Michael Marella Email & Phone Number

Perform organic synthesis on milligram to multigram scale including purification of intermediates and final compounds.Traveled internationally in support of technology transfer.

Rheumatoid Arthritis Research: Kinase Antagonist ProgramRational design and synthesis of novel small molecules evaluated in primary and secondary assays.CNS Indications: Estrogen Receptor Beta Agonist Program Design and synthesis of novel phenol heterocyclic compounds as a potential second series.Women's Health (Hot Flush Program): Norepinephrine Reuptake Inhibitor:Designed and synthesized novel phenylpropylamines as backups to post-Discovery toxicology candidates.

Progesterone Receptor Agonist/Antagonist Program Contributor to the design and synthesis of novel Pyrrole-Oxindole progesterone modulators. Prepared small molecule libraries for ligand based evaluation on biological targets.

Peripheral Kappa Agonist ProgramDesign and synthesis of novel arylacetamides for the biological evaluation of effects in pain models.