Michael Scherz Email and Phone Number
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Mike is a seasoned pharma R&D professional with proven success inventing, assessing, and developing small molecule therapeutics for global Pre-Clinical and Clinical Development ventures. He is the founder of Metys Pharmaceuticals AG, which was sold to Novaremed AG in September 2021.Mike has thirty years of experience and extensive expertise in preclinical, clinical and regulatory matters of global drug development programs for small molecules across therapeutic areas of Neuroscience, Immunology, Cardiovascular, and Endocrinology. He is a committed and trust-worthy leader of global development teams, with proven decision-making abilities. His persistent and accomplished pitch-writing and presenting raising venture funding and non-dilutive grants from private, corporate and government funding sources. Mike is a senior pharma R&D expert inspired by the creative application of novel ideas to improve and widen therapeutic options for patients. He is capable of unifying complex teams and inspiring their collaborative and cooperative advancement of sophisticated development efforts. He is able to grasp and communicate complex, high-volume scientific and business data to diverse audiences.Mike is passionate about the past success and the future promise of rational drug design and development.Mike managed the drug development and drug discovery activities at Metys Pharmaceuticals, and spear-headed the company’s search for investors. He was co-inventor for Metys’ MP-101, a re-patented orally-active Phase 2-ready glutamate signaling modulator; MP-101 is now in preparation for a Phase 2 clinical trial for prevention of chemotherapy-induced sensory symptoms of peripheral neuropathy. He is also co-inventor for MP-102, a patent-pending non-racemic mixture of the levetiracetam enantiomers (intended for use in epilepsy & seizures); and for MP-103, a patent-pending non-racemic mixture of the unifiram enantiomers (intended for use in pain or depression).Mike was vice president and life cycle leader at Actelion, leading multi-disciplinary drug development teams from preclinical to Phase 3 stages of development. Prior to Actelion, Mike was section head of cardiac research at Procter & Gamble Pharmaceuticals in Cincinnati, Ohio, USA; and post-doc in the CNS drug discovery chemistry group at Hoffman-La Roche AG in Basel, Switzerland. Mike graduated in 1989 from the University of Oregon with a PhD in synthetic and medicinal chemistry.
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Co-FounderArphamid Therapeutics Gmbh Sep 2023 - Present -
Consultant, Drug Development & DiscoveryFreelance Sep 2021 - PresentMetys Pharmaceuticals was sold to Novaremed, who are preparing the Phase 2 clinical trials of MP-101 for prevention of oxaliplatin-induced symptoms of peripheral sensory neuropathy.
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Founder & CeoMetys Pharmaceuticals 2013 - PresentBasel, Basel City, ChI created Metys Pharmaceuticals to develop MP-101 for the prevention of chemotherapy-induced painful peripheral neuropathy. In the US alone, in a single year, more than 400'000 patients suffer from the neuropathy caused by their life-saving cancer treatment. No drug has been approved to prevent or treat these symptoms. MP-101 is a newly-repatented, orally active, small molecule: it consists of a 3-to-1 mixture of the right- and the left-handed enantiomers of dimiracetam. We have licensed the world-wide exclusive rights to the ICH-compliant dossier of racemic dimiracetam (i.e. the 1-to-1 mixture of enantiomers), containing more than 200 human subjects' safety and tolerability data, plus toxicology data supporting indefinite human dosing in clinical trials. The FDA have consented to the use of the racemic data - without bridging studies - to support the Phase 2 clinical trials of MP-101. MP-101 is highly effective in preventing and treating symptoms of peripheral neuropathy in rodents and in a non-human primate model. We have prepared the first dedicated efficacy studies of MP-101, and are seeking investors to fund the effort - €20 million are needed. Successful completion of the Phase 2 studies will lead to a trade sale to major pharma; recent similar transactions have been valued in in excess of €300 million. -
Vp, Life CycleActelion Pharmaceuticals Jul 2003 - Dec 2012Basel, ChGlobal development team leader for palosuran (urotensin II receptor antagonist), almorexant (orexin receptor antagonist), ACT-280778 (L/T calcium channel blocker), and ponesimod (S1P1 receptor modulator) • Led team effort for each product to elaborate the vision, the target product positioning, the list of targeted claims and the corresponding development strategy, based on regulatory and commercial requirements; and to then implement the development plan • Represented the life cycle team at Actelion’s senior-most management boards on issues of product positioning and development strategy, and was the accountable person to these boards on issues of timing and costs -
Vp, Drug DiscoveryActelion Pharmaceuticals Sep 2000 - Jun 2003Basel, ChExecutive drug discovery management. Created business plan and research strategy for an envisioned US-based Actelion drug discovery organization, to expand the scope and the talent pool of Actelion’s drug discovery capabilities. -
Section Head, Cardiac ResearchProcter & Gamble Pharmaceuticals 1991 - 2000Cincinnati, Ohio, UsDepartment head responsible for cardiac arrhythmia and heart failure drug discovery research. Expert in voltage-gated potassium channel pharmacology; matrix metalloproteinase inhibitors; vascular endothelial growth factor inducers; cardiac gene expression profiling. -
ChemistF. Hoffmann-La Roche 1989 - 1991Switzerland 🇨🇭 , ChDrug design and synthesis of NMDA/glycine receptor antagonists and channel blockers; and orally active, brain-penetrating acetylcholine esterase inhibitors. -
Graduate Student, ChemistryUniversity Of Oregon 1984 - 1989
Michael Scherz Skills
Michael Scherz Education Details
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University Of OregonOrganic And Medicinal Chemistry -
University Of OregonSynthetic & Medicinal Chemistry -
Lee UniversityChemistry -
Lee CollegeChemistry -
Limes Gymnasium, WelzheimPhysics -
Limes Gymnasium, Welzheim, GermanyPhysics
Frequently Asked Questions about Michael Scherz
What company does Michael Scherz work for?
Michael Scherz works for Arphamid Therapeutics Gmbh
What is Michael Scherz's role at the current company?
Michael Scherz's current role is Co-Founder, Arphamid Therapeutics GmbH.
What is Michael Scherz's email address?
Michael Scherz's email address is mi****@****ion.com
What schools did Michael Scherz attend?
Michael Scherz attended University Of Oregon, University Of Oregon, Lee University, Lee College, Limes Gymnasium, Welzheim, Limes Gymnasium, Welzheim, Germany.
What skills is Michael Scherz known for?
Michael Scherz has skills like Clinical Development, Pharmaceutical Industry, Drug Discovery, Clinical Trials, Medicinal Chemistry, Clinical Pharmacology, Lifesciences, Drug Development, Biotechnology, Regulatory Affairs, Cro, Pharmacovigilance.
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