Michael Wester

Michael Wester Email and Phone Number

Research Fellow I at Vertex Pharmaceuticals @ Vertex Pharmaceuticals
boston, massachusetts, united states
Michael Wester's Location
San Diego, California, United States, United States
Michael Wester's Contact Details
About Michael Wester

Drug metabolism and drug safety scientist with a passion for helping drug discovery projects choose the best compounds to turn into new medicines and development teams to clear regulatory hurdles to bring these medicines to patients. I believe that my efforts as a line manager and mentor to develop colleagues to their fullest potential is the best way to ensure a high performing team that can positively impact drug projects.Key Skills & Experience: DMPK-

Michael Wester's Current Company Details
Vertex Pharmaceuticals

Vertex Pharmaceuticals

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Research Fellow I at Vertex Pharmaceuticals
boston, massachusetts, united states
Website:
vrtx.com
Employees:
3561
Michael Wester Work Experience Details
  • Vertex Pharmaceuticals
    Research Fellow I
    Vertex Pharmaceuticals Jul 2014 - Present
    Greater San Diego Area
    Serve as DMPK project lead for discovery and development projects and lead the high-throughput ADME team.
  • Astrazeneca
    Principal Scientist, Discovery Safety Specialist, Drug Safety & Metabolism
    Astrazeneca Sep 2013 - Jul 2014
    Mölndal, Sweden
    Discovery Safety project representative in the Respiratory and Inflammation therapeutic area. In addition, responsible for in-licensing due diligence and target safety assessments for new targets in the therapeutic area.
  • Astrazeneca
    Associate Director, In Vitro In Silico Adme, Global Dmpk
    Astrazeneca 2012 - Aug 2013
    Mölndal, Sweden
    Lead a team of in vitro ADME scientists providing high-throughput ADME data for the global organization. Included accountability for in silico ADME and outsourced DMPK assays.
  • Astrazeneca
    Associate Director, In Vitro Screening & Profiling, Global Dmpk
    Astrazeneca 2011 - 2012
    Mölndal, Sweden
    Lead a high performing team of in vitro ADME scientists providing high-throughput ADME and physiochemical properties data for the global organization. Lead team through global assay harmonization and a major company wide research reorganization.
  • Pfizer Global Research & Development
    Principal Scientist
    Pfizer Global Research & Development 2004 - 2011
    Greater San Diego Area
    Solve cytochrome P450 mediated drug metabolism and DDI issues on drug discovery projects using cytochrome P450 crystallization and in silico approaches to understand ligand binding. Provide drug metabolism enzymology expertise to drug projects.
  • The Scripps Research Institute
    Postdoctoral Research Associate
    The Scripps Research Institute 1998 - 2004
    Greater San Diego Area
    Mentor Dr. Eric JohnsonWorked to heterologously express, purify, crystallize and solve the structure of mammalian cytochrome P450 enzymes; rabbit CYP2C5, and human CYP2C9 and CYP3A4 in the presence and absence of ligands and inhibitors.Performed studies to understand the specificity of rabbit nuclear hormone receptor PXR using transiently transfected cells.
  • The Agouron Institute
    Research Associate
    The Agouron Institute 1995 - Jun 1998
    Greater San Diego Area
    Mentor Dr. Judy Raucy Graduate Research Associate as part of PhD work. Purified CYP2C19 from human liver and characterized metabolism of exogenous substrates. Characterized recombinantly expressed CYP2C8, CYP2C9 and CYP2C19.
  • University Of New Mexico
    Research Assistant, Department Of Toxicology, College Of Pharmacy
    University Of New Mexico 1993 - 1995
    Albuquerque, New Mexico Area
    Mentor Dr. Judy Raucy. Graduate Research Associate as part of PhD work. Purified CYP2C19 from human liver and characterized metabolism of exogenous substrates. Characterized recombinantly expressed CYP2C8, CYP2C9 and CYP2C19.
  • International Research And Development Company (Irdc)
    Chemist, Inhalation Toxicology Department
    International Research And Development Company (Irdc) 1990 - 1993
    Mattawan, Mi
    Responsible for the generation and characterization (concentration and particle size) of inhalation toxicology test atmospheres.

Michael Wester Skills

Enzyme Kinetics Drug Metabolism Adme Drug Discovery Dmpk Pharmacokinetics Bioanalysis In Vitro Lc Ms Drug Design Drug Interactions Pharmacodynamics Hplc Pharmacology Elisa Purification Protein Expression Uv/vis Cell Culture Molecular Biology Gas Chromatography Metabolism High Throughput Screening Toxicology

Michael Wester Education Details

Frequently Asked Questions about Michael Wester

What company does Michael Wester work for?

Michael Wester works for Vertex Pharmaceuticals

What is Michael Wester's role at the current company?

Michael Wester's current role is Research Fellow I at Vertex Pharmaceuticals.

What is Michael Wester's email address?

Michael Wester's email address is mr****@****ail.com

What is Michael Wester's direct phone number?

Michael Wester's direct phone number is +185840*****

What schools did Michael Wester attend?

Michael Wester attended The University Of New Mexico, Western Michigan University.

What skills is Michael Wester known for?

Michael Wester has skills like Enzyme Kinetics, Drug Metabolism, Adme, Drug Discovery, Dmpk, Pharmacokinetics, Bioanalysis, In Vitro, Lc Ms, Drug Design, Drug Interactions, Pharmacodynamics.

Who are Michael Wester's colleagues?

Michael Wester's colleagues are Marcelo Torezan, Kristina Simacek, Phd, Joel Smith, Hayley Adamuska, Darryl Darryl_patrick, Julia Shard, Alam Lakhani.

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