Phenomics provides tools and animal and cell-based models to support the large-scale systematic study of gene function. Phenomics enables the collaboration of Australia’s leading researchers in the fields of health genomics, basic biology, and clinical studies. By partnering we accelerate the better understanding of normal gene function and the discovery of links between faulty genes and disease that will lead to new therapies.Phenomics Australia is an alliance between 17 of Australia’s… Show more Phenomics provides tools and animal and cell-based models to support the large-scale systematic study of gene function. Phenomics enables the collaboration of Australia’s leading researchers in the fields of health genomics, basic biology, and clinical studies. By partnering we accelerate the better understanding of normal gene function and the discovery of links between faulty genes and disease that will lead to new therapies.Phenomics Australia is an alliance between 17 of Australia’s leading universities and medical research institutes. The partnership has built and continues to develop research infrastructure capability on a national scale to efficiently deliver a range of services and expertise to all Australian biomedical researchers. Producing and describing new models of human disease, Phenomics Australia safeguards and distributes those models to national and international researchers, and enhances Australian participation and leadership in international biomedical research.Our mission is to build and maintain a national system of capabilities and expert knowledge where all information and research is focused on addressing national research priorities and solving health challenges. Phenomics Australia is the leading focal point for international cooperation and collaboration. Australia’s involvement in the significant medical research investments in the Northern Hemisphere depends on the Phenomics Australia connection. The technologies encompassed by the Phenomics Australia will continue to provide critical infrastructure for the biomedical research community as the era of precision medicine dawns and promises to transform society. Show less

The mission of the National Centre for Indigenous Genomics (NCIG) is to establish a managed collection of Indigenous biospecimens and associated data that can be used by bona fide researchers, under Indigenous governance, for projects that aim to provide broad benefit to: the people and communities providing the biospecimens or their descendants; the broader Indigenous community; and the general Australian community.NCIG aims to establish a national resource, under Indigenous… Show more The mission of the National Centre for Indigenous Genomics (NCIG) is to establish a managed collection of Indigenous biospecimens and associated data that can be used by bona fide researchers, under Indigenous governance, for projects that aim to provide broad benefit to: the people and communities providing the biospecimens or their descendants; the broader Indigenous community; and the general Australian community.NCIG aims to establish a national resource, under Indigenous governance, for appropriate and respectful genetic and genomic research that will benefit Indigenous Australians. The Australian National University (ANU) holds a substantial collection of biological samples obtained from Indigenous Australians for the purposes of scientific research. NCIG was established in 2013 following the recommendations of an external Consultative Committee of eminent Indigenous Australians. NCIG is governed by an Indigenous-majority Governance Board and receives advice from a Research Advisory Committee. Since 2014 NCIG has begun consultation with Indigenous communities and families who donated samples held at the ANU.NCIG is the first facility of its kind in Australia and the second in the world. Policies and procedures developed by NCIG will provide a model for the conduct of genetic research with Indigenous people globally, and inform national and international policies for storage and use of biological samples collected from Indigenous communities. Show less

The Australian Phenomics Facility works with medical researchers to help discover new gene functions and genetic causes of human disease. I work directly with researchers to develop new projects that capitalize on the powerful phenomics and genomics tools we offer.

The Australian Phenomics Network (APN) provides Australian and international researchers with tools to better understand gene function and to study human disease. The network is Australian government funded and consists of leading Australian universities and medical research institutes, offering expertise and equipment to create, characterise and curate mouse strains for medical research.

The Australian Phenomics Network (APN) provides Australian and international researchers with tools to better understand gene function and to study human disease. The network is Australian government funded and consists of leading Australian universities and medical research institutes, offering expertise and equipment to create, characterise and curate mouse strains for medical research.

Investigated the role of Eph receptors and ephrin ligands in tumour growth and angiogenesis, particularly in lung and bladder cancer.

Academic and industrial collaborative projects investigating factors that determine the blood-brain barrier function and the permeability of the barrier to natural and synthetic pharmaceuticals with potential therapeutic neuroprotective activity.

Investigated the role of the antioxidant glutathione in cells of the blood-brain barrier: its role in protection against barrier and neuronal injury induced by oxidative stress.

Investigated the pathogenesis of cerebral malaria in African children, principally measuring metabolites in cerebral spinal fluid using gas chromatography-mass spectrometry.

Department of Clinical Immunology: Conducted ELISA, enzyme immunoassays and radioimmunoassays.