Michael Kalos Email and Phone Number
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Michael Kalos personal email
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I am an expert in T cell therapy and immunotherapy with 30 years of experience in cell therapy, immunooncology and oncology vaccines, and bring extensive scientific and operational expertise to these fields. I am the Founder and Managing Director at Next Pillar Consulting, where I provide consulting and advising services in the biopharmaceutical and venture space. Additionally, I am a Senior Venture Partner and Head of Cell Therapy for Orange Grove Bio, an integrated biopharmaceutical company dedicated to developing therapies to improve patient lives; at Orange Grove Bio I serve as the CEO of the subsidiary company IpiNovyx. I also serve on Corporate Board of Directors and Scientific Advisory Boards for various public and private biopharmaceutical companies.Over the span of my career I have held C-suite, executive, and leadership roles in several organizations. These roles include Executive Vice President and Head of R&D at ArsenalBio where I led the R&D and product development strategy for the company’s first product; Vice President of Immuno-Oncology and Oncology Cell Therapies at Janssen, where I led internal and external corporate strategies in cell therapy, neoantigen vaccines, and immuno-oncology; and Chief Scientific Officer of Immunooncology at Eli Lilly and Company where I established and integrated internal and external strategies in immunooncology, including biologics, bi-specifics, vaccines, and cell therapy.Before joining the biopharmaceutical sector, I spent 10 years in academia where I established and lead translational laboratories at City of Hope and the University of Pennsylvania. At the University of Pennsylvania I founded and directed the Translational and Correlative Studies Laboratory where my team developed the paradigm for translational research in cell therapy and played a pivotal role in the early development of the CTL019 program that led to the approval of Kymriah (tisagenlecleucel).I earned my PhD from the University of Minnesota and completed post-doctoral training in the laboratory of Phil Greenberg at the Fred Hutchinson Cancer Research Center. Over the course of my career, I have co-authored over 85 peer-reviewed manuscripts, including numerous high-impact and field-defining articles, and hold 32 issued patents in cell therapy, immunotherapy, and vaccines. I am also an active advisory member for several international immunotherapy consortia and societies, and frequently speak at national and international scientific meetings.
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Executive Venture PartnerAlloy Therapeutics, Inc.Philadelphia, Pa, Us
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Chief Executive OfficerIpinovyx Bio Aug 2024 - PresentCincinnati, Ohio, UsIpiNovyx Bio is a Cincinnati-based subco of Orange Grove Bio, focused on the development of novel proteasome inhibitors for the treatment of cancer and autoimmune diseases -
Senior Venture Partner And Head Of Cell TherapyOrange Grove Bio May 2022 - PresentCincinnati, Ohio, UsOrange Grove Bio is focused on creating high-impact companies through university partnerships to accelerate drug development for treating cancer, autoimmune, and inflammatory diseases. Venture partners take leadership roles in the sourcing, diligence assessment, establishment, and operation of new companies established under the Orange Grove umbrella. -
Managing DirectorNext Pillar Consulting, Llc Sep 2020 - PresentRecognized thought leader in cell, vaccine, and checkpoint -based immunotherapy and translational/early clinical biomarker development, with strong record of building and leading immunotherapy programs in biopharma and academic settings. Extensive experience and expertise enabling organizations to successfully establish R&D strategies and develop clinically relevant immune therapies.• 85+ peer reviewed primary and review articles, including seminal and high-impact first-in-man studies that defined the cell therapy landscape for CAR-T and TCR-T; New England Journal of Medicine, Nature, Nature Medicine, Immunity, Science Translational Medicine, Clinical Cancer Research, Annual Reviews Immunology, Blood.• Strategic and operational planning and implementation• R&D infrastructure and quality establishment• External partnerships- strategy and business development• Mechanistic and translational biomarker development • In-vitro and in-vivo immunooncology assay and model development• Clinical biomarker design and implementationR&D subject matter expertise:• Oncology Cell Therapy (CART, TCRT).• Oncology Vaccines (Neoantigens, TCR discovery)• Immunooncology (Checkpoints, Agonists, bi-specifics)• Translational and clinical biomarkers
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Founding Chief Scientific OfficerCtrl Therapeutics Jun 2022 - Aug 2023San Francisco, UsMember Executive leadership team and Board of Directors. Established and led corporate R&D strategy and operations; hired initial R&D team. -
Executive Vice President And Head Of R&DArsenalbio Sep 2019 - Sep 2020South San Francisco , Ca, UsMember, Executive leadership teamEstablished Development organization in rapid growth start-up companyDrove R&D and product development strategy for first ArsenalBio product -
Vice President, Immunooncology And Oncology Cell TherapiesThe Janssen Pharmaceutical Companies Of Johnson & Johnson Mar 2018 - Aug 2019Raritan, New Jersey, UsLeader, Immunooncology Pathway area strongholdMember, Oncology senior leadership teamEstablished corporate strategy to consolidate and expand immunotherapy programEstablished corporate strategy in Cell TherapyLed corporate strategy for neoantigen targeting vaccine platformDrove external corporate strategy in immuno-oncology and cell therapy -
Chief Scientific Officer, Cancer Immunobiology, Distinguished Lilly ScholarEli Lilly And Company Nov 2013 - Mar 2018Indianapolis, Indiana, UsMember, Lilly Global Leadership CouncilEstablished corporate strategy for immunotherapy; delivered 5 assets into clinical development Established external corporate strategy and efforts in immunotherapy: Immunore-Ltd (2014); BioNTech-AG (2015); Curevac (2018), multiple academic collaborations Led Cancer Immunobiology Department; R&D, in-vivo and biomarker platforms to mechanistically interrogate pipeline and combinations -
Adjunct Associate Professor, Founding Director, Translational And Correlative Studies LaboratoryUniversity Of Pennsylvania School Of Medicine Dec 2008 - Nov 2013Pa, UsEstablished cGLP laboratory to develop to support clinical and translational T cell immunotherapy studies in immunotherapy.Defined principles and platforms for clinical biomarker assessment of cell therapy productsMember Overall Joint Steering Committee, UPenn-Novartis allianceMember Global Project Team for commercialization of CTL019, UPenn-Novartis alliance -
Associate Professor, Founding Director Of The Clinical Immunobiology Corrrelative Studies LaboratoryCity Of Hope Mar 2004 - Dec 2008Duarte, Ca, UsEstablish and direct a GLP level research laboratory focused on development and application of a broad spectrum of correlative study platforms to support clinical and translational studies -
Senior ScientistCorixa Corporation 1997 - 2004
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Postdoctoral FellowFred Hutchinson Cancer Research Center 1990 - 1997Seattle, Wa, Us
Michael Kalos Skills
Michael Kalos Education Details
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University Of Minnesota Medical SchoolMicrobiology -
University Of MinnesotaBiochemistry
Frequently Asked Questions about Michael Kalos
What company does Michael Kalos work for?
Michael Kalos works for Alloy Therapeutics, Inc.
What is Michael Kalos's role at the current company?
Michael Kalos's current role is Executive Venture Partner.
What is Michael Kalos's email address?
Michael Kalos's email address is mk****@****bal.net
What is Michael Kalos's direct phone number?
Michael Kalos's direct phone number is +120675*****
What schools did Michael Kalos attend?
Michael Kalos attended University Of Minnesota Medical School, University Of Minnesota.
What skills is Michael Kalos known for?
Michael Kalos has skills like Immunology, Cancer, Flow Cytometry, Biotechnology, Molecular Biology, Cell, Translational Research, Life Sciences, Vaccines, Cancer Research, Lifesciences, Biomarkers.
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