Michael Dyson

Michael Dyson Email and Phone Number

Vice President, Antibody Discovery and Engineering @ Ichnos Glenmark Innovation
Lausanne, VD, CH
Michael Dyson's Location
Lausanne, Vaud, Switzerland, Switzerland
Michael Dyson's Contact Details

Michael Dyson work email

Michael Dyson personal email

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About Michael Dyson

Mike Dyson is Head of the Antibody Discovery and Engineering Department at Ichnos Glenmark Innovation, responsible for the development of novel multi-specific immune engager therapeutics to treat cancer. Mike is an experienced project manager, leading multi-disciplinary teams for several successful therapeutic antibody drug discovery projects resulting in 9 biologics (antibody or bi-specific format) to commence human clinical trials or approaching IND filing to treat cancer or auto-immune diseases. Projects collaborations included Janssen, Takeda, BMS, Sanofi, Teva, F-star, Adaptate, GammaDelta, Epsilogen, Astria, Agenus, INOTREM, LG Chem, Generium, plus one third of the top 20 Pharma. He has experience in co-founding start-up companies, being a key founding team member during their growth phase and operating as an R&D manager in more mature, larger publicly listed companies in addition to VC backed companies. He has published 40 papers and book chapters (cited over 2000 times, h-index 20) and is inventor on 16 patent and patent applications mainly focussed on novel antibody therapeutics, antibody formats or discovery platforms. Previous posts held by Mike include CTO and co-founder of IONTAS Ltd, a therapeutic antibody discovery and development company, Head of Protein Engineering at Acambis plc (acquired by Sanofi) and was a Project Leader at the Wellcome Trust Sanger Institute. He has extensive experience in the multi-disciplinary enabling antibody discovery and development technologies including library generation, antibody and scaffold phage and mammalian display, in silico design and engineering, assay development, cell line engineering, protein sciences and pre-clinical development. He has successfully applied for several grants from the EU, UK and various charities. He has a PhD in organic synthetic chemistry from the University of Birmingham and has held research posts at the Massachusetts Institute of Technology and the Universities of Edinburgh and Cambridge.

Michael Dyson's Current Company Details
Ichnos Glenmark Innovation

Ichnos Glenmark Innovation

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Vice President, Antibody Discovery and Engineering
Lausanne, VD, CH
Michael Dyson Work Experience Details
  • Ichnos Glenmark Innovation
    Vice President, Antibody Discovery And Engineering
    Ichnos Glenmark Innovation
    Lausanne, Vd, Ch
  • Ichnos Glenmark Innovation
    Vice President, Antibody Discovery And Engineering
    Ichnos Glenmark Innovation Jul 2023 - Present
    New York, Ny, Us
  • Ichnos Glenmark Innovation
    Senior Director - Head Of Antibody Display Technologies
    Ichnos Glenmark Innovation Jul 2020 - Jun 2023
    New York, Ny, Us
  • Iontas Ltd
    Chief Technology Officer
    Iontas Ltd Sep 2015 - Jun 2020
    Porto, Porto, Pt
  • Iontas Ltd
    Co-Founder And Project Leader
    Iontas Ltd Oct 2012 - Sep 2015
    Porto, Porto, Pt
    www.iontas.co.uk
  • University College London
    Principal Research Associate
    University College London Apr 2012 - Sep 2012
    London, Greater London, Gb
    Short placement in Kerry Chester and Tony Ng labs developing antibodies for cancer diagnostics.
  • University Of Cambridge
    Senior Research Associate
    University Of Cambridge Oct 2007 - Mar 2012
    Cambridge, England, Gb
    The application of antibodies for mapping signal transduction cascades was explored with the Tony Pawson and Dev Sudhu labs (Toronto). The ability to directly screen for antibody function in stem cells was exemplified in several publications by combining gene targeting with phenotypic screening. This led to the development of the antibody mammalian display platform. Cancer Research UK, Welcome Trust and Newton Trust grants enabled several therapeutic antibody discovery projects.
  • Wellcome Trust Sanger Institute
    Project Leader
    Wellcome Trust Sanger Institute Jul 2002 - Sep 2007
    Hinxton, Cambridgeshire, Gb
    I led the Protein Sciences Team within the core Welcome Trust funded Atlas of Protein Expression project to enable HTP antibody generation for genome wide proteomic applications including mapping by immunohistochemistry (IHC). Expression systems were introduced to enable the expression of protein families and new methods for structural domain boundary mapping. HTP methods were developed to enable novel extra cellular receptor interaction mapping including the cloning, expression and purification of all murine type 1 receptors. Collaborations were initiated with several structural genomics groups including the Structural Genomics Consortium and the Harvard Institute of Proteomics with Josh La Baer.
  • Sense Proteomic
    Group Leader - Research Projects
    Sense Proteomic Jan 2001 - Jun 2002
    Austin, Texas, Us
    I led the Research Projects team developing novel methods for the creation and interrogation of protein microarrays. This included the development of a P52 SNP chip and P450 array for drug toxicology screening.
  • Acambis Research Limited
    Head Of Protein Engineering
    Acambis Research Limited Jun 1997 - Jan 2001
    Headed a small team where phage display libraries were used to generate peptide mimotope vaccines for for auto-immune disease, Group B meningitis and RSV. Leads were optimised by affinity maturation to neutralising antibodies, SPR screening and testing in various in vitro and in vivo pre-clinical models. The the anti- IgE allergy vaccine project was in collaboration with GSK Vaccines, Rixensart and resulted in patent filings.
  • University Of Edinburgh
    Research Fellow
    University Of Edinburgh Jan 1992 - Jun 1997
    Edinburgh, Gb
    In research group of the inventor of the Hepatitis B vaccine and co-founder of Biogen Inc - Professor Sir Kenneth Murray. I studied the mechanism of assembly of Hepatitis B virus. Phage display libraries were used to map protein-protein interactions important for viral assembly and identify inhibitors of virus assembly including binder affinity maturation in the early period of phage display.

Michael Dyson Skills

Lifesciences Biotechnology Drug Discovery Genomics Molecular Biology Antibodies Bioinformatics Biochemistry Proteomics Monoclonal Antibodies Protein Expression Biomarker Discovery Cell Culture Protein Chemistry Assay Development Cell Cell Biology High Throughput Screening In Vitro Life Sciences Phage Display Immunology Drug Development

Michael Dyson Education Details

  • Massachusetts Institute Of Technology
    Massachusetts Institute Of Technology
    Department Of Biology
  • University Of Birmingham
    University Of Birmingham
    Organic Synthetic Chemistry
  • University Of Birmingham
    University Of Birmingham
    Chemistry
  • Tewkesbury School
    Tewkesbury School

Frequently Asked Questions about Michael Dyson

What company does Michael Dyson work for?

Michael Dyson works for Ichnos Glenmark Innovation

What is Michael Dyson's role at the current company?

Michael Dyson's current role is Vice President, Antibody Discovery and Engineering.

What is Michael Dyson's email address?

Michael Dyson's email address is md****@****m.ac.uk

What schools did Michael Dyson attend?

Michael Dyson attended Massachusetts Institute Of Technology, University Of Birmingham, University Of Birmingham, Tewkesbury School.

What skills is Michael Dyson known for?

Michael Dyson has skills like Lifesciences, Biotechnology, Drug Discovery, Genomics, Molecular Biology, Antibodies, Bioinformatics, Biochemistry, Proteomics, Monoclonal Antibodies, Protein Expression, Biomarker Discovery.

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