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Michael B Plewe Email & Phone Number

Senior Vice President - Medicinal Chemistry at Cullgen Inc. at Cullgen Inc.
Location: San Diego, California, United States 9 work roles 5 schools
3 work emails found @cullgen.com 3 phones found area 919 and 212 LinkedIn matched
✓ Verified Jun 2026 4 data sources Profile completeness 100%

Contact Signals · 3 work emails · 3 phones

Work email m****@cullgen.com
Direct phone (919) ***-****
LinkedIn Profile matched
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Current company
Role
Senior Vice President - Medicinal Chemistry at Cullgen Inc.
Location
San Diego, California, United States

Who is Michael B Plewe? Overview

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Quick answer

Michael B Plewe is listed as Senior Vice President - Medicinal Chemistry at Cullgen Inc. at Cullgen Inc., based in San Diego, California, United States. AeroLeads shows a work email signal at cullgen.com, phone signal with area code 919, 212, and a matched LinkedIn profile for Michael B Plewe.

Michael B Plewe previously worked as Senior Vice President - Medicinal Chemistry at Cullgen Inc. and Head of Chemistry at Arisan Therapeutics, Inc. Michael B Plewe holds Biotech Project Management Certificate from Uc San Diego.

Company email context

Email format at Cullgen Inc.

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{first_initial}{last}@cullgen.com
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AeroLeads found 3 current-domain work email signals for Michael B Plewe. Compare company email patterns before reaching out.

Profile bio

About Michael B Plewe

Accomplished medicinal chemist and project leader with proven ability to drive projects efficiently from hit identification to clinical development candidates.● Expert knowledge of targeted protein degradation (TPD) technologies● Broad understanding of drug discovery process and pre-clinical development● Demonstrated project management, leadership, communication and negotiation skills.● Expertise in multiple therapeutic areas: Oncology, Ophthalmology, Antiviral, Diabetes● Extensive knowledge in optimization of physicochemical properties, pharmacokinetics, metabolism, and toxicity (ADMET) of drug candidates.●Broad experience managing outsourcing efforts to foreign (Asian, European) CROs.●Certified Project Management Professional (PMP)Recent publications:Le P.T, Cheng, H.; Ninkovic,S.; Plewe, M., et. al. Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Ka and mTOR. Biorg. Med. Chem. Lett. 2012, 22, 5098–5103.Plewe, M. B., Johnson, T. W, Azaindole Hydroxamic Acids are HIV Integrase Inhibitors. In: HIV-1 Integrase, Mechanism and Inhibitor Design, N. Neamati, Ed.; Wiley: Hoboken, 2011, 265 – 274.Johnson, T. W. ; Tanis, S. P.; Plewe, M. B et al. Design and Synthesis of N-Hydroxy-Dihydronaphthyridinones as Potent and Orally Bioavailable HIV-1 Integrase Inhibitors. J. Med. Chem. 2011, 54, 3393 – 3417.Tanis, S. P.; Plewe, M. B.; Johnson, T. W. et al., Azaindole N-Methyl Hydroxamic Acids as HIV Integrase Inhibitors - II. The Impact of Physicochemical Properties on ADME and PK. Biorg. Med. Chem. Lett. 2010, 20, 7429 - 7434.Specialties: targeted protein degradation, E3-ligases, PROTAC, drug discovery, medicinal chemistry, project management, oncology, antivirals, ophthalmology, virtual screening, structure-based-drug-design (SBDD), hit-to-lead, lead development, ADMET, databases (Scifinder, Reaxys), Spotfire, patents, outsourcing.

Listed skills include Drug Discovery, Medicinal Chemistry, Chemistry, Biotechnology, and 20 others.

Current workplace

Michael B Plewe's current company

Company context helps verify the profile and gives searchers a useful next step.

Cullgen Inc.
Cullgen Inc.
Senior Vice President - Medicinal Chemistry at Cullgen Inc.
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9 roles · 33 years

Michael B Plewe work experience

A career timeline built from the work history available for this profile.

Senior Vice President - Medicinal Chemistry

Current

San Diego, California, US

Responsible for operations of US headquarter in San Diego and world-wide medicinal chemistry; oversee research and development of novel molecules for targeted protein degradation using uSMITE (TM) technology

Apr 2018 - Present

Head Of Chemistry

Set up new chemistry laboratory; devised medicinal chemistry strategies for hit-to-lead campaigns; designed and synthesized templates and small focused libraries for hit expansion and IP generation; prepared several NIH SBIR grant applications; Principal Investigator on NIH grants "Optimization of Arenavirus Antivirals" Phase I and "Arenavirus antiviral.

2011 - 2018 ~7 yrs

President/Vp Education/Vp Public Relations

Englewood, Colorado, US

Scheduled club meetings, prepared agendas, recruited and oriented new club members to Toastmasters program, webmaster.Publicized club activities both internally to members and externally to various audiences through media outlets. Created and updated the club's websites and social media pages.

2010 - 2015 ~5 yrs

Volunteer

US

Responsible for identifying and coordinating speakers and host sites for monthly Southern California breakfast meeting.

2010 - 2013 ~3 yrs

Associate Research Fellow

New York, New York, US

  • Took leading role in devising and implementing a unified medicinal chemistry strategy; coordinated chemistry efforts; advised on strategies for novel exploratory projects; parallel medicinal chemistry (PMC) expert.
  • Initiated hit-to-lead campaign for an oncology kinase program using combinatorial libraries and SBDD and discovered novel scaffolds for selective inhibitors
2007 - 2010 ~3 yrs

Senior Principal Scientist

New York, New York, US

  • Project leader for a multidisciplinary project team; devised and implemented unified medicinal chemistry strategies addressing goals and issues for multiple projects
  • Led a multidisciplinary team that successfully nominated two development candidates for antiviral (HIV) program; developed project charter, defined project strategies, chaired project meetings, ensured follow-through.
  • Explored SAR and optimized physicochemical properties of novel series of HIV-Integrase inhibitors balancing potency, metabolic stability and permeability of initial lead
2004 - 2007 ~3 yrs

Senior Scientist Ii

New York, New York, US

  • Independently designed synthetic targets based on project objectives and SAR data; coordinated chemistry efforts; supervised associates; project leader for multidisciplinary project team
  • Discovered novel class of HIV Integrase inhibitors; explored SAR through combinatorial libraries; modified physicochemical properties leading to improve ADME
  • Took on project leadership, organized project meetings, planned multi-parameter analysis of existing lead matter leading to prioritization of chemistry efforts
  • Delivered first clinical development candidate for HIV Integrase project
  • Compiled experimental sections for filing of patent applications in timely manner
2000 - 2004 ~4 yrs

Senior Scientist

Alanex / Agouron / Pfizer
  • Designed and synthesized glucagon antagonists for treatment of type II diabetes
  • Developed novel templates and protocols for combinatorial libraries allowing rapid exploration of lead matter
1997 - 2000 ~3 yrs

Research Scientist

San Diego, CA, US

  • designed and synthesized novel cationic lipid based transfecting agents for DNA delivery and gene therapy.
1993 - 1997 ~4 yrs
5 education records

Michael B Plewe education

Biotech Project Management Certificate

Uc San Diego

Biotech Project Management Certificate

University Of Washington

Post Doc, Organic Chemistry

Uc Irvine

Dr. Rer. Nat., Organic Chemistry

University Of Konstanz

Diploma, Chemistry

University Of Konstanz
FAQ

Frequently asked questions about Michael B Plewe

Quick answers generated from the profile data available on this page.

What company does Michael B Plewe work for?

Michael B Plewe works for Cullgen Inc..

What is Michael B Plewe's role at Cullgen Inc.?

Michael B Plewe is listed as Senior Vice President - Medicinal Chemistry at Cullgen Inc. at Cullgen Inc..

What is Michael B Plewe's email address?

AeroLeads has found 3 work email signals at @cullgen.com for Michael B Plewe at Cullgen Inc..

What is Michael B Plewe's phone number?

AeroLeads has found 3 phone signal(s) with area code 919, 212 for Michael B Plewe at Cullgen Inc..

Where is Michael B Plewe based?

Michael B Plewe is based in San Diego, California, United States while working with Cullgen Inc..

What companies has Michael B Plewe worked for?

Michael B Plewe has worked for Cullgen Inc., Arisan Therapeutics, Inc, Toastmasters International, Biopharmapm, and Pfizer.

How can I contact Michael B Plewe?

You can use AeroLeads to view verified contact signals for Michael B Plewe at Cullgen Inc., including work email, phone, and LinkedIn data when available.

What schools did Michael B Plewe attend?

Michael B Plewe holds Biotech Project Management Certificate from Uc San Diego.

What skills is Michael B Plewe known for?

Michael B Plewe is listed with skills including Drug Discovery, Medicinal Chemistry, Chemistry, Biotechnology, Oncology, Organic Chemistry, Pharmaceutical Industry, and Cro.

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