Michael Yi

Michael Yi Email and Phone Number

Associate Director at CARGO Therapeutics @ CARGO Therapeutics
Michael Yi's Location
San Francisco Bay Area, United States, United States
Michael Yi's Contact Details

Michael Yi personal email

n/a
About Michael Yi

Self-motivated protein biochemist with a strong foundation in molecular biology, cell culture, protein purification and protein analytics. I also have extensive experience with assay development, microscopy and enzymology. Able to take a project from start to finish with little managing or oversight. Driven, diligent and able to solve and troubleshoot complex issues. Looking for fast-paced, collaborative and challenging work environments.

Michael Yi's Current Company Details
CARGO Therapeutics

Cargo Therapeutics

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Associate Director at CARGO Therapeutics
Michael Yi Work Experience Details
  • Cargo Therapeutics
    Associate Director
    Cargo Therapeutics Mar 2024 - Present
    San Carlos, California, Us
    Project lead in Research and Discovery for next-generation CAR T cells overcoming mechanisms of resistance in heme malignancies. Focus is on design and delivery of complex, multicistronic viral vectors that enhance persistence of CAR T cells in hostile immune environments.
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  • Cargo Therapeutics
    Senior Scientist Ii
    Cargo Therapeutics Aug 2021 - Mar 2024
    San Carlos, California, Us
    Early member of company and research group. Involved in preclinical development of CRG-023 (trispecific CAR T targeting CD19/CD20/CD22) and project lead for other discovery efforts.
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  • Allogene Therapeutics
    Senior Scientist
    Allogene Therapeutics Jan 2020 - Aug 2021
    South San Francisco, California, Us
    Worked in research and development for identification of next gen strategies to avoid allogeneic rejection of our CAR T cells. Focus was on developing strategies for enhanced immune cloaking. Established in vitro models to assess allogeneic rejection by T, NK and PBMCs.
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  • Pact Pharma
    Scientist Ii
    Pact Pharma Feb 2019 - Oct 2019
    South San Francisco, California, Us
    View
  • Pact Pharma
    Scientist
    Pact Pharma Apr 2018 - Feb 2019
    South San Francisco, California, Us
    Early member of protein sciences group. Established high-throughput platform for generating libraries of soluble peptide-MHC proteins harboring neoepitopes that would ultimately be used to isolate neoantigen-specific CD8+ T cells from peripheral blood.
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  • Stanford University
    Ph.D Candidate
    Stanford University Sep 2012 - Mar 2018
    Stanford, Ca, Us
    Doctoral Research: Spearheaded several projects investigating the chemical biology of two redox-regulated proteins, transglutaminase 2 (TG2) and thioredoxin-1 (TRX), and their role in the pathogenesis of celiac disease. • Produced protocols for expression and purification of various recombinant proteins in E. coli using IMAC, SEC, and IEX.• Identified regulatory mechanisms for allosteric control of TG2 enzymatic activity using in vitro enzymatic assays• Performed several cell-based assays to assess potency of TG2 inhibitors, including in situ enzymatic assays and immunofluorescence• Developed model to study extracellular TG2 biology with primary mouse cells using lentivirus• Established and maintained a BSL-2+ work environment including upkeep of protocols • Mentored undergraduate researchers and several rotation students
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  • Tufts University
    Undergraduate Research
    Tufts University Oct 2009 - May 2012
    Medford, Massachusetts, Us
    Worked with graduate student on his metabolic network modeling project. Also, I ran my own independent project where I studied the redox balance of hepatocytes undergoing non-alcoholic fatty liver disease-like conditions.
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Michael Yi Skills

Matlab Mathematical Modeling Chemistry Fluorescence Microscopy Pcr Spectroscopy C++ Nanotechnology Flow Cytometry Protein Engineering Protein Purification Elisa Characterization Afm Simulations Lc Ms Gc Ms Western Blotting Lentivirus Transfection Tissue Culture Cell Based Assays Enzyme Assays Protein Conjugation Immunoprecipitation Sirna In Vitro Image Analysis Site Directed Mutagenesis Enzyme Kinetics Cloning Iex Immunofluorescence Mutagenesis Celiac Disease Conjugation High Performance Liquid Chromatography Molecular Biology Protein Chemistry Protein Expression Protein Assays Protein Production Protein Labeling Endotoxin Fast Protein Liquid Chromatography Sds Page Chemical Biology

Michael Yi Education Details

  • Stanford University
    Stanford University
    Chemical Engineering
  • Tufts University
    Tufts University
    Chemical And Biological Engineering
  • Shelton High School
    Shelton High School
    High School Diploma

Frequently Asked Questions about Michael Yi

What company does Michael Yi work for?

Michael Yi works for Cargo Therapeutics

What is Michael Yi's role at the current company?

Michael Yi's current role is Associate Director at CARGO Therapeutics.

What is Michael Yi's email address?

Michael Yi's email address is my****@****bal.net

What is Michael Yi's direct phone number?

Michael Yi's direct phone number is +120327*****

What schools did Michael Yi attend?

Michael Yi attended Stanford University, Tufts University, Shelton High School.

What skills is Michael Yi known for?

Michael Yi has skills like Matlab, Mathematical Modeling, Chemistry, Fluorescence Microscopy, Pcr, Spectroscopy, C++, Nanotechnology, Flow Cytometry, Protein Engineering, Protein Purification, Elisa.

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