Michael Houghton

Michael Houghton Email and Phone Number

Lecturer & Research Fellow in Molecular Nutrition @ Monash University
Michael Houghton's Location
Melbourne, Victoria, Australia, Australia
Michael Houghton's Contact Details

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About Michael Houghton

An emerging early career researcher with a background in cell metabolism, biochemistry and molecular nutrition. My research is focused on the association between biologically active dietary components, metabolism and chronic disease risk factors. I am an expert in cell culture, ion chromatography, droplet digital PCR, automated Westerns, advanced plate reader assays and cell respirometry.I have advanced our understanding of how dietary (poly)phenols protect hepatic, muscle and adipose cells from metabolic stress and regulate metabolic pathways at the molecular level in relation to translatable effects in vivo. I characterised a human skeletal muscle cell model for use in metabolism research, and exploited this model to investigate the influence of gut microbiome catabolites on insulin signalling and glucose metabolism, demonstrating a novel link between diet, the microbiome and energy source utilisation. I have developed novel chromatographic methods for the highly specific, sensitive and accurate quantification of carbohydrates in cells and culture media, in vitro enzyme assays, foods and beverages, blood and urine. These methods have been used to measure sugars and oligosaccharides in amylase and glucosidase inhibition assays, revising and advancing our knowledge on the inhibitory potential and complexation mechanisms of other nutrients with carbohydrates in the gut.When the COVID-19 global pandemic hit, I led urgent in vitro mechanistic work investigating potential prophylactic compounds against the SARS-CoV-2 infection. I characterised a suitable lung epithelial cell model in a physiologically-relevant air-liquid interface, and others including nasal and gut cells, in order to screen the effects of treatments on the expression of the key coronavirus entry proteins, and am in collaboration with The Peter Doherty Institute to test promising candidates on SARS-CoV-2 infectivity.In addition to research, I have have guest-lectured for several BSc and MSc units, co-supervised an Honours student to completion and am currently co-supervising two PhD students. I chair the ECR Committee at the multi-institutional, interdisciplinary Monash Health Translation Precinct and sit on the Faculty ECR Steering Committee. My work has been presented at five international conferences, I was invited to speak at an international respirometry workshop, and I conceived and organised three student conferences.

Michael Houghton's Current Company Details
Monash University

Monash University

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Lecturer & Research Fellow in Molecular Nutrition
Michael Houghton Work Experience Details
  • Monash University
    Lecturer
    Monash University Jan 2024 - Present
    Melbourne, Australia
    Lecturer and Unit Coordinator on the Bachelor of Nutrition Science and Master of Food Science and Agribusiness courses at Monash University. Inspiring the next generation of scientists and healthcare professionals to improve human health and performance through nutrition.
  • Monash University
    Research Fellow
    Monash University Jun 2019 - Present
    Melbourne, Victoria, Australia
    Overseeing the Williamson Molecular Nutrition Lab in the Department of Nutrition, Dietetics and Food at the Monash Victorian Heart Institute. Investigating how diet affects the risk of chronic diseases, especially type 2 diabetes and cardiovascular disease, using cellular mechanistic studies and human interventions. Supervising wonderfully talented PhD students.
  • Ski Beat
    Chalet Host
    Ski Beat Dec 2017 - Apr 2018
    Plan Peisey, Les Arcs, France
    Took some time out of academia after my PhD to work a ski season in the French Alps!
  • University Of Leeds
    Research Assistant
    University Of Leeds Jun 2017 - Nov 2017
    Leeds, United Kingdom
    While writing my PhD thesis, I continued working in the same lab as an RA.
  • Anglian Water Services
    Laboratory Technician
    Anglian Water Services Dec 2011 - Sep 2013
    Huntingdon
    Worked in the Metals lab analysing samples from throughout the water system by use of inductively coupled plasma mass spectrometry and optical emission spectroscopy for regulatory and investigative purposes, following Good Laboratory Practice guidelines and working in accordance to UKAS-accredited quality procedures.
  • The Open University
    Research Laboratory Technician
    The Open University Nov 2010 - Jul 2013
    Milton Keynes, United Kingdom
    Worked in the Department of Life, Health and Chemical Sciences on a research project investigating the effects of ageing on the enteric nervous system in mice. Responsible for the immunohistochemical preparation of gut tissues including sampling, fixing, cryo-sectioning and whole mount preparation, immuno-labelling, confocal microscopy, and the analysis of acquired images.After completing my contract in August 2011, I remained a visiting researcher to the department to assist in the handover and completion of the project, and the writing up of our manuscript and funding applications.
  • Cultural Community Partnerships
    Leisure Assistant
    Cultural Community Partnerships Mar 2005 - Aug 2012
    Thrapston, Northamptonshire
  • Lancaster University
    Leisure Assistant
    Lancaster University Oct 2007 - Jun 2010

Michael Houghton Skills

Microscopy Mass Spectrometry Research Biochemistry Molecular Biology Cell Biology Microbiology Chemistry Immunohistochemistry Icp Ms Icp Oes Optical Emission Spectroscopy Immunology Data Analysis Life Sciences Microsoft Office Lifesciences Laboratory Biotechnology Spectroscopy Chromatography Glp Genetics Purification Analytical Chemistry Gel Electrophoresis Protein Assays Enzyme Assays Cellular Assays Cell Culture Assay Development Science Cell Laboratory Skills

Michael Houghton Education Details

Frequently Asked Questions about Michael Houghton

What company does Michael Houghton work for?

Michael Houghton works for Monash University

What is Michael Houghton's role at the current company?

Michael Houghton's current role is Lecturer & Research Fellow in Molecular Nutrition.

What is Michael Houghton's email address?

Michael Houghton's email address is mi****@****aol.com

What schools did Michael Houghton attend?

Michael Houghton attended University Of Leeds, Lancaster University.

What are some of Michael Houghton's interests?

Michael Houghton has interest in Molecular Biology, Rugby Union, Water Polo, Biochemistry, Nutrition, Metabolism, Endurance Events, Cycling, Cell Culture, Cell Biology.

What skills is Michael Houghton known for?

Michael Houghton has skills like Microscopy, Mass Spectrometry, Research, Biochemistry, Molecular Biology, Cell Biology, Microbiology, Chemistry, Immunohistochemistry, Icp Ms, Icp Oes, Optical Emission Spectroscopy.

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