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I've supervised technicians and students, obtained grants, directed self-designed projects, and worked as a consultant, with more than 40 articles in the peer-reviewed literature.Challenging positions in cancer immunology, generating basic, translational, and pre-clinical data for diverse projects are my passion.I'm proficient in 43-metal CyTOF, acquisition of data using a Hyperion imaging mass cytometer (IMC), 21-color flow cytometry panel design, human and cynomolgus macaque immunology, Luminex cytokine assays, BrdU, CFSE, TUNEL, DiCO6(3), JC-1, annexin-V, M30, fluorescence-activated cell sorting (FACS), magnetic cell sorting (MACS), transwell, chemotaxis, immunoblotting, ELISA, cell based assays, in vitro cytotoxicity, colony forming assays, and colorimetric assays, with software proficiency in Cytobank, FCS Express, FlowJo, MultiCycle, DIVA, xPonent, Excel, and PowerPoint.
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Principal ScientistXencor Sep 2021 - PresentPasadena, California, Us -
Research Scientist In The Single Cell, Sequencing, And Cytof (Sc2) CoreChildren'S Hospital Los Angeles (Chla) Jun 2020 - Sep 2021Los Angeles, Ca, Us -
Scientific Director, Flow Cytometry Core FacilityChildren'S Hospital Los Angeles 2007 - Jun 2020Oversight of a flow cytometry core facility operating a FACS-Aria cell sorter, an LSR-II analyzer, and a Luminex-200 for a large group of users, whom I assisted with data analyses and with design of experimental protocols. Concomitantly, I was involved in clinical trials examining the effects of therapeutic drugs on a wide range of immunological parameters using 12-color flow cytometric immunophenotyping and Luminex, and was involved in research evaluating immune modulation strategies for cancer therapy.
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Sr. Post-Doctoral FellowChildren'S Hospital Los Angeles 2003 - 2007Two first-authored, peer-reviewed articles resulted from this fellowship.
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Head Of The Laboratory For Apoptosis ResearchMasaryk Memorial Cancer Institute 1999 - 2003Directing a PhD student and two technicians, my lab published projects related to therapeutic elimination of tumor cells.
Michael Sheard Skills
Michael Sheard Education Details
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Charles UniversityOncology
Frequently Asked Questions about Michael Sheard
What company does Michael Sheard work for?
Michael Sheard works for Xencor
What is Michael Sheard's role at the current company?
Michael Sheard's current role is Principal Scientist - Flow Cytometry Group.
What is Michael Sheard's email address?
Michael Sheard's email address is sh****@****ail.com
What is Michael Sheard's direct phone number?
Michael Sheard's direct phone number is +131079*****
What schools did Michael Sheard attend?
Michael Sheard attended Charles University.
What are some of Michael Sheard's interests?
Michael Sheard has interest in Polychromatic Flow Cytometry, Clinical Trials, Oncology, Immunology, Biomedical Research, Cancer Biology.
What skills is Michael Sheard known for?
Michael Sheard has skills like Flow Cytometry, Cell Culture, Cell, Immunology, Western Blotting, Elisa, Protein Chemistry, Cancer, Facs, Cell Biology, Laboratory, In Vitro.
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