370K diversity library against ~50 orphan GPCR targets using a cell redistribution assay run on an automated robotics system with high content imaging instruments- Led the development and screening of several HTS assays against complement system serine proteases and lectin pathway assays- Wrote numerous VBA.

Dec 2010 - Present

Director Of High Throughput Screening

Theroclone Sciences (Formerly Spaltudaq)

Seattle, Washington, United States

- Successfully set up a laboratory to print high density microarrays- Employed microarray technology for the HT screening of antibodies produced from activated B-cell clones.- Directed the capture of human antibodies on slide surfaces and developed assays for sensitive detection of specific antibodies, as well as total IgG- Directed screening against a.

Jul 2008 - Dec 2010

Director, Microarray Development

Plexera (Formerly Lumera)

Seattle, Washington, United States

Developed microarray applications for a high throughput microarray Surface Plasmon Resonance instrument, capable of measuring binding of proteins and small molecules to a maximum of 5000 arrayed spots simultaneously in real time. - Tested the capabilities of early prototype instruments and provided feedback on the fuluidics, optics and software design, as.

Jul 2006 - Jun 2008

Director, Research

Icos

Seattle, Washington, United States

Director, Research (2001-2006) - Directed a team of 6 highly experienced scientists to continue running HTS and develop additional capabilities, adding value to the company - Led a group effort to develop and run routine automated assays for solubility, chemical stability, metabolism, permeability (Caco2), serum protein binding, and hERG - wrote extensive.

2001 - Feb 2006

Associate Director, Research

Icos

Bothell, Washington, United States

Managed a team of five talented technical scientists and RAs - performed HTS on a wide variety of biochemical and cell- based targets (~80 total) - procured and screened diverse synthetic libraries, combinatorial libraries, natural products, focused libraries, and peptidomimetics (~300,000 compounds)

1997 - 2001 ~4 yrs

Senior Staff Scientist, Research

Icos

Bothell, Washington, United States

Established and managed HTS program, trained RAs - Helped research groups develop "automation-friendly" and "kinetically-correct" assays for HTS - Devised and employed compound pooling strategy - procured and programmed robotic systems for formatting compounds and running HTS - Set up a storage facility for library compounds -wrote software for analyzing.

1994 - 1997 ~3 yrs

Staff Scientist, Research

Icos

Bothell, Washington, United States

- Developed robust automation-friendly radiometric assay for PDEs - Refolded PDEs from inclusion bodies and characterized their enzyme kinetic properties - Became involved in strategic planning for a small molecule screening program

1992 - 1994 ~2 yrs

Research Staff Scientist

Life Technologies, Inc.

Gaithersburg, Maryland, United States

- R&D, transfer of technologies to operations, technical support, product planning, teaching, writing protocols, manuscripts and catalog copy- overexpressed protein kinases and PDEs in Ecoli and engineered them for facilitated protein purification- purified proteins and wrote up detailed protocols- developed assay kits for protein kinases and phosphatases.

1990 - 1992 ~2 yrs
Team & coworkers

Colleagues at Omeros Corporation

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3 education records

Michael Cicirelli, Phd education

Doctor Of Philosophy - Phd, Developmental Biology (Mentor: Dr L.D. Smith)

FAQ

Frequently asked questions about Michael Cicirelli, Phd

Quick answers generated from the profile data available on this page.

What company does Michael Cicirelli, Phd work for?

Michael Cicirelli, Phd works for Omeros Corporation.

What is Michael Cicirelli, Phd's role at Omeros Corporation?

Michael Cicirelli, Phd is listed as Senior Director, Small Molecule Discovery at Omeros Corporation at Omeros Corporation.

Where is Michael Cicirelli, Phd based?

Michael Cicirelli, Phd is based in Seattle, Washington, United States while working with Omeros Corporation.

What companies has Michael Cicirelli, Phd worked for?

Michael Cicirelli, Phd has worked for Omeros Corporation, Theroclone Sciences (Formerly Spaltudaq), Plexera (Formerly Lumera), Icos, and Life Technologies, Inc..

Who are Michael Cicirelli, Phd's colleagues at Omeros Corporation?

Michael Cicirelli, Phd's colleagues at Omeros Corporation include Jenee Hsiung, Jordan Feltus, Kelly Nebel Rn, Steve Russo, and Tina Quinton.

How can I contact Michael Cicirelli, Phd?

You can use AeroLeads to view verified contact signals for Michael Cicirelli, Phd at Omeros Corporation, including work email, phone, and LinkedIn data when available.

What schools did Michael Cicirelli, Phd attend?

Michael Cicirelli, Phd holds Post-Doc With Ed Krebs At The Howard Hughes Medical Institute, Protein Biochemistry from University Of Washington.

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